scholarly journals Quantification of effects of mean blood pressure and left ventricular mass on noninvasive fast fractional flow reserve

2020 ◽  
Vol 319 (2) ◽  
pp. H360-H369
Author(s):  
Jun-Mei Zhang ◽  
Gaurav Chandola ◽  
Ru-San Tan ◽  
Ping Chai ◽  
Lynette L. S. Teo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Left Ventricular Mass ◽  
Fractional Flow Reserve ◽  
Disease Diagnosis ◽  
Left Ventricular ◽  
Mean Blood Pressure ◽  
Patient Specific ◽  
Fractional Flow ◽  
Flow Reserve ◽  
Ventricular Mass

While brachial mean blood pressure (MBP) and left ventricular mass (LVM) measured from CTCA are the two CFD simulation input parameters, their effects on noninvasive fractional flow reserve (FFRB) have not been systematically investigated. We demonstrate that inaccurate MBP and LVM inputs differing from patient-specific values could result in misclassification of borderline ischemic lesions. This is important in the clinical application of noninvasive FFR in coronary artery disease diagnosis.

scholarly journals TCT-386 Ethnic differences in coronary luminal volume, left ventricular mass and CT-derived fractional flow reserve

2018 ◽  
Vol 72 (13) ◽  
pp. B156
Author(s):  
Abdul Rahman Ihdayhid ◽  
Daniel Adams ◽  
Markus Goeller ◽  
Damini Dey ◽  
Udit Thakur ◽  
...  
Keyword(s):  
Left Ventricular Mass ◽  
Ethnic Differences ◽  
Fractional Flow Reserve ◽  
Left Ventricular ◽  
Fractional Flow ◽  
Flow Reserve ◽  
Ventricular Mass

scholarly journals 1120-64 High left ventricular mass does not limit the utility of fractional flow reserve for the physiologic assessment of lesion severity

2004 ◽  
Vol 43 (5) ◽  
pp. A76
Author(s):  
Adnan K Chhatriwalla ◽  
Kurt G Barringhaus ◽  
Michael Ragosta ◽  
Eric R Powers ◽  
J.Christopher McClish ◽  
...  
Keyword(s):  
Left Ventricular Mass ◽  
Fractional Flow Reserve ◽  
Left Ventricular ◽  
Fractional Flow ◽  
Flow Reserve ◽  
Ventricular Mass ◽  
Lesion Severity

Abstract 432: Race Differences in the Relationship between Urinary ET-1 and BP-related Target Organ Damage in Youth

Hypertension ◽  
2012 ◽  
Vol 60 (suppl_1) ◽  
Author(s):  
Gregory A Harshfield ◽  
Gregory A Harshfield ◽  
Jennifer Pollock ◽  
David Pollock
Keyword(s):  
Blood Pressure ◽  
Left Ventricular Mass ◽  
Target Organ Damage ◽  
Albumin Excretion Rate ◽  
Organ Damage ◽  
Left Ventricular ◽  
Target Organ ◽  
Related Target ◽  
Ventricular Mass ◽  
Lv Mass

The overall goal of this study was to determine race/ethnic differences in the associations between renal ET-1 and indices of blood pressure-related target organ damage in healthy adolescents. The subjects ranged in age between 15-19 years, had no history of any disease, and were not on any prescription medications. The 92 subjects consisted of 48 Caucasians (CA) and 44 African-Americans (AA). The two groups were similar with respect to height, weight, body mass index, blood pressure, ET-1), albumin excretion rate (AER), and left ventricular mass). Results: The CA’s were slightly older 17±1 v 16±1 (p=.02). The protocol was preceded by a 3 day self-selected sodium controlled diet of 250 mEq/day day which the subject picked up each day. The test day began with an echocardiogram for the assessment of left ventricular mass. Next, the subjects were seated for 60 minutes of rest during which the subjects consumed 200 ml of water. This was followed by the collection of a urine sample for the measurement of ET-1 and AER. Overall, ET-1 excretion was correlated with AER (r=.278), LV mass/ht 2.7 (r=.341), and systolic blood pressure (SBP; r=.365; p=.01 for each). The significant overall correlations were the result of significant correlations in AAs for AER (r=.344; p=.05), LV mass/ht 2.7 (r=.520; p=.01), and SBP (r=.645; p=.01) which were not apparent in CA’s. These findings suggest urinary ET-1 contributes to the development of BP-related target organ damage in AA youths prior to the development of increases in blood pressure.

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