The Relationship of the Gonococcal Complement Fixation Test to the Diagnosis and Treatment of Gonorrh a Discussion

SummaryThe relationship between the serological findings for brucellosis and the epidemiological factors has been studied in veterinary surgeons in Northern Ireland. The anti-human globulin (Coombs) test and the complement-fixation test for brucella were used in two groups of veterinary surgeons, those self-employed and those employed by the Ministry of Agriculture.Significant serological differences were found to exist between the two groups. Those in private practice showed changes related to age, cattle skin rash, reactions to S. 19 vaccine accidents and symptoms suggestive of brucellosis in the past or the last year. But those working for the Ministry only showed titre changes related to the length of their private practice experience before joining the Ministry. In neither group was there a relationship between serological findings and the type of milk drunk or any particular group of symptoms suggestive of brucellosis.The findings indicate that high titres to brucella by the Coombs and complement-fixation test can occur in people repeatedly exposed to infection at work. Titres which would be of diagnostic importance in the rest of the population may be of little diagnostic significance even when they are as high as 160 Coombs and 128 complement fixation.

Download Full-text

Evaluation of the Complement Fixation Test in Amebiasis

Gastroenterology ◽

10.1016/s0016-5085(52)80038-1 ◽

1952 ◽

Vol 21 (3) ◽

pp. 391-399 ◽

Cited By ~ 1

Author(s):

Elwood Buchman ◽

Harold J. Kullman ◽

George F. Margonis

Keyword(s):

Complement Fixation Test ◽

Complement Fixation ◽

Fixation Test

Download Full-text

IMMUNOASSAY OF GONADOTROPHINS USING COMPLEMENT FIXATION

Acta Endocrinologica ◽

10.1530/acta.0.062s113 ◽

1969 ◽

Vol 62 (1_Suppl) ◽

pp. S113-S133 ◽

Cited By ~ 2

Author(s):

Sam Brody

Keyword(s):

Complement Fixation Test ◽

Complement Fixation ◽

Research Work ◽

Fixation Test ◽

Years Of Experience ◽

Standard Practice ◽

Clinical Observations ◽

Technical Procedure ◽

Methodological Problems

ABSTRACT This report is a summary of 10 years of experience with the complement fixation test as adopted for the immunoassay of HCG in serum. It is based on published as well as unpublished material. The discussion centers mainly around methodological problems, criteria of reliability, and clinical observations. It is our impression that the complement fixation test is a reasonably rapid and simple technical procedure. It is standard practice in every bacteriological and virological laboratory. The precision of the HCG assay is high. Its accuracy is good. The complement fixation assay, as reported here, fulfils the criteria of specificity. It has been evaluated by means of serological techniques and through comparison between biopotency and immunopotency of HCG in serum with reference to a common standard. Its application for routine as well as research work is illustrated.

Download Full-text

Rapid detection of Chlamydia/Chlamydophila group in samples collected from swine herds with and without reproductive disorders

Polish Journal of Veterinary Sciences ◽

10.2478/pjvs-2014-0052 ◽

2014 ◽

Vol 17 (2) ◽

pp. 367-369 ◽

Cited By ~ 3

Author(s):

K. Rypula ◽

A. Kumala ◽

P. Lis ◽

K. Niemczuk ◽

K. Płoneczka-Janeczko ◽

...

Keyword(s):

Real Time ◽

Real Time Pcr ◽

Rapid Detection ◽

Complement Fixation Test ◽

Complement Fixation ◽

Fixation Test ◽

Reproductive Disorders ◽

Serum Samples ◽

Swine Herds

Abstract The study was carried out in seven reproductive herds of pigs. In three of them reproductive disorders were observed. Three herds consisted of 10-50 and four consisted of 120-500 adult sows and they were called small and medium, respectively. Fifty-seven adult sows were randomly selected from herds. Serum samples were tested using the complement fixation test and swabs from both eyes and from the vaginal vestibule were examined using real-time PCR. All serum samples were negative. Infected sows were present in each of the study herds. In total, there were 28 positive samples (53%, 28/48) in real-time PCR in sows with reproductive disorders and 35 (53%, 35/66) in sows selected from herds without problems in reproduction. One isolate proved to be Chlamydophila pecorum, whereas all the remaining were Chamydia suis

Download Full-text