Effect of Dibenamine on LD100 following supralethal dose of total body gamma radiation

1961 ◽  
Vol 201 (2) ◽  
pp. 347-348
Author(s):  
Stanley W. Handford ◽  
Paul W. Johnson

Dibenamine, an adrenergic blocking agent, was administered to dogs immediately before they were subjected to a supralethal dose of whole body radiation. No significant differences in the course of acute radiation sickness or survival time (LD100) between the treated and sham-treated control groups were observed.

1961 ◽  
Vol 201 (2) ◽  
pp. 349-350
Author(s):  
Stanley W. Handford ◽  
Paul W. Johnson

To test the effect of hemorrhage on survival following wholebody exposure to a supralethal dose of radiation, three groups of dogs were bled 25% of their estimated blood volume. In group 1, bleeding was accomplished immediately before irradiation; in groups 2 and 3, 30 min and 48 hr, respectively, following irradiation. No significant alterations in the course of acute radiation sickness or survival time (LD100) were observed.


Author(s):  
A.V. Barabanova ◽  
A.J. Bushmanov ◽  
K.V. Kotenko

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