Polybrominated derivatives of 5α-androstane and 5α-estrane 3-ketones: cyclopropanol formation
Keyword(s):
Bromohydrin acetates from sodium borohydride reduction of di- and tribrominated 17β-hydroxy-5α-androstan-3-one and 17β-hydroxy-5α-estran-3-one have been prepared and their structures determined by spectroscopic methods. Some 220 MHz proton magnetic resonance data are reported for structure determination. The formation of cyclosteroid derivatives by 1,3-elimination of bromine with zinc–copper couple is discussed.
1967 ◽
Vol 71
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pp. 3954-3959
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1970 ◽
Vol 40
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pp. 179-185
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1968 ◽
Vol 90
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pp. 4583-4585
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1993 ◽
Vol 28
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pp. 329-332
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1973 ◽
Vol 51
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pp. 2571-2577
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1965 ◽
Vol 6
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pp. 4515-4522
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