Characteristics of early filtering blebs that predict successful trabeculectomy identified via three-dimensional anterior segment optical coherence tomography

2017 ◽  
Vol 102 (6) ◽  
pp. 796-801 ◽  
Author(s):  
Akiko Narita ◽  
Yuki Morizane ◽  
Tomoe Miyake ◽  
Jiro Seguchi ◽  
Tetsuya Baba ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Wall Thickness ◽  
Univariate Analysis ◽  
Anterior Segment ◽  
Three Dimensional ◽  
Multivariate Logistic Regression Analysis ◽  
Case Series ◽  
Maximum Height ◽  
Optical Coherence ◽  
Case Series Study

Background/aimsTo identify the cross-sectional characteristics of filtering blebs at 2 weeks post-trabeculectomy associated with intraocular pressure (IOP) control at 1 year post-trabeculectomy.MethodsNinety-nine eyes of 94 patients who had undergone primary trabeculectomy were included in this retrospective consecutive case series study. Surgical success was defined as an IOP ≤15 mm Hg and a >20% reduction in IOP without glaucoma medication or additional glaucoma surgeries at 1 year post-trabeculectomy. Subjects were classified into two groups according to whether surgery was successful or unsuccessful. Blebs were examined using swept-source three-dimensional anterior segment optical coherence tomography and evaluated for quantitative parameters, including maximum height, maximum wall thickness and ratio of hyporeflective space of the wall, as well as qualitative parameters, including multiple parallel hyporeflective layers within the wall (striping phenomenon), decreased visibility of the sclera underlying the bleb (shading phenomenon) and cyst-like structures of the wall.ResultsSeventy-seven eyes (77.8%) were assigned to the successful group and 22 (22.2%) to the unsuccessful group. Univariate analysis showed significant differences between the groups regarding maximum bleb height (p=0.044), maximum bleb wall thickness (p=0.017) and the striping phenomenon of the bleb wall (p=0.007). Multivariate logistic regression analysis confirmed that the striping phenomenon at 2 weeks post-trabeculectomy was significantly associated with success at 1 year post-trabeculectomy (OR 3.405; 95% CI 1.059 to 10.947; p=0.040).ConclusionTaller blebs with thicker walls that showed the striping phenomenon at 2 weeks post-trabeculectomy appeared to predict good IOP control at 1 year post-trabeculectomy.

scholarly journals Optical Coherence Tomography Reveals New Insights into the Accommodation Mechanism

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Mahmoud Mohamed Farouk ◽  
Takeshi Naito ◽  
Kayo Shinomiya ◽  
Hiroshi Eguchi ◽  
Khulood Mohammed Sayed ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Outcome Measures ◽  
Anterior Segment ◽  
Case Series ◽  
Optical Coherence ◽  
Anterior Pole ◽  
Forward Movement ◽  
Anterior Segment Oct ◽  
Lens Thickness ◽  
Significant Difference

Purpose. To evaluate the movement of the anterior and posterior lens poles during naturally stimulated accommodation in children using anterior segment optical coherence tomography (OCT).Methods. This is a prospective, observational, noncomparative case series including 18 eyes of nine children. Analysis of the anterior segment in the accommodated and unaccommodated state (with cycloplegia) was done using anterior segment OCT. The main outcome measures were the position of the anterior and posterior lens poles (in relation to the cornea) and lens thickness (LT).Results. A Statistically significant forward movement of the anterior lens pole and backward movement of the posterior lens pole with an increase in LT were found during accommodation (P<0.001). There was no significant difference between the degree of movement of the anterior lens pole and the posterior lens pole during accommodation (P=0.944).Conclusions. Anterior segment OCT provides a rapid noncontact method for studying accommodation in children. The backward movement of the posterior lens pole during accommodation nearly equals the forward movement of its anterior pole. These data minimize the theoretical hydraulic effect of the vitreous during accommodation, adding more support to the capsular theory of Helmholtz.

scholarly journals Optical distortion correction in Optical Coherence Tomography for quantitative ocular anterior segment by three-dimensional imaging

2010 ◽  
Vol 18 (3) ◽  
pp. 2782 ◽  
Author(s):  
Sergio Ortiz ◽  
Damian Siedlecki ◽  
Ireneusz Grulkowski ◽  
Laura Remon ◽  
Daniel Pascual ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Three Dimensional ◽  
Distortion Correction ◽  
Optical Distortion ◽  
Optical Coherence ◽  
Three Dimensional Imaging

Three-dimensional Anterior Segment Optical Coherence Tomography of Filtering Blebs After Trabeculectomy

2008 ◽  
Vol 17 (3) ◽  
pp. 193-196 ◽  
Author(s):  
Masahiro Miura ◽  
Keisuke Kawana ◽  
Takuya Iwasaki ◽  
Takahiro Kiuchi ◽  
Tetsuro Oshika ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Three Dimensional ◽  
Optical Coherence

scholarly journals Spectral optical coherence tomography findings in patients with ocular toxoplasmosis: A case series study

2020 ◽  
Vol 54 ◽  
pp. 125-128 ◽  
Author(s):  
Feriel Ammar ◽  
Ahmed Mahjoub ◽  
Nadia Ben Abdesslam ◽  
Leila Knani ◽  
Mohamed Ghorbel ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Case Series ◽  
Ocular Toxoplasmosis ◽  
Optical Coherence ◽  
Case Series Study ◽  
Spectral Optical Coherence Tomography ◽  
Series Study

Anterior Segment Optical Coherence Tomography Imaging in Peripheral Ulcerative Keratitis, a Corneal Structural Description

2020 ◽  
Author(s):  
Clemence BONNET ◽  
Louis Debillon ◽  
Saba Al-Hashimi ◽  
Florence Hoogewoud ◽  
Dominique Monnet ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Systemic Vasculitis ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Case Series ◽  
Structural Description ◽  
Optical Coherence ◽  
Peripheral Ulcerative Keratitis ◽  
The Mean ◽  
Ulcerative Keratitis

Abstract Background Anterior-segment optical coherence tomography (AS OCT) is an important tool, helpful to diagnose and manage many corneal conditions, but has not been reported in cases of peripheral ulcerative keratitis (PUK). The aim of this study is to describe AS OCT findings in cases of PUK. Methods Retrospective observational case series of six eyes with a PUK with proven systemic vasculitis. Clinical course, slit lamp photographs, and AS OCT findings were the main outcomes. Results The AS OCT findings were found to correlate with the ocular disease’s level of activity. In the acute stage, an absence of corneal epithelium, a scrambled appearance of the anterior stroma and a heterogeneous stromal reflectivity were observed. During the reduction of disease level activity, an irregular hyporeflective epithelium, a smoother anterior stroma, and a homogenous hyperreflective stroma were seen. At the healed stage, a filling of the corneal defect by a hyporeflective thick epithelium, the persistence of the hyperreflective underlying stroma, and a demarcation line were observed. The mean total corneal thickness at last follow-up was significantly thicker (509 ± 147 µm) compared with the mean corneal thickness at onset (408 ± 131 µm; P = 0.03). Conclusions AS OCT provides an assessment of structural changes occurring in PUK, useful for its diagnosis and monitoring.

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