Biliary Adenofibroma with Carcinoma In Situ: A Rare Case Report
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This case report exhibits a rare biliary tumor within the liver of a 53-year-old Caucasian woman. This exophytic, multicystic, 6.5×5.0 cm mass was composed of complex tubulocystic structures lined by nonmucin-secreting, biliary epithelium embedded in fibrous stroma, consistent with biliary adenofibroma. This is the seventh case described in the literature. Multiple foci of high-grade dysplasia/carcinoma in situ were found with a microscopic focus of invasive carcinoma in review of the pathology, making this only the second case reporting malignant transformation. It is presented to illustrate the premalignant potential in a biliary epithelial tumor currently categorized as benign.
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2018 ◽
Vol 126
(3)
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pp. e72-e73
1968 ◽
Vol 21
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pp. 173-180
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2019 ◽
Vol 215
(11)
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pp. 152624
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2015 ◽
Vol 23
(3)
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pp. 722-728
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