scholarly journals The neurobehavioural rating scale-revised: sensitivity and validity in closed head injury assessment

2001 ◽  
Vol 71 (5) ◽  
pp. 643-651 ◽  
Author(s):  
S R McCauley
Keyword(s):  
Head Injury ◽  
Rating Scale ◽  
Closed Head Injury ◽  
Closed Head ◽  
Injury Assessment

Use of the Disability Rating Scale recovery curve as a predictor of psychosocial outcome following closed-head injury

2001 ◽  
Vol 7 (4) ◽  
pp. 457-467 ◽  
Author(s):  
STEPHEN R. McCAULEY ◽  
H. JULIA HANNAY ◽  
PAUL R. SWANK
Keyword(s):  
Head Injury ◽  
Cognitive Deficits ◽  
Rating Scale ◽  
Closed Head Injury ◽  
Post Injury ◽  
Recovery Curve ◽  
Disability Rating Scale ◽  
Closed Head ◽  
Rate Of Recovery ◽  
Disability Rating

Rapid rate of recovery has been associated with better outcome following closed-head injuries, but few studies have compellingly demonstrated this. This study used growth curve analyses of Disability Rating Scale (DRS) scores at acute hospitalization discharge, 1, 3, and 6 months post injury in a sample of 55 patients with a closed-head injury. Six month post-injury outcome measures were taken from significant other (SO) responses on the NYU Head Injury Family Interview (NYU-HIFI) including severity and burden ratings of affective/neurobehavioral disturbance, cognitive deficits, and physical/dependency status. Rate of recovery (linear and curvilinear recovery curve components) was significantly related to the level of affective/neurobehavioral severity, and the severity and burden of SO-perceived cognitive deficits. Only the intercept of the DRS recovery curve was associated with the SO-perceived severity and burden of physical/dependency status. Growth curve modeling is a meaningful and powerful tool in predicting head injury outcome. (JINS, 2001, 7, 457–467.)

How useful is the WAIS-R in closed head injury assessment?

1992 ◽  
Vol 48 (2) ◽  
pp. 219-225 ◽  
Author(s):  
Christopher E. Paniak ◽  
Kim Silver ◽  
M. Alan J. Finlayson ◽  
Lawrence P. Tuff
Keyword(s):  
Head Injury ◽  
Closed Head Injury ◽  
Closed Head ◽  
Injury Assessment

Closed Head Injury Assessment and Research Methodology

1994 ◽  
Vol 26 (1) ◽  
pp. 24-29 ◽  
Author(s):  
Thomas E. Sullivan ◽  
Bruce K. Schefft ◽  
Joel S. Warm ◽  
William N. Dember
Keyword(s):  
Head Injury ◽  
Research Methodology ◽  
Closed Head Injury ◽  
Closed Head ◽  
Injury Assessment

The Management of Minor Closed Head Injury in Children

PEDIATRICS ◽  
2000 ◽  
Vol 106 (6) ◽  
pp. 1524-1525 ◽  
Author(s):  
C. M. A. LeBlanc; ◽  
J. B. Coombs ◽  
R. Davis
Keyword(s):  
Head Injury ◽  
Closed Head Injury ◽  
Closed Head

Management of Minor Closed Head Injury in Children

PEDIATRICS ◽  
2001 ◽  
Vol 107 (5) ◽  
pp. 1231-1231 ◽  
Author(s):  
A. J. Smally; ◽  
J. B. Coombs ◽  
R. Davis
Keyword(s):  
Head Injury ◽  
Closed Head Injury ◽  
Closed Head

scholarly journals Differential Leukocyte and Platelet Profiles in Distinct Models of Traumatic Brain Injury

Cells ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 500
Author(s):  
William Brad Hubbard ◽  
Meenakshi Banerjee ◽  
Hemendra Vekaria ◽  
Kanakanagavalli Shravani Prakhya ◽  
Smita Joshi ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Head Injury ◽  
Closed Head Injury ◽  
Diffuse Brain Injury ◽  
Blood Brain ◽  
Closed Head ◽  
Leukocyte Counts ◽  
Neutrophil Aggregation ◽  
Blood Leukocyte

Traumatic brain injury (TBI) affects over 3 million individuals every year in the U.S. There is growing appreciation that TBI can produce systemic modifications, which are in part propagated through blood–brain barrier (BBB) dysfunction and blood–brain cell interactions. As such, platelets and leukocytes contribute to mechanisms of thromboinflammation after TBI. While these mechanisms have been investigated in experimental models of contusion brain injury, less is known regarding acute alterations following mild closed head injury. To investigate the role of platelet dynamics and bioenergetics after TBI, we employed two distinct, well-established models of TBI in mice: the controlled cortical impact (CCI) model of contusion brain injury and the closed head injury (CHI) model of mild diffuse brain injury. Hematology parameters, platelet-neutrophil aggregation, and platelet respirometry were assessed acutely after injury. CCI resulted in an early drop in blood leukocyte counts, while CHI increased blood leukocyte counts early after injury. Platelet-neutrophil aggregation was altered acutely after CCI compared to sham. Furthermore, platelet bioenergetic coupling efficiency was transiently reduced at 6 h and increased at 24 h post-CCI. After CHI, oxidative phosphorylation in intact platelets was reduced at 6 h and increased at 24 h compared to sham. Taken together, these data demonstrate that brain trauma initiates alterations in platelet-leukocyte dynamics and platelet metabolism, which may be time- and injury-dependent, providing evidence that platelets carry a peripheral signature of brain injury. The unique trend of platelet bioenergetics after two distinct types of TBI suggests the potential for utilization in prognosis.

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