scholarly journals Cytological Features of Mammary Analogue Secretory Carcinoma of the Parotid Gland in a 15-Year-Old Girl: A Case Report with Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Takako Inaba ◽  
Yuki Fukumura ◽  
Tsuyoshi Saito ◽  
Junkichi Yokoyama ◽  
Shinichi Ohba ◽  
...  

Mammary analogue secretory carcinoma (MASC) is a recently recognized tumor of salivary glands characterized by the ETV6-NTRK3 fusion gene. This tumor is very rare in children and adolescents. We report a case of MASC in a 15-year-old girl, the fifth youngest case so far reported. The patient complained of a left infra-auricular mass that gradually enlarged for a year. Fine-needle aspiration cytology/imprint cytology showed individual tumor cells that had faintly eosinophilic granular cytoplasm with secretion granules sometimes seen adjacent to the tumor cells. These cytological features overlapped between those of zymogen granule-poor acinic cell carcinoma (AciCC) and MASC. In addition to the case report, we present a review of the related literature with a focus on the cytological features of MASC. The differential diagnostic clues are also discussed.

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Neeta Kumar ◽  
Shahin Sayed ◽  
Sudhir Vinayak

A case of multifocal Langerhans cell histiocytosis in a two-year-old child is presented where fine needle aspiration was helpful in achieving a rapid and accurate diagnosis in an appropriate clinical and radiological setting. This can avoid unnecessary biopsy and guide the management especially where access to histopathology is limited. The highly characteristic common and rare cytological features are highlighted with focus on differential diagnoses and causes of pitfalls.


2014 ◽  
Vol 42 (10) ◽  
pp. 846-855 ◽  
Author(s):  
Kayoko Higuchi ◽  
Makoto Urano ◽  
Reisuke H. Takahashi ◽  
Hisashi Oshiro ◽  
Jun Matsubayashi ◽  
...  

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