scholarly journals 988 The impact of COVID-19 pandemic on gynecological and breast cancer detection rate: A tertiary center perspective

Author(s):  
K Knoll ◽  
E Reiser ◽  
I Tsibulak ◽  
K Leitner ◽  
J Kögl ◽  
...  
2021 ◽  
Author(s):  
Katharina Knoll ◽  
Elisabeth Reiser ◽  
Katharina Leitner ◽  
Johanna Kögl ◽  
Christoph Ebner ◽  
...  

Abstract Purpose: The aim of the present study was to assess the impact of postponed screening examinations and lockdown measures on gynecological and breast cancer detection rate throughout the year 2020 in a gynecological oncological center in Austria.Methods: Data of 889 patients with either newly diagnosed gynecological or breast cancer between January 2019 and December 2020 were collected. Clinical parameters including symptoms, performance status, comorbidities and referral status were compared in patients, who were newly diagnosed with cancer in the period of the first lockdown from March 2020 – April 2020 and the second lockdown from November 2020 – December 2020 and compared to the same period in 2019.Results: Our results showed a strong decline in newly diagnosed cancers during the lockdown periods: -45% in gynecological cancer and -52% in breast cancer compared to the same period in 2019. Compared to the analogue period of 2019, breast cancer patients reported significantly more tumor-associated symptoms (55% versus 31%, p=0.013) during and in between (48% versus 32%, p=0.022) the lockdowns. During the lockdown periods breast cancer patients were diagnosed with a significantly higher tumor-stage (T2-T4; p=0.047).Conclusion: Both lockdowns led to a strong decrease in newly diagnosed gynecological and breast cancers. Treatment delays in potentially curable disease could lead to inferior clinical outcomes, with the risk of missing the optimal treatment window. As the COVID-19 pandemic will be a challenge for some time to come, new strategies in patient care are needed to optimize cancer screening and management during the pandemic.


Radiology ◽  
2007 ◽  
Vol 243 (2) ◽  
pp. 360-367 ◽  
Author(s):  
Yulei Jiang ◽  
Diana L. Miglioretti ◽  
Charles E. Metz ◽  
Robert A. Schmidt

Author(s):  
Penghuan Qu ◽  
Xueou Liu ◽  
Yubei Huang ◽  
Ziwei Feng ◽  
Xin Wang ◽  
...  

Abstract Background To investigate whether women with benign breast disease (BBD) history have higher breast cancer detection rate in screening. Methods We reviewed data for 33 001 female participants in Multi-modality Independent Screening Trial (MIST). Corresponding data for 6823 breast cancer patients were retrieved from the Tianjin Breast Cancer Cases Cohort (TBCCC) and analyzed for comparison. Results The breast cancer detection rate was 2.83‰ among women with BBD history and 3.28‰ in women without. Moreover, the proportion of carcinoma in situ (CIS) was also lower in women with BBD history than women without (7.69 versus 20.31%). In contrast, analysis of TBCCC data revealed a higher proportion of CIS in patients with BBD history (5.05%) than patients without (3.26%). Our data showed that a larger proportion of women with BBD history had undergone previous breast examinations. Additionally, among participants diagnosed with both breast cancer and BBD in MIST, we found a lower proportion of CIS in women with BBD history (11.76%) compared to women without (32.14%). Conclusions Women with BBD history were not found to have higher detection rate in breast cancer screening. Women with BBD history were more likely to be proactive in seeking breast examinations and to have breast cancer be diagnosed in clinic.


2021 ◽  
Vol 5 ◽  
pp. AB005-AB005
Author(s):  
Jawad Ashraf ◽  
Peter McAnena ◽  
Ray Mclaughlin ◽  
Michael Kerin ◽  
Amir Aziz ◽  
...  

2014 ◽  
Vol 45 (12) ◽  
pp. 2497-2501 ◽  
Author(s):  
Benjamin C. Calhoun ◽  
Karinn Chambers ◽  
Teresa Flippo-Morton ◽  
Chad A. Livasy ◽  
Edward J. Armstrong ◽  
...  

2021 ◽  
Vol 19 (01) ◽  
pp. 109-116
Author(s):  
NORHASHIMAH MOHD NORSUDDIN ◽  
NURFADHILAH IDRIS

OBJEKTIF: Kajian ini dilakukan untuk mengenalpasti kategori densiti payudara yang mempunyai kebarangkalian tinggi untuk menyebabkan kanser payudara tidak dikesan atau disalah diagnosis. METODOLOGI: Kelulusan etika menjalankan penyelidikan telah diperolehi daripada Jawatankuasa Etika Penyelidikan Universiti Kebangsaan Malaysia. Sebanyak 495 kes mamografi telah dipilih dari Jabatan Radiologi, Pusat Perubatan Universiti Kebangsaan Malaysia. Semua kes mamografi telah diasingkan kepada 4 kumpulan diagnosis iaitu negative benar, positif benar, positif palsu dan negatif palsu. Kemudian, setiap kes mamografi dibahagikan mengikut empat kategori densiti payudara BI-RADS (I, II, III, IV). Analisis kebarangkalian risiko (odd ratio) setiap kategori densiti payudara dengan keputusan positif palsu dan negatif palsu dilakukan dengan menggunakan ujian regresi logistik. HASIL KAJIAN: Kebarangkalian imej mamografi dalam kategori densiti BI-RAD IV didiagnosis sebagai positif palsu adalah emapt kali ganda berbanding imej mamografi dalam kategori densiti BI-RAD I (odd ratio [OR], 4.27; 95% CI,0.88- 20.67). Manakala, imej mamografi yang mempunyai densiti BI-RAD II dan BI-RAD III mempunyai hampir dua kali ganda kemungkinan didiagnosis sebagai negatif palsu berbanding wanita berdensiti BI-RAD I (odd ratio [OR], 1.59, 1.32; 95% CI, 0.29-8.77, 0.25-7.01). KESIMPULAN: Densiti payudara dalam mamografi mempengaruhi keputusan diagnosis pakar radiologi dalam pengesanan kanser payudara. Kes mamografi yang mempunyai densiti BI-RAD IV lebih cenderung disalah diagnosis. Manakala pengesanan kanser dalam payudara berdensiti BI-RAD II dan BI-RAD III lebih berisiko untuk tidak dikesan. Penelitian yang lebih perlu diberikan dalam mentafsir imej mamografi berdensiti BI-RAD II, III dan IV bagi mengelakkan kanser disalah diagnosis atau tidak dikesan di peringkat awal. Pengesanan awal kanser payudara dapat meningkatkan kemandirian pesakit kanser.


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