Enterotoxin B formation by fermentation mutants of Staphylococcus aureus

1976 ◽  
Vol 22 (2) ◽  
pp. 182-188
Author(s):  
Robert A. Altenbern

An appreciable fraction of carbohydrate-negative (car) mutants of Staphylococcus aureus strains ATCC 14458,778, and S-6 exhibit increased enterotoxin B (SEB) production. In addition, some lac and mtl mutants of these strains also display enhanced SEB formation. All such mutants appear to be point mutations. Mutagen-induced reversions of high SEB producing car, mtl, or lac mutants yield varying amounts of SEB and some clones seem to be restored to the characteristics of the parent type. A few sequentially isolated lac, mtl double mutants of strain 778 elaborate much more or much less SEB than either the lac or the mtl single mutants.

1970 ◽  
Vol 1 (2) ◽  
pp. 169-173
Author(s):  
Joyce K. Czop ◽  
Merlin S. Bergdoll

After prolonged treatment with methicillin and penicillin, L-forms were prepared from 12 of 22 strains of Staphylococcus aureus . These L-forms were obtained from five of nine strains which produced enterotoxin A, from three of six strains that produced enterotoxin B, and from three of six strains that produced enterotoxin C. An L-form was also prepared from S. aureus strain AH, which produces both enterotoxins A and C. The synthesis of enterotoxin A by parent strains was least affected by the conditions required for L-form growth. Detectable amounts of enterotoxin A were produced by all of the revertants tested and by five of the six L-forms which were derived from type A-producing cells. Detectable amounts of enterotoxin B were produced by four of the five revertants but by none of the L-forms derived from type B-producing cells. Revertants and L-forms from cells which produced enterotoxin C did not produce enough enterotoxin C to be detectable on microslides.


1972 ◽  
Vol 24 (4) ◽  
pp. 561-566 ◽  
Author(s):  
Glynn G. Dietrich ◽  
Robert J. Watson ◽  
Gerald J. Silverman

1973 ◽  
Vol 25 (5) ◽  
pp. 770-773
Author(s):  
Joseph F. Metzger ◽  
Anna D. Johnson ◽  
William S. Collins ◽  
Virginia McGann

Sign in / Sign up

Export Citation Format

Share Document