scholarly journals Characterization of Apicomplexan Amino Acid Transporters (ApiATs) in the Malaria Parasite Plasmodium falciparum

mSphere ◽  
2021 ◽  
Author(s):  
Jan Stephan Wichers ◽  
Carolina van Gelder ◽  
Gwendolin Fuchs ◽  
Julia Mareike Ruge ◽  
Emma Pietsch ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Amino Acid ◽  
Malaria Parasite ◽  
Host Cells ◽  
Amino Acid Transporters ◽  
Malaria Parasites ◽  
Parasite Plasmodium ◽  
Parasite Plasmodium Falciparum ◽  
Intracellular Proliferation

Malaria parasites live and multiply inside cells. To facilitate their extremely fast intracellular proliferation, they hijack and transform their host cells.

scholarly journals Characterization of the accessible genome in the human malaria parasite Plasmodium falciparum

2018 ◽  
Vol 46 (18) ◽  
pp. 9414-9431 ◽  
Author(s):  
José Luis Ruiz ◽  
Juan J Tena ◽  
Cristina Bancells ◽  
Alfred Cortés ◽  
José Luis Gómez-Skarmeta ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Malaria Parasite ◽  
Human Malaria Parasite ◽  
Human Malaria ◽  
Parasite Plasmodium ◽  
Parasite Plasmodium Falciparum

scholarly journals Structure-Based Identification and Functional Characterization of a Lipocalin in the Malaria Parasite Plasmodium falciparum

Cell Reports ◽  
2020 ◽  
Vol 31 (12) ◽  
pp. 107817
Author(s):  
Paul-Christian Burda ◽  
Thomas Crosskey ◽  
Katharina Lauk ◽  
Aimo Zurborg ◽  
Christoph Söhnchen ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Malaria Parasite ◽  
Functional Characterization ◽  
Parasite Plasmodium ◽  
Parasite Plasmodium Falciparum

scholarly journals Characterization of class II apurinic/apyrimidinic endonuclease activities in the human malaria parasite, Plasmodium falciparum

1999 ◽  
Vol 345 (1) ◽  
pp. 85-89 ◽  
Author(s):  
Brett M. HALTIWANGER ◽  
Natalie O. KARPINICH ◽  
Theodore F. TARASCHI
Keyword(s):  
Plasmodium Falciparum ◽  
Malaria Parasite ◽  
Class Ii ◽  
Human Malaria Parasite ◽  
Human Malaria ◽  
Starting Point ◽  
Parasite Plasmodium ◽  
Parasite Plasmodium Falciparum ◽  
Ap Sites

We have reported that the human malaria parasite, Plasmodium falciparum, repairs apurinic/apyrimidinic (AP) sites on DNA by a long-patch base excision repair (BER) pathway. This biology is different from that in mammalian cells, which predominantly repair AP sites by a DNA-polymerase-β-dependent, one-nucleotide patch BER pathway. As a starting point for the identification and biochemical characterization of the enzymes involved in the parasite DNA BER pathway, we chose characterization of the AP endonuclease activity in a P. falciparum cell-free lysate. Evidence is provided for the presence of class II, Mg2+-dependent and independent AP endonucleases in the parasite lysate. The investigation of the processing of AP sites in Plasmodium will provide new information about long-patch BER pathways; if they are different from those in the human host they might provide a new target for anti-malarial chemotherapy.

Characterization of human malaria parasite Plasmodium falciparum eIF4E homologue and mRNA 5′ cap status

2007 ◽  
Vol 155 (2) ◽  
pp. 146-155 ◽  
Author(s):  
Philip J. Shaw ◽  
Napawan Ponmee ◽  
Nitsara Karoonuthaisiri ◽  
Sumalee Kamchonwongpaisan ◽  
Yongyuth Yuthavong
Keyword(s):  
Plasmodium Falciparum ◽  
Malaria Parasite ◽  
Human Malaria Parasite ◽  
Human Malaria ◽  
Parasite Plasmodium ◽  
Parasite Plasmodium Falciparum

Molecular cloning and characterization of a peroxiredoxin from the human malaria parasite Plasmodium falciparum

2000 ◽  
Vol 109 (2) ◽  
pp. 165-169 ◽  
Author(s):  
Shin-ichiro Kawazu ◽  
Naotoshi Tsuji ◽  
Toshimitsu Hatabu ◽  
Satoru Kawai ◽  
Yoshitsugu Matsumoto ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Molecular Cloning ◽  
Malaria Parasite ◽  
Human Malaria Parasite ◽  
Human Malaria ◽  
Parasite Plasmodium ◽  
Parasite Plasmodium Falciparum
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