Low-dose heparin prophylaxis of postoperative venous thrombosis: preparations and costs

1972 ◽  
Vol 10 (25) ◽  
pp. 100-100

Our article (November 10, p. 89) gave the basic NHS cost of a 7-day perioperative course (5000 i.u. 12-hourly) as 75 to 90p. MIMS gave the wrong price and in fact Weddel’s heparin costs the same as the other brands, and 75p. is the correct figure. It is worth noting that in the case of heparin, which is almost entirely used in hospitals, the actual cost is up to 25% less than the ‘basic NHS cost’, because most hospitals buy large quantities at special contract prices. The opposite is true for drugs dispensed by retail pharmacists, where the actual cost exceeds the basic NHS cost because it includes a dispensing fee and container allowance.

1988 ◽  
Vol 22 (2) ◽  
pp. 107-114 ◽  
Author(s):  
Andra J. Melamed ◽  
Jeanette Suarez

Deep venous thrombosis (DVT) is a significant problem in the postoperative course of high-risk patients. Risk factors that further predispose patients to DVT include obesity, age over 40 years, smoking, dehydration, and a prior history of thromboembolism. Diagnosis of DVT by physical examination and medical history is difficult; objective diagnostic techniques are often required. Considerable emphasis has been placed on the cost-effectiveness of implementing prophylactic measures in patients who are at high risk for developing DVT. Physical maneuvers attempt to reduce stasis and enhance venous return and pharmacologic approaches alter blood coagulability. The drug therapy used in preventing DVT consists of dextran, low-dose heparin, a combination of low-dose heparin and dihydroergotamine, and warfarin. Effective prophylactic regimens differ according to the type of patients at risk. Prophylactic therapy should be tailored according to the patient's disease and degree of risk.


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