scholarly journals Comparison of maximal acid output and gastrin response to meals in Chinese and Scottish normal and duodenal ulcer subjects.

Gut ◽  
1980 ◽  
Vol 21 (4) ◽  
pp. 324-328 ◽  
Author(s):  
S K Lam ◽  
M Hasan ◽  
W Sircus ◽  
J Wong ◽  
G B Ong ◽  
...  
1968 ◽  
Vol 13 (11) ◽  
pp. 372-378 ◽  
Author(s):  
R. Hume ◽  
J. F. Adams

Maximal acid output (M.A.O.) and intrinsic factor (I.F.) of the stomach were measured in 16 patients with polycythaemia vera, 4 of whom had a duodenal ulcer and 2 pernicious anaemia. It was found that, in general, the M.A.O. was significantly less than normal unless an active duodenal ulcer was present when the M.A.O. would reach the usual levels for duodenal ulcer subjects. The gastric I.F. output showed a significant correlation with the M.A.O. These results are discussed in the light of the increased incidence of peptic ulcer in polycythaemia vera and the occasionally reported cases of polycythaemia vera and pernicious anaemia.


1985 ◽  
Vol 7 (5) ◽  
pp. 375-378 ◽  
Author(s):  
G Battaglia ◽  
R Farini ◽  
F Di Mario ◽  
F Vianello ◽  
A Piccoli ◽  
...  

Digestion ◽  
1968 ◽  
Vol 1 (2) ◽  
pp. 115-119
Author(s):  
H.G. Desai ◽  
A.V. Borkar ◽  
K.N. Jeejeebhoy

BMJ ◽  
1971 ◽  
Vol 2 (5757) ◽  
pp. 313-315 ◽  
Author(s):  
H. G. Desai ◽  
M. P. Zaveri ◽  
F. P. Antia

1972 ◽  
Vol 43 (2) ◽  
pp. 181-191
Author(s):  
J. B. Elder ◽  
G. Gillespie ◽  
E. H. G. Campbell ◽  
I. E. Gillespie ◽  
G. P. Crean ◽  
...  

1. The acid secretory responses to a range of small doses of pentagastrin in 0·15 m-NaCl have been studied in thirty-one preoperative duodenal ulcer subjects. Acid output increased significantly above basal values when a dose of 0·064 μg h−1 kg−1 was given. 2. Control observations in sixteen duodenal ulcer patients using the saline solvent alone at identical rates of infusion showed no significant increase in acid output. 3. From the dose-response curves sub-threshold and threshold doses of pentapeptide are suggested for duodenal ulcer patients before truncal vagotomy. 4. Considerable variation in acid response was noted between patients given the same body-weight dose of pentapeptide. The results suggest that a ‘twilight zone’ of stimulation exists between the dose of pentagastrin by which few patients are stimulated and the dose by which the majority are stimulated. This may reflect some variation in the sensitivity to stimulation by pentagastrin from one patient to another.


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