scholarly journals Allergic Responses Induced by a Fungal BiopesticideMetarhizium anisopliaeand House Dust Mite Are Compared in a Mouse Model

2011 ◽  
Vol 2011 ◽  
pp. 1-13 ◽  
Author(s):  
Marsha D. W. Ward ◽  
Yong Joo Chung ◽  
Lisa B. Copeland ◽  
Donald L. Doerfler
Keyword(s):  
House Dust ◽  
House Dust Mite ◽  
Bronchoalveolar Lavage Fluid ◽  
Lavage Fluid ◽  
Specific Ige ◽  
Response Level ◽  
Similar Dose ◽  
Dust Mite ◽  
Ige Response ◽  
Serum Total Ige

Biopesticides can be effective in controlling their target pest. However, research regarding allergenicity and asthma development is limited. We compared the ability of fungal biopesticideMetarhizium anisopliae(MACA) and house dust mite (HDM) extracts to induce allergic responses in BALB/c mice. The extracts were administered by intratracheal aspiration at doubling doses (2.5–80 g protein) 4X over a four-week period. Three days after the last exposure, serum and bronchoalveolar lavage fluid (BALF) were collected. The extracts' relative allergenicity was evaluated based on response robustness (lowest significant dose response compared to control (0 g)). MACA induced a more robust serum total IgE response than HDM. However, in the antigen-specific IgE assay, a similar dose of both MACA and HDM was required to achieve the same response level. Our data suggest a threshold dose of MACA for allergy induction and thatM. anisopliaemay be similar to HDM in allergy induction potential.

Serum IgE Levels and Specific IgE Antibodies in House Dust Mite Allergy: Predictive Value

1983 ◽  
Vol 20 (2) ◽  
pp. 93-96 ◽  
Author(s):  
LF. Perrin ◽  
J. Sroussi ◽  
F Cea-Gil ◽  
P. Deviller ◽  
Y. Lasne
Keyword(s):  
House Dust ◽  
House Dust Mite ◽  
Predictive Value ◽  
Specific Ige ◽  
Ige Antibodies ◽  
Serum Ige ◽  
House Dust Mite Allergy ◽  
Mite Allergy ◽  
Dust Mite ◽  
Specific Ige Antibodies

scholarly journals House dust mite sensitisation and association with atopic dermatitis in Brunei

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Haziq Emran ◽  
Christina Siew Eng Chieng ◽  
Surita Taib ◽  
Anne Catherine Cunningham
Keyword(s):  
Atopic Dermatitis ◽  
House Dust ◽  
House Dust Mite ◽  
Retrospective Cohort ◽  
Specific Ige ◽  
Dermatophagoides Pteronyssinus ◽  
Food Allergens ◽  
Dust Mite ◽  
Storage Mite ◽  
Tropical Areas

AbstractIgE sensitisation in tropical areas is under-reported. A 2 year retrospective cohort study of allergy data specific to aero and food allergens in Brunei demonstrated that specific IgE levels to house dust mite (Dermatophagoides pteronyssinus, D.farinae, Blomia tropicalis) were highest in this population and correlated with atopic dermatitis (p < 0.001). Shrimp and peanut were the most common food allergens. A dominance of house/storage mite sensitization is seen in Brunei which is consistent with other tropical countries.

scholarly journals House dust-mite allergen exposure is associated with serum specific IgE but not with respiratory outcomes

Indoor Air ◽  
2014 ◽  
Vol 25 (3) ◽  
pp. 235-244 ◽  
Author(s):  
I. Bakolis ◽  
J. Heinrich ◽  
J. P. Zock ◽  
D. Norbäck ◽  
C. Svanes ◽  
...  
Keyword(s):  
House Dust ◽  
House Dust Mite ◽  
Specific Ige ◽  
Allergen Exposure ◽  
Mite Allergen ◽  
House Dust Mite Allergen ◽  
Dust Mite ◽  
Dust Mite Allergen ◽  
Respiratory Outcomes

The allergen-specific IgE reactivity pattern of Chinese house dust mite allergic patients

2007 ◽  
Vol &NA; ◽  
pp. S262
Author(s):  
Chunqing Zhang ◽  
Birgitte Gjesing ◽  
Henrik Ipsen ◽  
Helene Henmar ◽  
Michael Spangfort ◽  
...  
Keyword(s):  
House Dust ◽  
House Dust Mite ◽  
Specific Ige ◽  
Reactivity Pattern ◽  
Ige Reactivity ◽  
Dust Mite

Effect of acupuncture on house dust mite specific IgE, substance P, and symptoms in persistent allergic rhinitis

2016 ◽  
Vol 116 (6) ◽  
pp. 497-505 ◽  
Author(s):  
John Leslie McDonald ◽  
Peter K. Smith ◽  
Caroline A. Smith ◽  
Charlie Changli Xue ◽  
Brenda Golianu ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Substance P ◽  
House Dust ◽  
House Dust Mite ◽  
Specific Ige ◽  
Persistent Allergic Rhinitis ◽  
Dust Mite

scholarly journals Utility of Shrimp and Der p 10 specific IgE for Shrimp Allergy Diagnosis in Non-House Dust Mite Sensitized Patients

2017 ◽  
Author(s):  
Karen Thursday S. Tuano ◽  
Sara Anvari ◽  
Imelda Celine Hanson ◽  
Joud Hajjar ◽  
Filiz Seeborg ◽  
...  
Keyword(s):  
House Dust ◽  
House Dust Mite ◽  
Specific Ige ◽  
Cross Reactivity ◽  
Rank Test ◽  
Positive Skin Prick Test ◽  
Operating Characteristics ◽  
Positive Skin ◽  
Dust Mite ◽  
History Of

ABSTRACTBackgroundThere are no set specific IgE (sIgE) to predict shrimp allergy as cross-reactivity with other arthropods play a role in shrimp sensitization.ObjectiveThis study identifies the allergens associated with shrimp allergy in house dust mite (HDM) and non-HDM sensitized patients.MethodsPatients with shrimp sensitization (positive skin prick test [SPT] and/or sIgE) with/without history of clinical reaction were recruited. Allergy was confirmed by oral food challenge (OFC) except for patients with history of anaphylaxis. Shrimp allergic (SA) and shrimp tolerant (ST) patients were further classified based on HDM sensitivity. The sIgE to shrimp, shrimp and HDM components were performed. Fisher’s exact test, Wilcoxon sum rank test and receiver operating characteristics analyses were done.ResultsOf 79 patients recruited, 12 SA (7 positive OFC and 5 with history of anaphylaxis), 18 ST and 10 non-shrimp sensitized controls (NC) were enrolled. In non-HDM sensitized patients, sIgE to shrimp (10.5 kUA/L, p=0.012) and Der p 10 (4.09 kUA/L, p=0.035) were higher in SA patients. Shrimp sIgE ≥3.55 kUA/L had 100% sensitivity and 85.71% specificity (ROC=0.94[0.81, 1.0]). Der p 10 sIgE ≥3.98 kUA/L had sensitivity of 80% and specificity of 100% (ROC=0.86[0.57, 1.0]). rPen a 1 ≥1.1 kUA/L had sensitivity of 80% and specificity of 85.7% (ROC=0.80[0.47,1.0]).ConclusionsIn non-HDM sensitized patients, shrimp sIgE ≥3.55 kUA/L and Der p 10 sIgE≥3.98 kUA/L give 100% sensitivity and specificity, respectively, to diagnose shrimp allergy. HDM sensitivity can influence sIgE levels to shrimp and shrimp/HDM components due to cross-reactivity.

Sign in / Sign up

Export Citation Format

Share Document