scholarly journals Small blood vessel disease in allergic granulomatous angiitis (Churg-Strauss syndrome)

1989 ◽  
Vol 42 (9) ◽  
pp. 1001-1002 ◽  
Author(s):  
C Lichtig ◽  
R Ludatscher ◽  
E Eisenberg ◽  
E Bental
2005 ◽  
Vol 129 (6) ◽  
pp. e141-e143
Author(s):  
Kazuhiko Hayashi ◽  
Yasushi Horie ◽  
Hiroyuki Takahata ◽  
Youshin Adachi ◽  
Yukisato Kitamura ◽  
...  

Abstract Churg-Strauss syndrome, or allergic granulomatous angiitis, is an uncommon vasculitic syndrome. We describe a 53-year-old man with Churg-Strauss syndrome and subsequent opportunistic cytomegalovirus enterocolitis. During intensive care, including steroid-pulse therapy, the patient developed rapidly progressive anemia caused by active bleeding from his small intestine, resulting in resection of 20 cm of ileum. Diagnosis of Churg-Strauss syndrome was confirmed both by characteristic clinical features and by histology. Histologic examination also revealed multiple shallow ulcers accompanied by cytomegalovirus infection. Characteristic angiitis was found in the ileum with normal-like mucosa, and it was not necessarily associated with ileal ulcers. This finding suggests that cytomegalovirus infection may be one of the causes or exacerbating factors for ileal ulcers in Churg-Strauss syndrome, although ulcers of the intestine have usually been considered to be caused by ischemia resulting from angiitis.


Respiration ◽  
2000 ◽  
Vol 67 (5) ◽  
pp. 577-579 ◽  
Author(s):  
Hisako Matsumoto ◽  
Akio Niimi ◽  
Katsuhiro Suzuki ◽  
Mitsuru Kawai ◽  
Yasunori Matsui ◽  
...  

2004 ◽  
Vol 61 (3) ◽  
pp. 321-325
Author(s):  
Gordana Trifunovic ◽  
Goran Plavec ◽  
Ilija Tomic ◽  
Lidija Popovic ◽  
Dusan Stefanovic

Allergic granulomatous angiitis (AGA) - Churg-Strauss syndrome, is a rare autoimmune disease characterized by three distinct clinical phases prodromal, eosinophilic, and vasculitic, and most of respiratory symptoms and signs begin in the first two phases of the disease. Two female patients of different age, who fulfilled the diagnostic criteria for AGA, and were in different phases and with the different duration of the disease are presented. The first patient (24 years of age) was admitted to the hospital due to aggravation of asthma, heart failure, and polyneuropathy. The second one (45 years of age) was also hospitalized due to the worsening of asthma polyneuropathy, and fever. Both were treated continuously with glucocorticoids. The older patient also received a total of six pulse doses of cyclophosphamide. Satisfactory response to such a treatment was achieved in both cases.


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