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2012 ◽  
Vol 16 (07) ◽  
pp. 32-44

Growing Cord Blood Cells for Cancer Patients. Umbilical Cord Blood Transplantation in Adults - The Debate between One vs. Two Units. Stem Cells in Umbilical Cord. Cord Blood Banking - To Go Public or Stay Private.

Blood ◽  
2005 ◽  
Vol 105 (10) ◽  
pp. 3786-3792 ◽  
Author(s):  
Karen K. Ballen

Abstract Since the first report of a successful umbilical cord blood transplantation in 1988, there has been great interest in the use of cord blood as an alternative stem cell source to treat cancer and genetic diseases. More than 4000 cord blood transplantations have been performed worldwide. In this review, the scientific rationale for this therapy, as well as related preclinical studies, cord blood banking issues, and ethical concerns, will be addressed. Results of studies in both pediatric and adult transplantation will be discussed. Finally, new indications for cord blood use and emerging technologies will be addressed.


Author(s):  
Stephanie Vairy ◽  
Isabelle Louis ◽  
Marie-France Vachon ◽  
Johanne Richer ◽  
Pierre Teira ◽  
...  

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