P-ANCA vasculitis with diffuse alveolar haemorrhage preceded by a spider bite

2020 ◽  
Vol 13 (6) ◽  
pp. e233710
Author(s):  
Ali Hameed Ali ◽  
Mandip Singh Kang ◽  
Jaafar Aldahwi ◽  
Candice Reyes
Keyword(s):  
Supplemental Oxygen ◽  
Alveolar Haemorrhage ◽  
Diffuse Alveolar Haemorrhage ◽  
Black Widow ◽  
Anca Vasculitis ◽  
Hypoxic Respiratory Failure ◽  
Spider Bites ◽  
Spider Bite ◽  
Work Up ◽  
Widow Spider

We report a patient with antineutrophilic cytoplasmic antibody (ANCA) vasculitis that was preceded by witnessed black widow spider bites. The patient initially presented with a diffuse painful skin rash that developed after a few hours post bite. He was treated initially with topical ointment for the suspected bite. However, subsequently a few days later the patient returned to the hospital with similar, but more progressive rash with haemoptysis and acute hypoxic respiratory failure requiring supplemental oxygen. Immunology work up showed elevated titre of peri-nuclear ANCA. Bronchoscopy revealed diffuse alveolar haemorrhage. The patient was treated successfully with methylprednisolone and rituximab.

Diffuse alveolar haemorrhage: a rare complication of clopidogrel use

2021 ◽  
Vol 14 (8) ◽  
pp. e244314
Author(s):  
Rachelle Soriano ◽  
Saud Al-Rawaf ◽  
Khalil Diab
Keyword(s):  
Differential Diagnosis ◽  
Native American ◽  
Rare Complication ◽  
American Woman ◽  
Alveolar Haemorrhage ◽  
High Dose ◽  
Diffuse Alveolar Haemorrhage ◽  
Carotid Artery Stent ◽  
Hypoxic Respiratory Failure ◽  
Work Up

Diffuse alveolar haemorrhage (DAH) has been reported as a rare complication of clopidogrel use and is usually a diagnosis of exclusion. We describe the case of an 88-year-old Native American woman who presented with acute hypoxic respiratory failure with CT scan of the chest showing diffuse bilateral ground-glass opacities. She had been on clopidogrel for 6 months for a carotid artery stent. Bronchoscopy with bronchoalveolar lavage and transbronchial biopsies revealed DAH. Infectious and autoimmune work-up were all negative. Clopidogrel was stopped and high-dose steroids were started. Her symptoms gradually improved until she was discharged from the hospital. The differential DAH is broad. Anticoagulant-induced DAH should be part of the differential diagnosis, and is usually a diagnosis of exclusion.

scholarly journals Acute urinary retention after Black Widow envenomation: a case report

CJEM ◽  
2017 ◽  
Vol 20 (4) ◽  
pp. 640-642 ◽  
Author(s):  
Matthew Carere ◽  
Russel Sterret ◽  
Nicholas Timmerman ◽  
Ian Taylor
Keyword(s):  
Climate Change ◽  
Differential Diagnosis ◽  
Case Report ◽  
Acute Abdomen ◽  
Urinary Retention ◽  
Acute Urinary Retention ◽  
Black Widow ◽  
Spider Bite ◽  
Work Up ◽  
Widow Spider

AbstractLatrodectism following Black Widow envenomation is rare in Canada. We present the case of a previously healthy 50 year old male who presented with an acute abdomen, hypertension, and urinary retention. After a thorough work up it was determined to be as a result of a Black Widow spider bite. Due to climate change we may see more cases of Latrodectism in the future and it should be considered as a differential diagnosis in anyone presenting with an acute abdomen after an insect bite.

scholarly journals Black widow spider bite in Johannesburg

2018 ◽  
Vol 33 (3) ◽  
pp. 86-88 ◽  
Author(s):  
Teressa S. Thomas ◽  
Alan Kemp ◽  
Kim P. Roberg
Keyword(s):  
South Africa ◽  
Clinical Presentation ◽  
Favourable Outcome ◽  
Muscle Rigidity ◽  
Black Widow ◽  
Black Widow Spider ◽  
Appropriate Treatment ◽  
Spider Bites ◽  
Spider Bite ◽  
Widow Spider

Black widow spider bites are uncommon in South Africa, but it is important for clinicians to be aware of the clinical presentation in order to initiate appropriate treatment. This case highlights the presentation and management of a middle-aged gentleman who presented to the Chris Hani Baragwanath hospital following a spider bite. The bite was later confirmed to be that of a black widow spider. The patient presented with the typical symptoms of latrodectism – autonomic dysfunction, muscle rigidity and cramps – and was managed symptomatically with a favourable outcome.

28362 Black widow spider bite: A common creature in an uncommon geographic location

2021 ◽  
Vol 85 (3) ◽  
pp. AB185
Author(s):  
Marely Santiago Vazquez ◽  
Osward Y. Carrasquillo ◽  
Natalia M. Pelet del Toro ◽  
Francisco Colón Fontanez
Keyword(s):  
Geographic Location ◽  
Black Widow ◽  
Black Widow Spider ◽  
Spider Bite ◽  
Widow Spider

Letter: Attempted suicide by black widow spider bite

JAMA ◽  
1976 ◽  
Vol 235 (25) ◽  
pp. 2718a-2719 ◽  
Author(s):  
D. P. Fisher
Keyword(s):  
Attempted Suicide ◽  
Black Widow ◽  
Black Widow Spider ◽  
Spider Bite ◽  
Widow Spider

scholarly journals BLACK WIDOW SPIDER BITE

1942 ◽  
Vol 115 (2) ◽  
pp. 249-257 ◽  
Author(s):  
H.T. KIRBY-SMITH ◽  
SEWANEE TENN
Keyword(s):  
Black Widow ◽  
Black Widow Spider ◽  
Spider Bite ◽  
Widow Spider

Pathologically confirmed diffuse alveolar haemorrhage in lymphangioleiomyomatosis

2021 ◽  
Vol 14 (11) ◽  
pp. e238713
Author(s):  
Jane Kobylianskii ◽  
Adam Hutchinson-Jaffe ◽  
Michael Cabanero ◽  
John Thenganatt
Keyword(s):  
Lung Biopsy ◽  
Histopathological Examination ◽  
Chest Ct ◽  
Ground Glass ◽  
Alveolar Haemorrhage ◽  
Vascular Endothelial ◽  
Diffuse Alveolar Haemorrhage ◽  
Endothelial Growth Factor ◽  
Work Up

A 40-year-old woman was referred to pulmonology after presenting with dyspnoea and self-limiting haemoptysis. Chest CT revealed diffuse ground glass opacities and small thin-walled cysts. Bronchoalveolar lavage cultures were negative and cytology revealed haemosiderin-laden macrophages. Transthoracic echocardiogram was normal. Connective tissue disease and vasculitis work-up were negative. Vascular endothelial growth factor-D level was indeterminate. Lung function was normal. She underwent video-assisted thoracoscopic lung biopsy. In addition to findings consistent with lymphangioleiomyomatosis, histopathological examination identified haemosiderosis without capillaritis, confirming a diagnosis of diffuse alveolar haemorrhage in the context of the associated clinical and radiographic features. Follow-up imaging after 5 months showed resolution of the diffuse ground glass opacities. Pharmacotherapy with sirolimus was not initiated due to absence of deterioration in pulmonary function. Diffuse alveolar haemorrhage in patients with lymphangioleiomyomatosis is a rare but important presentation. The few previously reported cases progressed to respiratory failure requiring mechanical ventilation.

Black Widow Spider Bites in the Adult Male

1943 ◽  
Vol 92 (4) ◽  
pp. 427-432
Author(s):  
Bert L. Halter ◽  
William C. Kuzell
Keyword(s):  
Adult Male ◽  
Black Widow ◽  
Black Widow Spider ◽  
Spider Bites ◽  
Widow Spider
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