scholarly journals Diagnosis and Management of Cirrhosis-Related Osteoporosis

2016 ◽  
Vol 2016 ◽  
pp. 1-12 ◽  
Author(s):  
Lívia Alves Amaral Santos ◽  
Fernando Gomes Romeiro
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Liver Transplantation ◽  
Primary Biliary Cirrhosis ◽  
Biliary Cirrhosis ◽  
Immunosuppressant Therapy ◽  
Treatment Of Osteoporosis ◽  
Screening Strategies ◽  
Cirrhotic Patients

Management of cirrhosis complications has greatly improved, increasing survival and quality of life of the patients. Despite that, some of these complications are still overlooked and scarcely treated, particularly those that are not related to the liver. This is the case of osteoporosis, the only cirrhosis complication that is not solved after liver transplantation, because bone loss often increases after immunosuppressant therapy. In this review, the definitions of bone conditions in cirrhotic patients are analyzed, focusing on the more common ones and on those that have the largest impact on this population. Risk factors, physiopathology, diagnosis, screening strategies, and treatment of osteoporosis in cirrhotic patients are discussed, presenting the more striking data on this issue. Therapies used for particular conditions, such as primary biliary cirrhosis and liver transplantation, are also presented.

S1782 Health Related Quality of Life in Patients with Primary Biliary Cirrhosis Using a Japanese Version of the PBC-40 Questionnaire

2008 ◽  
Vol 134 (4) ◽  
pp. A-268
Author(s):  
Satoru Kakizaki ◽  
Shintarou Shiba ◽  
Ken Sato ◽  
Naondo Sohara ◽  
Daichi Takizawa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Primary Biliary Cirrhosis ◽  
Japanese Version ◽  
Biliary Cirrhosis ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals PSYCHOMETRIC PROPERTY OF FATIGUE SEVERITY SCALE AND CORRELATION WITH DEPRESSION AND QUALITY OF LIFE IN CIRRHOTICS

2017 ◽  
Vol 54 (4) ◽  
pp. 344-348 ◽  
Author(s):  
Danusa ROSSI ◽  
Lucas Homercher GALANT ◽  
Claudio Augusto MARRONI
Keyword(s):  
Quality Of Life ◽  
Liver Transplantation ◽  
Construct Validity ◽  
Discriminant Validity ◽  
Depressive Symptomatology ◽  
Severity Scale ◽  
Fatigue Severity ◽  
Cirrhotic Patients ◽  
The Mean

ABSTRACT BACKGROUND: Fatigue is a common complaint in cirrhotic patients and may be considered a debilitating symptom with negative impact on quality of life. Research on its etiology and treatment has been hampered by the lack of relevant and reproducible measures of fatigue. OBJECTIVE: To evaluate the psychometric properties of the Fatigue Severity Scale (FSS) in cirrhotic patients and to correlate with depressive symptomatology and quality of life. METHODS: Cross-sectional study with a convenience sample of 106 cirrhotic patients, aged between 18 and 70 years, both genders, literate, pre and post liver transplantation in outpatient follow-up. Internal consistency, reproducibility, discriminant validity, criterion validity, construct validity, responsiveness criterion, depressive symptomatology and quality of life were evaluated through questionnaires between January and October 2015. RESULTS: The mean age was 54.75±9.9 years, 65.1% male and 32.1% of the sample had cirrhosis due to hepatitis C virus. The mean FSS score was 4.74±1.64. Cronbach’s alpha was 0.93, and the Intraclass Correlation Coefficient was 0.905 (95% CI: 0.813-0.952). For discriminant validity, FSS differentiated scores from different groups (P=0.009) and presented a correlation with the Modified Fatigue Impact Scale (r=0.606, P=0.002). FSS correlated significantly and positively with depressive symptomatology and correlated negatively with the SF-36 domains for construct validity. For responsiveness, no significant changes were observed in the fatigue scores in the pre and post-liver transplantation periods (P=0.327). CONCLUSION: FSS showed good psychometric performance in the evaluation of fatigue in patients with cirrhosis. Fatigue presented a strong correlation with depressive symptomatology and quality of life.

Quality of life and illness perception in primary biliary cirrhosis: A controlled cross-sectional study

2015 ◽  
Vol 39 (1) ◽  
pp. 52-58 ◽  
Author(s):  
Aurélie Untas ◽  
Emilie Boujut ◽  
Christophe Corpechot ◽  
Franck Zenasni ◽  
Olivier Chazouillères ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Primary Biliary Cirrhosis ◽  
Illness Perception ◽  
Cross Sectional Study ◽  
Biliary Cirrhosis ◽  
Sectional Study ◽  
Cross Sectional
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