Magnetic Resonance Data
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Author(s):  
Oleksandr S. Stychynskyi ◽  
Pavlo O. Almiz ◽  
Alina V. Topchii

The work is dedicated to the issue of atrial cardiomyopathies (ACs). They have a significant effect on the heart function, provoke rhythm disturbances and increase the risk of thromboembolic complications. The aim. To analyze the latest publications on the topic. The material for the analysis were the papers published by the leading arrhythmological clinics. Discussion. This paper describes the origin of the term “atrial cardiomyopathy”, highlights the conditional classification of changes in the atrial myocardium according to the EHRAS classification. The causes of this nosological form may be some types of gene mutations, as well as hypertension, congestive circulatory failure, diabetes mellitus, myocarditis, etc. ACs play an important role in the occurrence of atrial fibrillation (AF) and also affect its natural course and treatment outcomes. Electroanatomical mapping and magnetic resonance data show significant fibrotic changes in the atria in individuals with this form of arrhythmia. The DECAAF study (Delayed enhancement MRI and atrial fibrillation catheter ablation) showed that fibrotic changes in the atrial myocardium are directly related to the frequency of recurrent arrhythmias after catheter ablation. The DECAAFII study confirmed the effectiveness of the influence on the fibrous substrate in the catheter treatment of AF at stages 1 and 2 of fibrosis. The results of catheter treatment depend on the severity of fibrosis, which shows the importance of taking this factor into account when determining the indications for ablation. Conclusions. Thus, AC is an important component of the pathogenesis of AF. Improvement of techniques for influencing the fibrous substrate will improve the results of catheter treatment of AF.


Author(s):  
Handan Soysal ◽  
Niyazi Acer ◽  
Meltem Özdemir ◽  
Önder Eraslan

Abstract Objective The aim of this study is to measure the average corpus callosum (CC) volume of healthy Turkish humans and to analyze the effects of gender and age on volumes, including the genu, truncus, and splenium parts of the CC. Patients and Methods Magnetic resonance imaging brain scans were obtained from 301 healthy male and female subjects, aged 11 to 84 years. The median age was 42 years (min–max: 11–82) in females and 49 years (min–max: 12–84) in males. Corpus callosum and its parts were calculated by using MRICloud. CC volumes of each subject were compared with those of the age and gender groups. Results All volumes of the CC were significantly higher in males than females. All left volumes except BCC were significantly higher than the right volumes in both males and females. The oldest two age groups (50–69 and 70–84 years) were found to have higher bilateral CC volumes, and bilateral BCC volumes were also higher than in the other two age groups (11–29 and 30–49 years). Conclusion The results suggest that compared with females/males, females have a faster decline in the volume of all volumes of the CC. We think that quantitative structural magnetic resonance data of the brain is vital in understanding human brain function and development.


Analytica ◽  
2021 ◽  
Vol 2 (3) ◽  
pp. 50-56
Author(s):  
Jean-Marc Nuzillard

The recent revival of the study of organic natural products as renewable sources of medicinal drugs, cosmetics, dyes, and materials motivated the creation of general purpose structural databases. Dereplication, the efficient identification of already reported compounds, relies on the grouping of structural, taxonomic and spectroscopic databases that focus on a particular taxon (species, genus, family, order, etc.). A set of freely available python scripts, CNMR_Predict, is proposed for the quick supplementation of taxon oriented search results from the naturaL prOducTs occUrrences database (LOTUS, lotus.naturalproducts.net) with predicted carbon-13 nuclear magnetic resonance data from the ACD/Labs CNMR predictor and DB software (acdlabs.com) to provide easily searchable databases. The database construction process is illustrated using Brassica rapa as a taxon example.


BioResources ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. 4081-4092
Author(s):  
Roderquita K. Moore ◽  
Roland Gleisner ◽  
Carl J. Houtman

A desire to develop biorenewable materials has led to lactide–caprolactone copolymers being used in adhesive, medical, and pharmaceutical products. Use of this alternative material may diminish human impact on the environment and create products that are biocompatible. One advantage of these materials compared with other typical petroleum-based polymers is that they are easily degraded by microorganisms. In this study, the biodegradation of representative lactide–caprolactone macromonomers and an acrylic pressure sensitive adhesive incorporating these macromonomers was followed by a respirometric method using a consortium of microorganisms found in a typical wastewater treatment facility. The weight loss data of lactide–caprolactone macromonomers showed that the lowest molecular weight macromonomers with a high percentage of lactide had the greatest weight loss, which could have been caused by the greater number of ester linkages. Proton nuclear magnetic resonance data showed that for lower molecular weight copolymers, there was a preferential loss of caprolactone. Promisingly, testing of the full acrylic adhesives showed that they were easily degraded and thus provided a route to more environmentally friendly adhesive products.


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