RÉSISTANCE COMPARÉE DES VIRUS POLIOMYÉLITIQUE, HERPÉTIQUE, SPUMEUX ET SV-40 À L"ACIDITÉ

Poliovirus suspensions of different types and strains, as well as vacuolating virus (SV-40) and human herpes virus, were adjusted to various points between pH 8.5 and pH 1.5. The comparative inactivation of these viruses was established for different conditions of temperature and time of treatment. There appeared to be a large enough difference in the resistance of the poliovirus group on the one hand and that of herpes and vacuolating virus on the other to permit a selective inactivation of these last-mentioned viruses in contaminated suspensions of poliovirus. A few assays done with foamy virus showed that this selective inactivation could be applied also to poliovirus suspensions contaminated with this agent.This simple technique could be of help in the preparation of poliomyelitis vaccine, live or inactivated.