scholarly journals 36 Characteristics of cardiac arrest survivors subsequently diagnosed with long QT syndrome attending an inherited cardiac conditions clinic

2021 ◽  
Author(s):  
C Galvin ◽  
M Gallagher ◽  
H Cronin ◽  
T Prendiville ◽  
C McGorrian ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Long Qt Syndrome ◽  
Long Qt ◽  
Inherited Cardiac Conditions ◽  
Qt Syndrome

scholarly journals Prolonged QTc: "Mind the Gap"

2014 ◽  
Vol 2 (1) ◽  
pp. 44-45
Author(s):  
Ahmad Mursel Anam ◽  
Raihan Rabbani ◽  
Farzana Shumy ◽  
M Mufizul Islam Polash ◽  
M Motiul Islam ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Long Qt Syndrome ◽  
Qt Interval ◽  
Torsades De Pointes ◽  
Junior Doctors ◽  
Long Qt ◽  
Acquired Long Qt Syndrome ◽  
Prolonged Qt Interval ◽  
Prolonged Qt ◽  
Qt Syndrome

We report a case of drug induced torsades de pointes, following acquired long QT syndrome. The patient got admitted for shock with acute abdomen. The initial prolonged QT-interval was missed, and a torsadogenic drug was introduced post-operatively. Patient developed torsades de pointes followed by cardiac arrest. She was managed well and discharged without complications. The clinical manifestations of long QT syndromes, syncope or cardiac arrest, result from torsades de pointes. As syncope or cardiac arrest have more common differential diagnoses, even the symptomatic long QT syndrome are commonly missed or misdiagnosed. In acquired long QT syndrome with no prior suggestive feature, it is not impossible to miss the prolonged QT-interval on the ECG tracing. We share our experience so that the clinicians, especially the junior doctors, will be more alert on checking the QT-interval even in asymptomatic patients. DOI: http://dx.doi.org/10.3329/bccj.v2i1.19970 Bangladesh Crit Care J March 2014; 2 (1): 44-45

Lynch Syndrome and Long QT Syndrome – As If One Syndrome is Not Already Enough

2014 ◽  
Vol 10 (01) ◽  
pp. 25
Author(s):  
Ju Yee Lim ◽  
Barry Newell ◽  
Vivienne A Ezzat ◽  
Jens Samol ◽  
◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Lynch Syndrome ◽  
Long Qt Syndrome ◽  
Long Qt ◽  
Colon Cancers ◽  
First Case ◽  
Qt Syndrome ◽  
As If

A 51-year-old patient was treated with chemotherapy for two synchronous colon cancers and was diagnosed with Lynch syndrome. The patient also suffered a cardiac arrest and was also diagnosed with a long QT syndrome (LQTS) subsequently. This is the first case of a co-existence of Lynch syndrome and LQTS.

Abstract 17597: Quantitative T Wave Analysis Can Identify Patients With Symptomatic Long QT Syndrome

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Alan Sugrue ◽  
J. Martijn Bos ◽  
Vaclav Kremen ◽  
Bo Qiang ◽  
Paul A Friedman ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Long Qt Syndrome ◽  
Genetic Disorder ◽  
Practical Importance ◽  
Torsade De Pointes ◽  
Analysis Program ◽  
Wave Analysis ◽  
Long Qt ◽  
T Wave ◽  
Qt Syndrome

Introduction: Long QT syndrome (LQTS) is a genetic disorder associated with abnormal ventricular repolarization and a predisposition for torsade de pointes and sudden cardiac death. Identification of markers to elucidate high risk patients is of major practical importance. Our aim was to use a novel, automated quantitative T wave analysis program to distinguish symptomatic from asymptomatic LQTS patients. Methods: We analyzed a genotyped cohort of 420 patients (22 ± 15.7years, 43% male) with either LQT1 (61%) or LQT2 (39%). ECG analysis was conducted using novel software that we created to automatically detect subtle changes in T wave morphology. Symptomatic patients were defined as those with a history of syncope or resuscitated cardiac arrest that was suspected of being LQTS triggered. Classification was performed using the top three T wave features in a linear discriminant classifier by 10x10 cross-validation. Results: Symptomatic LQT1 patients have a greater QTc duration in lead aVF (437 msec vs 416 msec, p <0.0001), a greater T wave center of gravity on the x axis (COGx) in lead V2 (0.304 vs 0.280, p <0.0001) and longer Tpeak-Tend/QT in lead II (0.208 vs 0.188, p < 0.0001) than asymptomatic patients with LQT1. Use of these 3 features enabled classification of symptomatic status in 72% of LQT1 cases, compared to 68% when QTc was used to classify alone. Symptomatic LQT2 patients had a longer QTc in Lead 1 (460 vs 418 msec, p < 0.0001), COGx in 4th segment of T wave was greater in lead V5 (0.399 vs 0.350, p<0.0001), and the Tpeak-Tend interval in V2 was longer (126 vs 99 msec, P =0.0004). Use of these 3 features enabled correct classification in 73% of LQT2 cases, compared to 67% when QTc was used alone. Conclusions: Application of an automated T wave analysis program was able to identify T wave features that distinguished the patients who presented as symptomatic LQTS, associated with syncope or resuscitated cardiac arrest. Use of these features could help assess arrhythmic risk and guide management strategies for patients with LQTS.

scholarly journals A Hiccup in Hiccup Management: Cardiac Arrest from Previously Undiagnosed Congenital Long QT Syndrome

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Robert Hughes ◽  
Johnathan M. Sheele
Keyword(s):  
Cardiac Arrest ◽  
High Risk ◽  
Sudden Cardiac Death ◽  
Long Qt Syndrome ◽  
Cardiac Death ◽  
Long Qt ◽  
Congenital Condition ◽  
Qt Syndrome ◽  
Congenital Long Qt Syndrome

We report the case of a person who went into cardiac arrest after being given chlorpromazine for hiccups and was subsequently diagnosed with congenital Long QT Syndrome. Long QT Syndrome is an uncommon, congenital condition that carries a high risk of sudden cardiac death. Clinicians need to recognize the risk that chlorpromazine may prolong the QTc and prepare to manage potential complications.

Extreme QT prolongation during therapeutic hypothermia after cardiac arrest due to long QT syndrome

2012 ◽  
Vol 30 (4) ◽  
pp. 638.e5-638.e8 ◽  
Author(s):  
Nobuhiro Nishiyama ◽  
Toshiaki Sato ◽  
Yoshiyasu Aizawa ◽  
Satoshi Nakagawa ◽  
Hideaki Kanki
Keyword(s):  
Cardiac Arrest ◽  
Therapeutic Hypothermia ◽  
Long Qt Syndrome ◽  
Qt Prolongation ◽  
Long Qt ◽  
Qt Syndrome
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