A6.19 Non-canonical NF-κB signalling in endothelial cells promotes angiogenesis in a novel 3D model of rheumatoid arthritis synovial angiogenesis

2015 ◽  
Vol 74 (Suppl 1) ◽  
pp. A63.1-A63
Author(s):  
CX Maracle ◽  
B Helder ◽  
AR Noort ◽  
C van der Horst ◽  
SW Tas
Keyword(s):  
Rheumatoid Arthritis ◽  
Endothelial Cells ◽  
3D Model

scholarly journals Enhanced generation of endothelial cells from CD34+ cells of the bone marrow in rheumatoid arthritis: Possible role in synovial neovascularization

2004 ◽  
Vol 50 (12) ◽  
pp. 3888-3896 ◽  
Author(s):  
Shunsei Hirohata ◽  
Tamiko Yanagida ◽  
Akihide Nampei ◽  
Yasuo Kunugiza ◽  
Hideo Hashimoto ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Marrow ◽  
Endothelial Cells ◽  
Cd34 Cells

OP0272 Identification of New Inhibitors of Angiogenesis in A Novel 3d Model of Rheumatoid Arthritis Synovial Angiogenesis

2016 ◽  
Vol 75 (Suppl 2) ◽  
pp. 161.2-161
Author(s):  
C.X. Maracle ◽  
P. Kucharzewska ◽  
B. Helder ◽  
H. Olsson ◽  
S.W. Tas
Keyword(s):  
Rheumatoid Arthritis ◽  
3D Model

Rheumatoid Arthritis: Pathophysiology

1999 ◽  
Vol 12 (4) ◽  
pp. 282-292 ◽  
Author(s):  
Walter F. Stanaszek ◽  
Bruce C. Carlstedt
Keyword(s):  
Rheumatoid Arthritis ◽  
Endothelial Cells ◽  
Environmental Factors ◽  
Immune Complexes ◽  
Disease Process ◽  
Signs And Symptoms ◽  
Diagnostic Parameters

This article reviews the incidence, etiology, and pathophysiology of rheumatoid arthritis (RA), along with signs and symptoms, laboratory, and other diagnostic parameters of the disease. Criteria utilized for defining RA are discussed. While the primary cause is unknown, theories implicate genetic, hormonal, viral, bacterial, autoimmune, atmospheric, and environmental factors. Recent studies focus on the role of immune complexes, endothelial cells, and antibodies in the disease process.

scholarly journals Cross-linking of IgGs bound on circulating neutrophils leads to an activation of endothelial cells: possible role of rheumatoid factors in rheumatoid arthritis-associated vascular dysfunction

2013 ◽  
Vol 10 (1) ◽  
pp. 27 ◽  
Author(s):  
Emmanuelle Rollet-Labelle ◽  
Myriam Vaillancourt ◽  
Louis Marois ◽  
Marianna M Newkirk ◽  
Patrice E Poubelle ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Endothelial Cells ◽  
Vascular Dysfunction ◽  
Cross Linking ◽  
Rheumatoid Factors
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