Reverse Genetic Analysis of the Transcription Regulatory Sequence of the Coronavirus Transmissible Gastroenteritis Virus
2004 ◽
Vol 78
(11)
◽
pp. 6061-6066
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Keyword(s):
ABSTRACT Coronavirus discontinuous transcription uses a highly conserved sequence (CS) in the joining of leader and body RNAs. Using a full-length infectious construct of transmissable gastroenteritis virus, the present study demonstrates that subgenomic transcription is heavily influenced by upstream flanking sequences and supports a mechanism of transcription attenuation that is regulated in part by a larger domain composed of primarily upstream flanking sequences which select appropriately positioned CS elements for synthesis of subgenomic RNAs.
1991 ◽
Vol 65
(6)
◽
pp. 3369-3373
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2000 ◽
Vol 74
(22)
◽
pp. 10600-10611
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1981 ◽
1994 ◽
Vol 68
(12)
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pp. 8008-8016
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1986 ◽
Vol 67
(7)
◽
pp. 1419-1425
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1993 ◽
Vol 5
(1)
◽
pp. 16-20
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1994 ◽
pp. 305-310
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Keyword(s):