Cardiac adrenergic innervation after instrumentation of the coronary artery in dog

1984 ◽  
Vol 246 (3) ◽  
pp. H459-H465 ◽  
Author(s):  
S. Dolezel ◽  
M. Gerova ◽  
B. Hartmannova ◽  
M. Dostal ◽  
H. Janeckova ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Left Coronary Artery ◽  
Surgical Intervention ◽  
Adrenergic Innervation ◽  
Histochemical Technique ◽  
Perivascular Nerves ◽  
Ramus Interventricularis Anterior

A fine methacrylate ring (not constricting the artery) was placed around the ramus interventricularis anterior (RIA) of the left coronary artery in dogs. By means of Falck's histochemical technique an extensive degeneration of the vasomotor and cardiomotor adrenergic innervation of ventricles was detected 14 days after the procedure. The innervation of atria remained intact. The surgical intervention as well as the scarring process (which compressed the conducting parts of axons composing the perivascular nerves) induced the degeneration. The results have important implications for experiments with instrumented arteries.

Pre-operative identification of an anomalous left coronary artery from the pulmonary artery in association with tetralogy of Fallot and an aortopulmonary window

2013 ◽  
Vol 24 (1) ◽  
pp. 170-171 ◽  
Author(s):  
Colin J. McMahon ◽  
Terence Prendiville ◽  
Lars Nolke
Keyword(s):  
Coronary Artery ◽  
Pulmonary Artery ◽  
Tetralogy Of Fallot ◽  
Left Coronary Artery ◽  
Surgical Intervention ◽  
Aortopulmonary Window ◽  
Anomalous Left Coronary Artery ◽  
Arterial Anomaly ◽  
Operative Assessment ◽  
Anomalous Left Coronary

AbstractA newborn baby girl was diagnosed with tetralogy of Fallot and an aortopulmonary window. At 3 weeks of age, the coexistent diagnosis of an anomalous left coronary artery from the pulmonary artery was made. Initial surgical intervention included a Takeuchi baffle of the left coronary artery, closure of the aortopulmonary window, and placement of a right Blalock–Taussig shunt. Complete repair was undertaken at 12 months of age. Close pre-operative assessment of the coronary arterial anomaly is crucial in patients with an aortopulmonary window and tetralogy of Fallot.

scholarly journals Anomalous Left Coronary Artery from the Pulmonary Artery: The Role of Multimodal Imaging—A Case Report

2020 ◽  
Vol 10 (2) ◽  
pp. 25-32
Author(s):  
Mita Singh ◽  
Ana Teresa Gomes ◽  
Moad El-Haddad ◽  
Abdel Khalid Saidmeerasah ◽  
Rashid Iqbal
Keyword(s):  
Case Report ◽  
Coronary Artery ◽  
Pulmonary Artery ◽  
Multimodal Imaging ◽  
Left Coronary Artery ◽  
Surgical Intervention ◽  
Collateral Flow ◽  
Anomalous Left Coronary Artery ◽  
Anomalous Left Coronary

Anomalous Left Coronary Artery from the Pulmonary Artery (ALCAPA) is a rare coronary artery anomaly which accounts for 0.25–0.5% of all congenital cardiac diseases, where most die within the first year of life. We present a case report of a 50-year-old lady who presented to hospital with persistent palpitations. Her admission electrocardiogram found her to be in Atrial Fibrillation (AF). She was rate-controlled and subsequently discharged. Despite that, she represented with further episodes of AF and was referred for an outpatient transthoracic echocardiogram. This revealed a dilated right coronary artery, retrograde flow in the left coronary artery and collateral flow in the myocardium. To investigate, the patient had undergone further imaging which confirmed the diagnosis. As such, she was later shortlisted for surgical intervention. Conclusively, our case exemplifies the role of multimodal imaging to identify the features of ALCAPA and may be useful for the purposes of surgical intervention.

Scintigraphic Detection of Experimental Myocardial Infarction with 99mTc-Heparin in the Dog

1985 ◽  
Vol 24 (03) ◽  
pp. 111-114 ◽  
Author(s):  
P. Kafka ◽  
J. Kubíček ◽  
J. Vižda ◽  
Y. Mazurová ◽  
F. Duška
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery ◽  
Left Coronary Artery ◽  
Background Activity ◽  
Experimental Myocardial Infarction ◽  
The Other ◽  
Tissue Samples ◽  
Ramus Interventricularis Anterior

SummaryExperimental infarctions were produced in 12 dogs by ligation of the Ramus interventricularis anterior of the left coronary artery, and their uptake of 99mTc-heparin was measured 7, 24 and 48 h as well as 7 days thereafter by recording an in vivo chest scintigram 4 h after intravenous injection of the compound. The dogs were subsequently killed, the heart removed and an in vitro scintigram obtained. Finally, the uptake of the compound was measured in tissue samples. The results indicate that 99mTc-heparin is accumulated in lesions which are not older than 24 h. At the other points in time uptake is low but even 24-h old lesions cannot be demonstrated reliably. The results are impaired by the high blood activity on the cardiac chambers and by the background activity of the lungs. In general, 99mTc-heparin has less useful properties than the more frequently employed 99mTc-pyrophosphate so that a change of procedure is not to be recommended.

Pyrophosphate Scan of the Temporarily Ischemized Dog Myocardium

1981 ◽  
Vol 20 (06) ◽  
pp. 268-271
Author(s):  
J. Novák ◽  
J. Vižďa ◽  
J. Kubíček ◽  
P. Kafka ◽  
O. Veverková ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Myocardial Ischemia ◽  
Histological Examination ◽  
Left Coronary Artery ◽  
Complete Occlusion ◽  
Transient Myocardial Ischemia ◽  
Ramus Interventricularis Anterior

In 9 dogs a transient myocardial ischemia was provoked using complete occlusion of the ramus interventricularis anterior of the left coronary artery. The occlusion was removed after 5, 10 or 15 min. Four hrs after removal of the occlusion a scan of the myocardium was carried out using 99mTc-labelled pyrophosphate. In 7 out of 9 dogs under study the scan was markedly positive, in 2 dogs negative. ECG demonstrated ischemic changes practically in all dogs; the changes became normal after removal of the occlusion, namely in 5 to 35 min. The histological examination of the tissue demonstrated in all 9 dogs only a slight impairment of the myocardium.

scholarly journals Diagnosis and Surgical Outcomes of Patients with Anomalous Left Coronary Artery from the Pulmonary Artery: A Single Taiwanese Medical Center Experience

2020 ◽  
Vol 23 (2) ◽  
pp. E101-E106
Author(s):  
Wan-Fu Hsu ◽  
Pi-Chang Lee ◽  
Hsing-Yuan Li ◽  
Shao-Wei Huang ◽  
Shyi-Jou Chen ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Pulmonary Artery ◽  
Surgical Outcomes ◽  
Left Coronary Artery ◽  
Surgical Intervention ◽  
Medical Center ◽  
Left Ventricular ◽  
Diagnostic Methods ◽  
Anomalous Left Coronary Artery ◽  
Anomalous Left Coronary

Background: Anomalous left coronary artery from the pulmonary artery (ALCAPA), a very rare congenital cardiac anomaly, is associated with a high mortality rate among infants who are not diagnosed or treated in a timely manner. Surgical intervention with the reconstruction for a two-coronary-system circulation is the main treatment; however, there have been very few reported cases from Taiwan. In this study, we aim to describe the clinical manifestations, diagnostic methods, surgery types, and surgical outcomes in patients with ALCAPA from a single Taiwanese medical center. Methods: We retrospectively reviewed patients diagnosed with ALCAPA who underwent surgery at our institution between January 2001 and October 2018. Clinical presentations, noninvasive and invasive study results, surgical methods, and postoperative follow-up results were assessed from medical records. Moreover, literature on this particular cardiovascular anomaly was reviewed. Results: The study included 6 patients (5 children and 1 adult). The diagnosis was confirmed using cardiac catheterization and coronary angiography in four patients and only echocardiography in two patients. All patients underwent surgical correction and survived. Four patients showed improvements in left ventricular function and mitral regurgitation (MR). Conclusion: Early diagnosis and timely surgical intervention could avoid mortality regardless of the method of operation. ALCAPA can be definitively diagnosed using noninvasive echocardiography. Both left ventricular systolic function and mitral insufficiency could improve after the surgical intervention in pediatric patients. Repair or replacement of the mitral valve could be reserved for persistent MR complicated with congestive heart failure, particularly in patients who received the initial operation beyond infancy.

scholarly journals Surgical intervention for anomalous origin of the left coronary artery from the pulmonary artery: The Tokyo experience

2001 ◽  
Vol 121 (4) ◽  
pp. 792-797 ◽  
Author(s):  
Yukihisa Isomatsu ◽  
Yasuharu Imai ◽  
Toshiharu Shin'oka ◽  
Mitsuru Aoki ◽  
Yusuke Iwata
Keyword(s):  
Coronary Artery ◽  
Pulmonary Artery ◽  
Left Coronary Artery ◽  
Surgical Intervention ◽  
Anomalous Origin

scholarly journals Surgical Intervention for Anomalous Origin of Left Coronary Artery From the Pulmonary Artery in Children: A Long-Term Follow-Up

2016 ◽  
Vol 101 (5) ◽  
pp. 1842-1848 ◽  
Author(s):  
Phillip S. Naimo ◽  
Tyson A. Fricke ◽  
Yves d’Udekem ◽  
Andrew D. Cochrane ◽  
Andrew Bullock ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Pulmonary Artery ◽  
Left Coronary Artery ◽  
Surgical Intervention ◽  
Anomalous Origin ◽  
Long Term Follow Up

scholarly journals Successful Surgical Treatment of a Giant Left Coronary Artery Aneurysm with Fistula

2021 ◽  
Vol 24 (5) ◽  
pp. E868-E869
Author(s):  
Huadong Li ◽  
Hong Yu ◽  
Yu Song ◽  
Lu Tong ◽  
Meng Zhao ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Surgical Treatment ◽  
Rare Case ◽  
Left Coronary Artery ◽  
Coronary Artery Aneurysm ◽  
Surgical Intervention ◽  
Artery Aneurysm ◽  
Fistula Formation ◽  
The Right ◽  
Low Prevalence

Coronary artery aneurysm (CAA) is an aortic catastrophe with low prevalence. Giant CAA is even more uncommon, requiring surgical intervention. Giant CAA usually originates from the proximal segments of the right coronary and the anterior descending arteries. Here we report a rare case of giant left CAA with fistula formation treated with successful surgery.

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