Isolated duodenal varices as the initial presentation of hepatocellular carcinoma

Hepatoblastoma (HB) is a rare malignant tumour of the liver and usually occurs in the first three years of life. Hepatoblastoma in adolescents and young adults is extremely rare; nevertheless the prognosis is much worse than in childhood, because these kinds of tumours are usually diagnosed late. Characteristic imaging and histopathological and AFP levels help in the diagnosis of hepatoblastoma. Paraneoplastic features of hepatoblastoma are not uncommon at presentation and include erythrocytosis, thrombocytosis, hypocalcaemia, isosexual precocious puberty, and rarely hypoglycaemia. Even though hypoglycaemia is commonly seen in hepatocellular carcinoma, its association with hepatoblastoma is very rare. We present a case of 15-year-old male patient presenting with complaints of recurrent hypoglycaemic seizures ultimately leading to diagnosis of hepatoblastoma. Managed successfully with neoadjuvant chemotherapy, surgery and adjuvant chemotherapy with adriamycin and cisplatin based regimens. An extensive review of literature in the PubMed and MEDLINE did not reveal much data on paraneoplastic recurrent hypoglycaemic seizures as an initial presentation of hepatoblastomas in adolescents and young adults.

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A Rapidly Enlarging Thyroid Mass as the Initial Presentation of Metastatic Hepatocellular Carcinoma

Thyroid ◽

10.1089/thy.2005.15.1399 ◽

2005 ◽

Vol 15 (12) ◽

pp. 1399-1400 ◽

Cited By ~ 3

Author(s):

Fatih Tunca ◽

Yasemin Giles ◽

Mine Güllüoǧlu ◽

Yasemin Özlük ◽

Tarık Terzioǧlu ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Initial Presentation ◽

Thyroid Mass ◽

Metastatic Hepatocellular Carcinoma

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Bilateral Endogenous Endophthalmitis as an Initial Presentation of Klebsiella pneumoniae Bacteremia in Advanced Hepatocellular Carcinoma

Ophthalmology Research An International Journal ◽

10.9734/or/2015/17730 ◽

2015 ◽

Vol 4 (1) ◽

pp. 34-40

Author(s):

Rhuen Chow ◽

Tengku Kamalden

Keyword(s):

Hepatocellular Carcinoma ◽

Klebsiella Pneumoniae ◽

Initial Presentation ◽

Endogenous Endophthalmitis ◽

Advanced Hepatocellular Carcinoma

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S2720 Hemorrhagic Shock as Initial Presentation of Hepatocellular Carcinoma: A Case Series

The American Journal of Gastroenterology ◽

10.14309/01.ajg.0000712928.51765.7e ◽

2020 ◽

Vol 115 (1) ◽

pp. S1421-S1421

Author(s):

Cynthia Rivas ◽

Arturo Suplee Rivera ◽

Asif Zamir

Keyword(s):

Hepatocellular Carcinoma ◽

Hemorrhagic Shock ◽

Case Series ◽

Initial Presentation

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Shoulder Mass as the Initial Presentation of Metastatic Hepatocellular Carcinoma

ACG Case Reports Journal ◽

10.14309/crj.2017.72 ◽

2017 ◽

Vol 4 (1) ◽

pp. e72

Author(s):

Derek B. Laskar ◽

Ghulam Ilyas ◽

Daniel Diaz ◽

Charles Shao

Keyword(s):

Hepatocellular Carcinoma ◽

Initial Presentation ◽

Metastatic Hepatocellular Carcinoma

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A rare case of cranial metastasis from an initial presentation of hepatocellular carcinoma

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20203469 ◽

2020 ◽

Vol 8 (8) ◽

pp. 3088

Author(s):

Chetan Kalal ◽

Adinath Wagh ◽

Atif Patel ◽

Harshad Joshi ◽

Ravindra Surude ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Rare Case ◽

Parietal Bone ◽

Initial Presentation ◽

Cross Sectional ◽

Detailed History ◽

Cross Sectional Imaging ◽

History Of ◽

Sectional Imaging ◽

Cranial Metastasis

Cranial metastases from hepatocellular carcinoma (HCC) has been seldom reported. Reported herein is the case of a painless parietal bone mass as an initial presentation of HCC in a 63-year-old female patient who was subsequently diagnosed to have HCV related cirrhosis. The biopsy from cranial lesion was confirmatory of HCC on immunohistochemistry. The patient had no known history of chronic liver disease. The presented diagnosis was made through detailed history, laboratory parameters and cross sectional imaging.

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