Friedel–Crafts alkylation of benzene with 1,1-d2-1-chloropropane

1970 ◽  
Vol 48 (5) ◽  
pp. 858-862 ◽  
Author(s):  
C. C. Lee ◽  
D. J. Woodcock
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Spectral Data ◽  
Reaction Medium ◽  
Side Chain ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Alkylation Of Benzene ◽  
Nuclear Magnetic

The AlCl3 catalyzed reaction of 1,1-d2-1-chloropropane with benzene was carried out in excess benzene at about 5° or in 1,2,4-trichlorobenzene as solvent at 0°. The products, n-propylbenzene and isopropylbenzene, were examined by nuclear magnetic resonance and mass spectrometry. The results indicated only very minor amounts of isotope position scrambling in the propyl side chain, suggesting no major involvement of protonated cyclopropane intermediates in the reaction. The mass spectral data, however, demonstrated that the products are quite labile in the reaction medium, with extensive intermolecular hydride and deuteride transfers taking place.

scholarly journals N-[2-(1H-Indol-3-yl)ethyl]-2-(4-isobutylphenyl)propanamide

Molbank ◽  
10.3390/m1031 ◽  
2018 ◽  
Vol 2018 (4) ◽  
pp. M1031
Author(s):  
Stanimir Manolov ◽  
Iliyan Ivanov ◽  
Yulian Voynikov
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Spectral Data ◽  
1H Nmr ◽  
13C Nmr ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Nuclear Magnetic

The compound in the title was prepared by reaction between tryptamine and ibuprofen using N,N′-dicyclohexylcarbodiimide as a “dehydrating” reagent. The structure of the newly synthesized compound was determined by nuclear magnetic resonance (NMR) (1H-NMR and 13C-NMR), UV, IR, and mass spectral data.

High-throughput microcomputer-based binary-coded search systems for infrared, carbon-13 nuclear magnetic resonance, and mass spectral data

1982 ◽  
Vol 54 (11) ◽  
pp. 1772-1777 ◽  
Author(s):  
Alan P. Uthman ◽  
Jerry P. Koontz ◽  
Judy. Hinderliter-Smith ◽  
W. Stephen. Woodward ◽  
Charles N. Reilley
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Spectral Data ◽  
High Throughput ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Nuclear Magnetic ◽  
Search Systems

Eine ungewöhnliche intramolekulare Photoreaktion eines Hexachlorhexahydromethanonaphthalins / An Unusual Intramolecular Photoreaction of a Hexachlorohexahydromethanonaphthaline

1978 ◽  
Vol 33 (12) ◽  
pp. 1563-1564
Author(s):  
H. Parlar
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Infrared Spectroscopy ◽  
Magnetic Resonance ◽  
Spectral Data ◽  
Column Chromatography ◽  
Nuclear Magnetic

Photoreactions of 2-exo-bromo-5,6,7,8,9,9- hexachloro-1,2,4 a, 5,8,8 a-hexahydro-5,8-methanonaphthaline (1) were studied in the presence of acetophenone. With the help of column chromatography an unusual isomerisation product (3) was isolated, whose structure was established by spectral data obtained by mass spectrometry, infrared spectroscopy, and 1H nuclear magnetic resonance measurements.

scholarly journals Curcinomarcoide, a Novel Limonoid From Trichilia hirta (Meliaceae)—Complete 1H and 13C Chemical Shift Assignments

2019 ◽  
Vol 14 (5) ◽  
pp. 1934578X1984361
Author(s):  
Milena G. Curcino Vieira ◽  
Raimundo Braz Filho ◽  
Ivo. J. Curcino Vieira
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Chemical Shift ◽  
Spectral Data ◽  
Chemical Shift Assignments ◽  
13C Chemical Shift ◽  
Nuclear Magnetic

A novel limonoid named curcinomarcoide (1) was isolated from Trichilia hirta and characterized on the basis of its nuclear magnetic resonance and mass spectrometry spectral data and comparison with literature data.

scholarly journals Isocoproporphyrin: nuclear-magnetic-resonance- and mass-spectral methods for the determination of porphyrin structure

1973 ◽  
Vol 131 (2) ◽  
pp. 429-432 ◽  
Author(s):  
M. S. Stoll ◽  
G. H. Elder ◽  
D. E. Games ◽  
P. O'Hanlon ◽  
D. S. Millington ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Spectral Methods ◽  
Reductive Alkylation ◽  
New Techniques ◽  
Mass Spectral ◽  
Shift Reagents ◽  
Nuclear Magnetic

The use of ‘shift reagents’ in the determination of n.m.r. spectra, and of reductive alkylation in combination with g.l.c.–mass spectrometry, facilitates assignment of the order of substituents in porphyrins, and the application of these new techniques to isocoproporphyrin is described.

Notizen: Eine nicht erwartete intramolekulare Photoreaktion eines Hexachloroctahydrodimethanonaphthalins/An Unexpected Intramolecular Photoreaction of a Hexachlorooctahydrodimethanonaphthaline

1981 ◽  
Vol 36 (1) ◽  
pp. 125-126 ◽  
Author(s):  
H. Parlar ◽  
Y. Inanici
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Infrared Spectroscopy ◽  
Magnetic Resonance ◽  
Spectral Data ◽  
Column Chromatography ◽  
Nuclear Magnetic

Abstract Photoreactions of 1,2,3,4,10,10-hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4-endo, endo-5,8-dimethano-naphthaline (1) were studied in acetone with wavelengths above 290 nm. With the help of column chromatography an unusual isomerisation product (4) could be isolated, whose structure was established by spectral data obtained by mass spectrometry infrared spectroscopy, 1H and 13C nuclear magnetic resonance measurements.

Synthesis and 13C nuclear magnetic resonance spectral analysis of some diterpenoids related to the cleistanthane type hydrocarbon isolated from Amphibolisantarctica

1987 ◽  
Vol 65 (9) ◽  
pp. 2024-2026 ◽  
Author(s):  
Teodoro S. Kaufman ◽  
Mirta P. Mischne ◽  
Manuel Gonzalez-Sierra ◽  
Edmundo A. Ruveda
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Spectral Analysis ◽  
Magnetic Resonance ◽  
Natural Product ◽  
Spectral Data ◽  
Side Chain ◽  
13C Nuclear Magnetic Resonance ◽  
Related Compounds ◽  
Nuclear Magnetic

The synthesis of the cleistanthane-type diterpene 13 (8-β(H), 14-β-ethyl, 13-methylene podocarpane), a dihydro epimer of the natural product 6, is described. By comparison of the 13C nuclear magnetic resonance spectral data of 13 and related compounds with those reported for 6, the stereochemistry of the C-14 side chain of the latter was confirmed.

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