scholarly journals Sentinel bruising as a presentation of metastatic melanoma

2019 ◽  
Vol 12 (2) ◽  
pp. e228114 ◽  
Author(s):  
Lloyd Steele ◽  
Chit Cheng Yeoh
Keyword(s):  
Weight Loss ◽  
Skin Lesions ◽  
Lymph Node Biopsy ◽  
Cutaneous Malignant Melanoma ◽  
Subcutaneous Nodule ◽  
Rare Presentation ◽  
Subcutaneous Nodules ◽  
Node Biopsy ◽  
Melanoma Metastases ◽  
History Of

A 46-year-old man presented with a 4-week history of bruising with subcutaneous nodules and weight loss. He also had a 2-week history of progressive back and hip pain. He had been diagnosed with stage Ib cutaneous melanoma 30 months previously, which had been fully excised. A sentinel lymph node biopsy was negative. On examination, there were five skin lesions at different stages. Each had spontaneously appeared as a bruise with a central subcutaneous nodule, and the bruising then faded to leave a persistent subcutaneous nodule. Excision of one of the nodules demonstrated a 4.5 mm diameter partly necrotic melanoma deposit in the dermis. CT scan of the head, chest, abdomen and pelvis showed widespread metastases. This rare presentation of cutaneous malignant melanoma metastases has been termed ‘sentinel bruising’. There are fewer than 10 cases reported in the literature.

scholarly journals Coexistence of Ankylosing Spondylitis and Löfgren’s Syndrome

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Senol Kobak ◽  
Fidan Sever ◽  
Oya Sivrikoz ◽  
Ahmet Karaarslan
Keyword(s):  
Ankylosing Spondylitis ◽  
Low Dose ◽  
Histopathological Examination ◽  
Skin Lesions ◽  
Lymph Node Biopsy ◽  
Node Biopsy ◽  
Löfgren’S Syndrome ◽  
Significant Regression ◽  
Dose Corticosteroid ◽  
Thorax Ct

A 46-year-old male patient diagnosed with ankylosing spondylitis presented to our polyclinic with complaints of pain, swelling, and limitation in joint mobility in both ankles and erythema nodosum skin lesions in both pretibial sites. The sacroiliac joint graphy and the MRI taken revealed active and chronic sacroiliitis. On the thorax CT, multiple mediastinal and hilar lymphadenopathies were reported. Mediastinoscopic excisional lymph node biopsy was taken and noncalcified granulomatous structures, lymphocytes, and histiocytes were determined on histopathological examination. The patients were diagnosed with ankylosing spondylitis, sarcoidosis, and Löfgren’s syndrome. NSAIDs, sulfasalazine, and low dose corticosteroid were started. Significant regression was seen in the patient’s subjective and laboratory assessments.

Sentinel lymph node biopsy for cutaneous malignant melanoma ; clinical significance

Skin Cancer ◽  
2021 ◽  
Vol 36 (2) ◽  
pp. 173-179
Author(s):  
Tatsuya TSUDA ◽  
Yoshiro ABE ◽  
Soushi ISHIDA ◽  
Kazuhide MINEDA ◽  
Yutaro YAMASHITA ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Malignant Melanoma ◽  
Clinical Significance ◽  
Lymph Node Biopsy ◽  
Cutaneous Malignant Melanoma ◽  
Node Biopsy

scholarly journals Kikuchi-Fujimoto Disease: A Report of 3 Cases

2007 ◽  
Vol 86 (7) ◽  
pp. 412-413 ◽  
Author(s):  
Eimear Phelan ◽  
Emer Lang ◽  
Peter Gormley ◽  
John Lang
Keyword(s):  
Weight Loss ◽  
Cervical Lymphadenopathy ◽  
Lymph Node Biopsy ◽  
Accurate Diagnosis ◽  
Histiocytic Necrotizing Lymphadenitis ◽  
Kikuchi’S Disease ◽  
Node Biopsy ◽  
Night Sweats ◽  
Necrotizing Lymphadenitis ◽  
Kikuchi's Disease

Cervical lymphadenopathy has many underlying etiologies. One of its rare causes is Kikuchi-Fujimoto disease (Kikuchi's disease, histiocytic necrotizing lymphadenitis). We discovered such a cause in a 37-year-old woman who had presented with malaise, night sweats, and weight loss in addition to cervical lymphadenopathy. We based our diagnosis on excisional lymph node biopsy. We also review 2 other cases of Kikuchi's disease that were diagnosed by others at our institution. Clinically and histologically, Kikuchi's disease is very similar to lymphoma, and distinguishing the two is difficult. However, despite the fact that Kikuchi's disease is benign, an accurate diagnosis is important because misdiagnosis might lead to unnecessary surgery and/or chemotherapy.

The History of Sentinel Lymph Node Biopsy

2015 ◽  
Vol 21 (1) ◽  
pp. 3-6 ◽  
Author(s):  
Omgo E. Nieweg ◽  
Roger F. Uren ◽  
John F. Thompson
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Lymph Node Biopsy ◽  
Node Biopsy ◽  
History Of

scholarly journals The Dangers of Immediately Performing a Sensitive and Specific Investigation versus the Dangers of Delaying It: A Cautionary Case of Hodgkin’s Lymphoma

2020 ◽  
Author(s):  
Takahiro Ito ◽  
Hiroshi Sawachika ◽  
Yukinori Harada ◽  
Taro Shimizu
Keyword(s):  
Lymph Node ◽  
Hodgkin’S Lymphoma ◽  
Gastrointestinal Endoscopy ◽  
Lymph Node Biopsy ◽  
Hodgkin's Lymphoma ◽  
Haemophagocytic Lymphohistiocytosis ◽  
Gastrointestinal Malignancies ◽  
Node Biopsy ◽  
History Of ◽  
Diagnostic Outcome

A 60-year-old man was admitted with a 1-month history of fever and weight loss. Multiple lymphadenopathies and haemophagocytic lymphohistiocytosis were noted from the beginning, suggesting lymphoma. However, lymph node biopsy was deferred because lymph node biopsy was regarded as being invasive and requires general anaesthesia, and because other possible differential diagnoses including gastrointestinal malignancies and TAFRO syndrome were being considered. Instead, investigations including gastrointestinal endoscopy and bone marrow biopsy were prioritized. The patient was eventually diagnosed with Hodgkin’s lymphoma based on lymph node biopsy but died during chemotherapy. Physicians should prioritize the tests that are most directly related to the diagnostic outcome, even if they are invasive.

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