Estimation of whole-body capillary transport parameters from osmotic transient data

1982 ◽  
Vol 242 (3) ◽  
pp. R227-R236 ◽  
Author(s):  
M. B. Wolf
Keyword(s):  
Mathematical Model ◽  
Volume Regulation ◽  
Body Fluid ◽  
Fluid Volume ◽  
Whole Body ◽  
Transport Parameters ◽  
Mean Values ◽  
Body Fluid Volume ◽  
Fluid Volume Regulation ◽  
Cellular Water

A mathematical model has been developed of short-term, extrarenal, whole-body fluid volume regulation. The Kedem and Katchalsky equations are used to describe rapid movements of crystalloid and colloid solutes and water between five fluid compartments. Simulation results showing rapid cell volume changes following a hyperosmotic crystalloid infusion demonstrated the necessity of considering the effect of cellular water shifts in osmotic transient experiments. From measurements of plasma volume and osmolality in acutely nephrectomized dogs subjected to isosmotic and hyperosmotic NaCl infusions and with the model, six parameters related to capillary membrane transport of water and NaCl were estimated. The mean capillary filtration capacity from six experiments was estimated as 0.01 ml.min-1.mmHg-1.100 g-1 of dog. This increased about threefold due to the hyperosmolality. Mean values of capillary diffusion capacity and osmotic reflection coefficient for NaCl were 0.37 cm3.s-1.100 g-1 and 0.087, respectively. These results support the use of the osmotic transient approach and a mathematical model to study the role of microvascular transport in whole-body fluid volume regulation.

scholarly journals A Possible Physiological Role of Atrial Natriuretic Peptide in Body Fluid Volume Regulation

1988 ◽  
Vol 13 ◽  
pp. S62-S68
Author(s):  
Yasunobu Hirata ◽  
Masao Ishii ◽  
Kazushige Fukui ◽  
Hiroshi Hayakawa ◽  
Shin-ichiro Namba ◽  
...  
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Volume Regulation ◽  
Body Fluid ◽  
Physiological Role ◽  
Fluid Volume ◽  
Body Fluid Volume ◽  
Fluid Volume Regulation ◽  
Atrial Natriuretic

scholarly journals A Possible Physiological Role of Atrial Natriuretic Peptide in Body Fluid Volume Regulation

1989 ◽  
Vol 13 ◽  
pp. S62-S68 ◽  
Author(s):  
Yasunobu Hirata ◽  
Masao Ishii ◽  
Kazushige Fukui ◽  
Hiroshi Hayakawa ◽  
Shin-ichiro Namba ◽  
...  
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Volume Regulation ◽  
Body Fluid ◽  
Physiological Role ◽  
Fluid Volume ◽  
Body Fluid Volume ◽  
Fluid Volume Regulation ◽  
Atrial Natriuretic

Body fluid volume regulation in elasmobranch fish

2007 ◽  
Vol 148 (1) ◽  
pp. 3-13 ◽  
Author(s):  
W. Gary Anderson ◽  
Josi R. Taylor ◽  
Jonathan P. Good ◽  
Neil Hazon ◽  
Martin Grosell
Keyword(s):  
Volume Regulation ◽  
Body Fluid ◽  
Fluid Volume ◽  
Elasmobranch Fish ◽  
Body Fluid Volume ◽  
Fluid Volume Regulation

Segment-specific resistivity improves body fluid volume estimates from bioimpedance spectroscopy in hemodialysis patients

2006 ◽  
Vol 100 (2) ◽  
pp. 717-724 ◽  
Author(s):  
F. Zhu ◽  
M. K. Kuhlmann ◽  
G. A. Kaysen ◽  
S. Sarkar ◽  
C. Kaitwatcharachai ◽  
...  
Keyword(s):  
Gold Standard ◽  
Total Body Water ◽  
Body Fluid ◽  
Hemodialysis Patients ◽  
Fluid Volume ◽  
Whole Body ◽  
Bioimpedance Spectroscopy ◽  
Specific Resistivity ◽  
Body Fluid Volume ◽  
Total Body

Discrepancies in body fluid estimates between segmental bioimpedance spectroscopy (SBIS) and gold-standard methods may be due to the use of a uniform value of tissue resistivity to compute extracellular fluid volume (ECV) and intracellular fluid volume (ICV). Discrepancies may also arise from the exclusion of fluid volumes of hands, feet, neck, and head from measurements due to electrode positions. The aim of this study was to define the specific resistivity of various body segments and to use those values for computation of ECV and ICV along with a correction for unmeasured fluid volumes. Twenty-nine maintenance hemodialysis patients (16 men) underwent body composition analysis including whole body MRI, whole body potassium (40K) content, deuterium, and sodium bromide dilution, and segmental and wrist-to-ankle bioimpedance spectroscopy, all performed on the same day before a hemodialysis. Segment-specific resistivity was determined from segmental fat-free mass (FFM; by MRI), hydration status of FFM (by deuterium and sodium bromide), tissue resistance (by SBIS), and segment length. Segmental FFM was higher and extracellular hydration of FFM was lower in men compared with women. Segment-specific resistivity values for arm, trunk, and leg all differed from the uniform resistivity used in traditional SBIS algorithms. Estimates for whole body ECV, ICV, and total body water from SBIS using segmental instead of uniform resistivity values and after adjustment for unmeasured fluid volumes of the body did not differ significantly from gold-standard measures. The uniform tissue resistivity values used in traditional SBIS algorithms result in underestimation of ECV, ICV, and total body water. Use of segmental resistivity values combined with adjustment for body volumes that are neglected by traditional SBIS technique significantly improves estimations of body fluid volume in hemodialysis patients.

scholarly journals Fluid volume regulation in patients with heart failure

2021 ◽  
Vol 9 (5) ◽  
pp. 257-258
Author(s):  
Panagiota Anyfanti ◽  
Erasmia Sampani ◽  
Apostolos Tsapas
Keyword(s):  
Heart Failure ◽  
Volume Regulation ◽  
Fluid Volume ◽  
Patients With Heart Failure ◽  
Fluid Volume Regulation

scholarly journals Fluid volume regulation in patients with heart failure – Authors' reply

2021 ◽  
Vol 9 (5) ◽  
pp. 258
Author(s):  
Jesper Jensen ◽  
Massar Omar ◽  
Jacob Eifer Møller ◽  
Morten Schou
Keyword(s):  
Heart Failure ◽  
Volume Regulation ◽  
Fluid Volume ◽  
Patients With Heart Failure ◽  
Fluid Volume Regulation
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