Complicated and persistent severe COVID-19 pneumonia in a recipient of allogeneic haematopoietic stem cell transplant
Keyword(s):
We describe the case of a 45-year-old man affected by T-cell acute lymphoblastic leukaemia and diagnosed with COVID-19 early after an allogeneic haematopoietic stem cell transplant. The infectious disease was characterised by a severe and prolonged course, further complicated by a spontaneous pneumomediastinum and pneumopericardium. We successfully treated this patient with the antiviral drug remdesivir associated with two courses of COVID-19 convalescent plasma. This case report represents a good example of the typical clinical course of COVID-19 in severely immunosuppressed patients and gives evidence that in this population only a prompt treatment directed towards viral clearance can face the absence of a valid immune reactivity.
2019 ◽
2009 ◽
Vol 15
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pp. 865-868
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2015 ◽
Vol 25
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pp. 402-418
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2013 ◽
Vol 108
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pp. 119-122
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2013 ◽
Vol 58
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pp. 733-736
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2016 ◽
Vol 22
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pp. 946.e1-946.e8
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2017 ◽
2014 ◽
Vol 78
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pp. 836-846
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