Monitoring during Low-Dose Heparin Prophylaxis

1975 ◽  
Vol 293 (15) ◽  
pp. 776-776 ◽  
1972 ◽  
Vol 10 (25) ◽  
pp. 100-100

Our article (November 10, p. 89) gave the basic NHS cost of a 7-day perioperative course (5000 i.u. 12-hourly) as 75 to 90p. MIMS gave the wrong price and in fact Weddel’s heparin costs the same as the other brands, and 75p. is the correct figure. It is worth noting that in the case of heparin, which is almost entirely used in hospitals, the actual cost is up to 25% less than the ‘basic NHS cost’, because most hospitals buy large quantities at special contract prices. The opposite is true for drugs dispensed by retail pharmacists, where the actual cost exceeds the basic NHS cost because it includes a dispensing fee and container allowance.


The Lancet ◽  
1978 ◽  
Vol 311 (8056) ◽  
pp. 160-161
Author(s):  
O.J.S. Buruma ◽  
A.R. Wintzen ◽  
E. Briët

1989 ◽  
Vol 76 (9) ◽  
pp. 933-935 ◽  
Author(s):  
D. A. Taberner ◽  
L. Poller ◽  
J. M. Thomson ◽  
G. Lemon ◽  
F. J. Weighill

1985 ◽  
Vol 78 (2) ◽  
pp. 109-111 ◽  
Author(s):  
T K Day

Plasma heparin levels and operative/postoperative bleeding were assessed in 16 patients of varying body weights who received subcutaneous low-dose heparin prophylaxis for deep vein thrombosis during and after transurethral resection for benign prostatic hypertrophy. The concentration of heparin in the blood at operation and subsequently was found to vary widely but did not correlate with the extent of blood loss. When adjusted for body weight, plasma heparin concentration showed significantly less variation from patient to patient. In this respect, body weight was a more effective parameter than lean body mass or surface area. Adjustment of heparin dosage by body weight may be advisable when using low-dose heparin prophylaxis.


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