scholarly journals Acute parvovirus B19 infection in identical twins unmasking previously unidentified hereditary spherocytosis

2014 ◽  
Vol 2014 (jul29 1) ◽  
pp. bcr2013202957-bcr2013202957 ◽  
Author(s):  
D. G. Forde ◽  
A. Cope ◽  
B. Stone
Keyword(s):  
Hereditary Spherocytosis ◽  
Parvovirus B19 ◽  
Identical Twins ◽  
Parvovirus B19 Infection

scholarly journals Clinical Case of Aplastic Crisis Associated with Extramedullary Hematopoiesis in an Adult With Hereditary Spherocytosis and Parvovirus B19 Infection

2015 ◽  
Vol 34 (1-2) ◽  
pp. 39-44
Author(s):  
Andreea Jercan ◽  
Rusu Munteanu Gina ◽  
Camelia Dobrea ◽  
Daniel Coriu ◽  
Aurelia Tatic
Keyword(s):  
Hereditary Spherocytosis ◽  
Parvovirus B19 ◽  
Extramedullary Hematopoiesis ◽  
Blood Film ◽  
Red Cell Membrane ◽  
Infectious Episode ◽  
Indirect Bilirubin ◽  
Aplastic Crisis ◽  
Chronic Hemolysis ◽  
Parvovirus B19 Infection

Abstract Hereditary spherocytosis is an inherited hemolytic anemia due to red cell membrane defects, characterised by chronic hemolysis with different severity degrees, splenomegaly and microspherocytosis on the peripheral blood film. Among the possible complications in these patients are aplastic crisis and extramedullary hematopoiesis. In this article we present the case of a 42 years old man with hereditary spherocytosis diagnosed during childhood (average haemoglobin (Hb) value of 11-12 g/dl), which presented with worsening anemia, fever, chills, bone and muscle pain. The evolution was with accentuation of anemia (Hb 4.2 g/dl), decease of reticulocyte number (Ret 0,8%) and bilirubin (indirect bilirubin 2.7 g/dl). ParvovirusB19 DNA was 100.000.000 copies/ml. A computer tomography (CT)scan was performed and showed extramedullary hematopoiesis areas situated paravertebraly in the inferior thorax and hepatosplenomegaly. The infectious episode was self-limited and improved with substitution treatment.

scholarly journals Role of Surgical Intervention in Hereditary Spherocytosis with Haemolytic Anaemia, Splenomegaly and Jaundice

2021 ◽  
pp. 222-226
Author(s):  
K. Senthil Kumar ◽  
K. Abinaya ◽  
R. Anantharamakrishnan ◽  
K. Pranay
Keyword(s):  
Haemolytic Anaemia ◽  
Surgical Intervention ◽  
Hereditary Spherocytosis ◽  
Parvovirus B19 ◽  
Folic Acid Deficiency ◽  
Acid Deficiency ◽  
Parvovirus B19 Infection ◽  
Current Infection ◽  
One Year

haemolytic anaemia, splenomegaly and jaundice, admitted in Chettinad hospital and research institute during one year period from  January 2019 to January 2020. Surgical intervention is indicated for selected patients with hereditary spherocytosis with haemolytic anaemia and jaundice to abate the hemolytic process after correction of anaemia with blood transfusion. Pigmented gallstones are seen in more than 50% cases for which incidence increases with severity of hemolysis and with age. Complications include aplastic anemia (most common after parvovirus B19 infection), haemolytic crisis during inter-current infection, megaloblastic crisis – during folic acid deficiency, cardiomyopathy, hematological malignancies.

Acute Encephalopathy With Human Parvovirus B19 Infection in Hereditary Spherocytosis

2008 ◽  
Vol 27 (7) ◽  
pp. 651-652 ◽  
Author(s):  
Koichi Oshima ◽  
Akira Kikuchi ◽  
Shinji Mochizuki ◽  
Takashi Arai ◽  
Tsutomu Oishi ◽  
...  
Keyword(s):  
Hereditary Spherocytosis ◽  
Parvovirus B19 ◽  
Human Parvovirus B19 ◽  
Acute Encephalopathy ◽  
Parvovirus B19 Infection

Pancytopenia with hemophagocytosis secondary to parvovirus B19 infection in a family with hereditary spherocytosis

1999 ◽  
Vol 41 (5) ◽  
pp. 561-564 ◽  
Author(s):  
TOSHIYA Sato ◽  
DAISUKE Ueda ◽  
SHIN-ICHIRO Sakota ◽  
KEIJI Haseyama ◽  
SHUNZO Chiba ◽  
...  
Keyword(s):  
Hereditary Spherocytosis ◽  
Parvovirus B19 ◽  
Parvovirus B19 Infection

scholarly journals Aplastic crisis due to human parvovirus B19 infection in hereditary hemolytic anaemia

1992 ◽  
Vol 34 (5) ◽  
pp. 479-482 ◽  
Author(s):  
R. C. N. Cubel ◽  
M. C. Valadão ◽  
W. V. Pereira ◽  
M. C. Magalhães ◽  
J. P. Nascimento
Keyword(s):  
Sickle Cell ◽  
Rio De Janeiro ◽  
Sickle Cell Anaemia ◽  
Hereditary Spherocytosis ◽  
Parvovirus B19 ◽  
Human Parvovirus B19 ◽  
Aplastic Crisis ◽  
Parvovirus B19 Infection ◽  
Transient Aplastic Crisis ◽  
Santa Maria

Specific anti-B19 IgM was demonstrated in sera from three children showing transient aplastic crisis. A two years-old boy living in Rio de Janeiro suffering from sickle-cell anaemia showed the crisis during August, 1990. Two siblings living in Santa Maria, RS, developed aplastic crisis during May, 1991, when they were also diagnosed for hereditary spherocytosis. For a third child from this same family, who first developed aplastic crisis no IgM anti-B19 was detected in her sera.

Aplastic Crisis Secondary to Parvovirus B19 Infection as the First Manifestation of an Undiagnosed Hereditary Spherocytosis

2016 ◽  
Vol 38 (1) ◽  
pp. 81-82 ◽  
Author(s):  
Anna Alonso-Saladrigues ◽  
Albert Català ◽  
Rubén Berrueco ◽  
Mireia Camós ◽  
Montserrat Torrebadell ◽  
...  
Keyword(s):  
Hereditary Spherocytosis ◽  
Parvovirus B19 ◽  
Aplastic Crisis ◽  
Parvovirus B19 Infection
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