scholarly journals An 11-Year-Old Child with Autosomal Dominant Polycystic Kidney Disease Who Presented with Nephrolithiasis

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Fatih Firinci ◽  
Alper Soylu ◽  
Belde Kasap Demir ◽  
Mehmet Turkmen ◽  
Salih Kavukcu
Keyword(s):  
Kidney Disease ◽  
General Population ◽  
Polycystic Kidney Disease ◽  
Autosomal Dominant ◽  
Renal Stones ◽  
Age Group ◽  
Metabolic Abnormalities ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney

Patients with autosomal dominant polycystic kidney disease become symptomatic and are diagnosed usually at adulthood. The rate of nephrolithiasis in these patients is 5–10 times the rate in the general population, and both anatomic and metabolic abnormalities play role in the formation of renal stones. However, nephrolithiasis is rare in childhood age group. In this paper, an 11-year-old child with autosomal dominant polycystic kidney disease presenting with nephrolithiasis is discussed.

scholarly journals Percutaneous Nephrolithotomy under Ultrasound Guidance in Patients with Renal Calculi and Autosomal Dominant Polycystic Kidney Disease: A Report of 11 Cases

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Xiao Wang ◽  
Xuecheng Yang ◽  
Xiulong Zhong ◽  
Zhenlin Wang ◽  
Senyao Xue ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Percutaneous Nephrolithotomy ◽  
Ultrasound Guidance ◽  
Autosomal Dominant ◽  
Renal Stones ◽  
Renal Calculi ◽  
Lateral Position ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney

Nephrolithiasis accelerates the renal failure in the patients with ADPKD. In order to evaluate the role of percutaneous nephrolithotomy in management of calculus in these patients, 11 patients with autosomal dominant polycystic kidney disease and renal stones were included in the study. Two patients had bilateral renal stones. All patients were treated by percutaneous nephrolithotomy under ultrasound guidance. 13 percutaneous nephrolithotomy procedures were performed in 1 stage by the urology team under ultrasound guidance. 5 people received second operation with flexible nephroscopy in lateral position. The success rate and morbidity and mortality of the technique and hospital stay were recorded.Results. The puncture procedure was fully successful in all cases. The renal function improved in these patients. 5 patients had moderate fever after the surgery. 5 patients received flexible nephroscopy to take out the residual calculi. 2 persons had ESWL therapy after the surgery.Conclusion. PCNL is an ideal, safe, and effective method to remove the stones from those patients with no definite increase in the risk of complication. The outcome and stone-free rate are satisfactory comparable to the PCNL in the patients without ADPKD.

scholarly journals Association between Nephrolithiasis, Hypertension and Obesity in Polycystic Kidney Disease

2015 ◽  
Vol 4 (1) ◽  
pp. 43-46 ◽  
Author(s):  
Valbona Bajrami ◽  
Alma Idrizi ◽  
Enver Roshi ◽  
Myftar Barbullushi
Keyword(s):  
Blood Pressure ◽  
Kidney Disease ◽  
Diastolic Blood Pressure ◽  
Polycystic Kidney Disease ◽  
Autosomal Dominant ◽  
Total Cholesterol Level ◽  
Renal Stones ◽  
Polycystic Kidney ◽  
Metabolic Evaluation ◽  
Autosomal Dominant Polycystic Kidney

AIM: We aim to define the correlations between nephrolithiasis, hypertension, age and obesity in patients with autosomal dominant polycystic kidney disease (ADPKD) in Albania. MATERIAL AND METHODS: We included 100 patients with autosomal dominant polycystic kidney from 2011 to 2014. The patients underwent X-ray and renal ultrasonography. We performed the metabolic evaluation of blood and urine.RESULTS: The patients with renal stones had a higher level of mean systolic and diastolic blood pressure compared with patients without stones (155 ± 12 mmHg vs. 145 ± 8 mmHg, and 105 ± 0.9 mmHg vs. 92 ± 1.28 mmHg, respectively). Patients with renal stones were older (47 ± 15 vs. 38 ± 5 years), had a higher prevalence of obesity [body mass index (BMI): 28 ± 2.4 vs. 25.7 ± 0.6], had higher levels of total cholesterol level (220 ± 5 mg/dl vs. 203 ± 4 mg/dl) as well as triglyceride levels (160 ± 9 mg/dl vs. 126 ± 4 mg/dl), compared with no renal stone individuals. CONCLUSION: ADPKD patients with renal stones in our study had a higher mean level of systolic and diastolic blood pressure, BMI and cholesterol and triglycerides levels compared with individuals without renal stones.

scholarly journals Renal cell carcinoma in autosomal dominant polycystic kidney disease.

1994 ◽  
Vol 4 (9) ◽  
pp. 1661-1669 ◽  
Author(s):  
D S Keith ◽  
V E Torres ◽  
B F King ◽  
H Zincki ◽  
G M Farrow
Keyword(s):  
Renal Cell Carcinoma ◽  
Kidney Disease ◽  
General Population ◽  
Cell Carcinoma ◽  
Polycystic Kidney Disease ◽  
Renal Cell ◽  
Autosomal Dominant ◽  
White Blood Cells ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney

To provide information on the clinical presentation, diagnosis, pathology, and biologic behavior of renal cell carcinoma in patients with autosomal dominant polycystic kidney disease (ADPKD), three cases seen at this institution between 1955 and 1992, as well as the cases reported in the literature, were reviewed in detail. No male predominance was observed (12 men, 13 women) in the 25 patients who met the inclusion criteria. The age of presentation was earlier than that seen in the general population (45 versus 61 yr). Fever, night sweats, and weight loss were prominent at presentation. Fever is a more common presenting symptom of renal cell carcinoma in ADPKD (32%) than in the general population (7%). Twenty percent of the patients had metastatic disease at presentation. Even with computed tomography and magnetic resonance, the diagnosis was difficult and often delayed, and the accumulation of 111In-labeled white blood cells can wrongly suggest a cyst infection. Renal cell carcinoma in ADPKD is more often concurrently bilateral (12 versus 1 to 5%), multicentric (28 versus 6%), and sarcomatoid in type (33 versus 1 to 5%) than in the general population. Because previous studies have failed to demonstrate a higher prevalence of renal cell carcinoma in ADPKD, this information suggests either a malignant potential restricted to a small subset of patients with this disease or an alteration in the biologic behavior of renal cell carcinoma when it develops in the setting of ADPKD.

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