Influence of extraction properties of PVC plasticizer membrane on the response of coated wire type ion selective electrode

The authors studied the influence of the extraction properties of a PVC membrane plasticizer of a coated-wire type ion-selective electrode on its response in titrations of brucine and atropine with sodium tetraphenyl borate, as well as in potentiometric determinations of these compounds. The highest attainable value of the ion pair concentration in the plasticizer, which is limited by the distribution coefficient of the ion pair, determines the interval in which the electrode potential can be changed; and a linear dependence of the potential range of the titration curves on the logarithm of the ion-pair distribution coefficient was found. The slope of the dependence of the electrode potential on the logarithm of the ion concentration to be determined, found in potentiometric measurements, is proportional to the distribution coefficient of the ion which forms a pair with the ion to be determined and in whose solution the electrode membrane is activated between the measurements. The dependence of the slope of the electrode function on the logarithm of the product of the mentioned distribution coefficients is linear.

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The Coated-Wire Ion Selective Electrode (CWISE) of Chromate Using PVC-Membrane Based on Chitosan as A Carrier

The Journal of Pure and Applied Chemistry Research ◽

10.21776/ub.jpacr.2012.001.01.104 ◽

2012 ◽

Vol 1 (1) ◽

pp. 33-40 ◽

Cited By ~ 5

Author(s):

Dedeh Kurniasih ◽

◽

Atikah Atikah ◽

Hermin Sulistyarti ◽

◽

...

Keyword(s):

Ion Selective Electrode ◽

Pvc Membrane ◽

Selective Electrode ◽

Coated Wire

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COATED WIRE LEAD ION SELECTIVE ELECTRODE BASED ON DITHIZONE

Al-Azhar Bulletin of Science ◽

10.21608/absb.2011.7016 ◽

2011 ◽

Vol 22 (Issue 2-A) ◽

pp. 45-51

Keyword(s):

Ion Selective Electrode ◽

Lead Ion ◽

Selective Electrode ◽

Coated Wire

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A Novel Potentiometric PVC-membrane Cysteamine-Selective Electrode Based on Cysteamine-Phosphomolybdate Ion-Pair

Current Pharmaceutical Analysis ◽

10.2174/1573412914666181017150529 ◽

2020 ◽

Vol 16 (2) ◽

pp. 168-175 ◽

Cited By ~ 3

Author(s):

Merve Tumur ◽

Gulsah Saydan Kanberoglu ◽

Fatih Coldur

Keyword(s):

Analytical Methods ◽

Pharmaceutical Preparations ◽

Life Time ◽

Ion Pair ◽

Pharmaceutical Formulation ◽

Pvc Membrane ◽

Selective Electrode ◽

Potentiometric Response ◽

Drug Quality Control

Background: Cysteamine is used as an orphan drug in the treatment of cystinosis to prevent long-term cystine accumulation in lysosomes. Dosing in cysteamine treatment is extremely important and overdose may cause some side effects. Up to now, various analytical methods have been used for cysteamine determination. Many of these methods require sophisticated instruments, expert operators, time-consuming measurement procedures and manipulation steps, expensive supplies and long analysis time. Aims and Objective: The present study deals with the development of a potentiometric PVC-membrane cysteamine-selective electrode based on an ion-pair of cysteamine and its application in a pharmaceutical formulation. Methods: Cysteamine (Cys)-Phosphomolybdate (PM) ion-pair was synthesized by mixing the equal volumes of 10-2 M Cysteamine HCl and sodium phosphomolybdate aqueous solutions. The obtained precipitate was used as ionophore in the structure of PVC-membrane. Results and Discussion: The electrode exhibited a linear response in the concentration range of 1.0×10- 1-1.0×10-5 M cysteamine with a slope of 51,7 mV per decade and detection limit of 1.0×10-5 M. The potentiometric response of the electrode was very rapid (5 s), adequately repeatable, stable and selective. pH working range and life-time of the electrode were also determined as 3.0-7.0 and 25 days, respectively. Conclusion: A PVC-membrane cysteamine selective electrode was easily prepared. Cysteamine determination in a pharmaceutical formulation was performed. Analysis results indicated that it can be successfully used in drug quality control laboratories for routine analysis of cysteamine in pharmaceutical preparations alternative to more sophisticated, expensive and time-consuming analytical methods.

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Coated-Wire Silver Ion-Selective Electrode Based on Silver Complex of Cyclam.

Analytical Sciences ◽

10.2116/analsci.17.477 ◽

2001 ◽

Vol 17 (4) ◽

pp. 477-479 ◽

Cited By ~ 22

Author(s):

Aparna SIL ◽

Vijaykumar S. IJERI ◽

Ashwini K. SRIVASTAVA

Keyword(s):

Silver Ion ◽

Silver Complex ◽

Ion Selective Electrode ◽

Selective Electrode ◽

Coated Wire

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A New method for ISE construction for methyl orange dyes and using for indirect determination of Amitriptyline Hydrochloried drug

Baghdad Science Journal ◽

10.21123/bsj.12.1.188-196 ◽

2015 ◽

Vol 12 (1) ◽

pp. 188-196

Author(s):

Baghdad Science Journal

Keyword(s):

Methyl Orange ◽

Response Time ◽

Electrode Surface ◽

Ion Pair ◽

New Method ◽

Ion Selective Electrode ◽

Selective Electrode ◽

Internal Solution ◽

Indirect Determination

A new method for construction ion-selective electrode (ISE) by heating reaction of methyl orange with ammonium reineckate using PVC as plasticizer for determination methyl orange and determination Amitriptyline Hydrochloried drug by formation ion-pair on electrode surface . The characteristics of the electrode and it response as following : internal solution 10-4M , pH (2.5-5) ,temperature (20-30) and response time 2 sec. Calibration response for methyl orange over the concentrationrange 10-3 -10-9 M with R=0.9989 , RSD%=0.1052, D.O.L=0.315X10-9 MEre%=(-0.877- -2.76) , Rec%.=(97.230 -101.711) .

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Analysis of Bromide Ion in Wine by Ion Selective Electrode

Journal of AOAC INTERNATIONAL ◽

10.1093/jaoac/59.1.53 ◽

1976 ◽

Vol 59 (1) ◽

pp. 53-55

Author(s):

James E Graf ◽

Troy E Vaughn ◽

William H Kipp

Keyword(s):

Country Of Origin ◽

Ion Selective Electrode ◽

Ion Concentration ◽

Selective Electrode ◽

Bromide Ion

Abstract The use of the bromide ion selective electrode for the determination of bromide ion in wine has been found to be rapid and reliable. The method has been used for still wines and carbonated wines and is applicable to all wines regardless of their country of origin. The method consists of treating a 50 ml aliquot of wine with 2 ml each of 3.75M H3PO4, saturated KNO3, and 1M CuSO4. After 10 min the electrodes are immersed in the samples and a millivolt reading is obtained. One hundred μl 500 ppm bromide ion standard is added and the millivolt reading is taken. Bromide ion concentration in the wine = (CΔ × 1)/((antilog ΔE/S) − 1) where CΔ = 1, ΔE = the change in potential expressed in millivolts, and S = the electrode slope.

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Ion-Selective Electrodes Sensitive to Organic Ions. I. The Saccharin Electrode

Journal of AOAC INTERNATIONAL ◽

10.1093/jaoac/57.5.1205 ◽

1974 ◽

Vol 57 (5) ◽

pp. 1205-1208

Author(s):

Norio Hazemoto ◽

Naoki Kamo ◽

Yonosuke Kobatake

Keyword(s):

Ion Association ◽

Ion Selective Electrode ◽

Ion Concentration ◽

Ion Selective Electrodes ◽

Selective Electrode ◽

Organic Ions ◽

Sodium Cyclamate

Abstract An ion-selective electrode responsive to saccharin was made by dissolving an ion association which exists between iron(II)-bathophenanthroline chelate and saccharin in nitrobenzene. The electrode developed was capable of measuring saccharin ion concentration in the presence of other sweetening substances, e.g., saccharose, glucose, sodium cyclamate, and sorbitol, over the concentration range of 10-1 to 10-5M.

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Preparation, Characterization, and Analytical Application of Ramipril Membrane-Based Ion-Selective Electrode

International Journal of Analytical Chemistry ◽

10.1155/2009/954083 ◽

2009 ◽

Vol 2009 ◽

pp. 1-7 ◽

Cited By ~ 3

Author(s):

Hassan Arida ◽

Mona Ahmed ◽

Abdallah Ali

Keyword(s):

Pharmaceutical Formulations ◽

Ion Pair ◽

Pvc Membrane ◽

Ion Selective Electrodes ◽

Selective Electrode ◽

Response Sensitivity ◽

Direct Potentiometry ◽

Plasticized Pvc ◽

Electrochemical Evaluation

The fabrication and electrochemical evaluation of two PVC membrane-based Ion-Selective electrodes responsive for ramipril drug have been proposed. The sensitive membranes were prepared using ramipril-phosphomolibdate and ramipril-tetraphenylborate ion-pair complexes as electroactive sensing materials in plasticized PVC support. The electrodes based on these materials provide near-Nernestian response (sensitivity of53±0.5–54±0.5 mV/concentration decade) covering the concentration range of1.0×10-2–1.0×10-5 molL−1with a detection limit of3.0×10-6–4.0×10-6 molL−1. The suggested electrodes have been successfully used in the determination of ramipril drug in some pharmaceutical formulations using direct potentiometry with average recovery of >96% and mean standard deviation of <3% (n=5).

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