scholarly journals Twelve-Year Follow-Up of Laser In Situ Keratomileusis for Moderate to High Myopia

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Tetsuya Ikeda ◽  
Kimiya Shimizu ◽  
Akihito Igarashi ◽  
Sumie Kasahara ◽  
Kazutaka Kamiya
Keyword(s):  
High Myopia ◽  
Central Corneal Thickness ◽  
Pearson Correlation ◽  
Corneal Thickness ◽  
Laser In Situ Keratomileusis ◽  
Manifest Refraction ◽  
Observation Period

Purpose. To assess the long-term clinical outcomes of conventional laser in situ keratomileusis (LASIK) for moderate to high myopia.Methods. We retrospectively examined sixty-eight eyes of 37 consecutive patients who underwent conventional LASIK for the correction of myopia (−3.00 to −12.75 diopters (D)). At 3 months and 1, 4, 8, and 12 years postoperatively, we assessed the safety, efficacy, predictability, stability, mean keratometry, central corneal thickness, and adverse events.Results. The safety and efficacy indices were0.82±0.29and0.67±0.37, respectively, 12 years postoperatively. At 12 years, 53% and 75% of the eyes were within 0.5 and 1.0 D, respectively, of the targeted correction. Manifest refraction changes of −0.74±0.99 D occurred from 3 months to 12 years after LASIK (p<0.001). We found a significant correlation of refractive regression with the changes in keratometric readings from 3 months to 12 years postoperatively (Pearson correlation coefficient,r=-0.28,p=0.02), but not with the changes in central corneal thickness (r=-0.08,p=0.63). No vision-threatening complications occurred in any case.Conclusions. Conventional LASIK offered good safety outcomes during the 12-year observation period. However, the efficacy and the predictability gradually decreased with time owing to myopic regression in relation to corneal steepening.

Femtosecond-assisted laser in situ keratomileusis for high myopia correction: Long-term follow-up outcomes.

2019 ◽  
Vol 30 (3) ◽  
pp. 446-454 ◽  
Author(s):  
Alfredo Vega-Estrada ◽  
Jorge L Alio
Keyword(s):  
Excimer Laser ◽  
Repetition Rate ◽  
High Myopia ◽  
Spherical Aberration ◽  
Pearson Correlation ◽  
Laser In Situ Keratomileusis ◽  
Long Term Follow Up

Objective: Report the outcomes of laser in situ keratomileusis (LASIK) for high myopia correction after long-term follow-up. Methods: Retrospective, consecutive, clinical study including 70 eyes that underwent LASIK using a 500 Hertz (Hz) repetition rate excimer laser and femtosecond technology for flap creation. Visual, refractive, corneal aberrations, and correlation among the variables were evaluated during 3 years. In addition, 34 eyes were followed during 5 years. Results: Significant improvement of 17 logMAR lines was observed in uncorrected vision at 5 years (p < 0.01). This was consistent with spherical equivalent reduction that came from mean preoperative –7.79 diopters (D) to 5 years postoperative –0.24 D (p < 0.01). Significant induction of primary spherical aberration and coma aberration was also found (p < 0.01) at 3 months with levels of 0.61 µm and 0.47 µm, respectively, with no further changes at 5 years (p > 0.05). Pearson correlation showed that the amount of high-order aberrations at 3 months postoperativeley was significantly correlated with the changes in the keratometry throughout the 5 years (delta K) (R2 0.242 p = 0.05). Finally, preoperative corneal asphericity showed an inverse correlation with the delta K (R2 –308 p = 0.01). Conclusions: Results from this study suggests that LASIK for high myopia correction using 500 Hz repetition rate excimer laser provides stable visual, refractive and aberrometric results after 5 years of follow-up. A more prolate cornea and the amount of higher-order aberrations induced after LASIK are factors that negatively impact in the long-term stability of the procedure.

scholarly journals Long-term evaluation of eyes with central corneal thickness <400 µm following laser in situ keratomileusis

2016 ◽  
pp. 535 ◽  
Author(s):  
Mohammad Reza Djodeyre ◽  
Jaime Beltran ◽  
Julio Ortega-Usobiaga ◽  
Felix Gonzalez-Lopez ◽  
Ana Ruiz-Rizaldos ◽  
...  
Keyword(s):  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Laser In Situ Keratomileusis ◽  
Term Evaluation

scholarly journals Laser-Assisted Subepithelial Keratectomy versus Laser In Situ Keratomileusis in Myopia: A Systematic Review and Meta-Analysis

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Li-Quan Zhao ◽  
Huang Zhu ◽  
Liang-Mao Li
Keyword(s):  
Systematic Review ◽  
Visual Acuity ◽  
High Myopia ◽  
Meta Analysis ◽  
Laser In Situ Keratomileusis ◽  
Corneal Haze ◽  
Refractive Outcomes ◽  
Manifest Refraction

This systematic review was to compare the clinical outcomes between laser-assisted subepithelial keratectomy (LASEK) and laser in situ keratomileusis (LASIK) for myopia. Primary parameters included mean manifest refraction spherical equivalent (MRSE), MRSE within ±0.50 diopters, uncorrected visual acuity (UCVA) ≥20/20, and loss of ≥1 line of best-corrected visual acuity (BCVA). Secondary parameters included flap complications and corneal haze. Twelve clinical controlled trials were identified and used for comparing LASEK (780 eyes) to LASIK (915 eyes). There were no significant differences in visual and refractive outcomes between the two surgeries for low to moderate myopia. The incidence of loss of ≥1 line of BCVA was significantly higher in moderate to high myopia treated by LASEK than LASIK in the mid-term and long-term followup. The efficacy (MRSE and UCVA) of LASEK appeared to be a significant worsening trend in the long-term followup. Corneal haze was more severe in moderate to high myopia treated by LASEK than LASIK in the mid-term and long-term followup. The flap-related complications still occurred in LASIK, but the incidence was not significantly higher than that in LASEK. LASEK and LASIK were safe and effective for low to moderate myopia. The advantage of LASEK was the absence of flap-related complications, and such procedure complication may occur in LASIK and affect the visual results. The increased incidence of stromal haze and regression in LASEK significantly affected the visual and refractive results for high myopia.

Correlation of intraocular pressure and central corneal thickness in normal myopic eyes and after laser in situ keratomileusis

1998 ◽  
Vol 24 (10) ◽  
pp. 1320-1325 ◽  
Author(s):  
Barry Emara ◽  
Louis E. Probst ◽  
David P. Tingey ◽  
Dennis W. Kennedy ◽  
Lisa J. Willms ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Laser In Situ Keratomileusis

scholarly journals Predictors affecting myopic regression in − 6.0D to − 10.0D myopia after laser-assisted subepithelial keratomileusis and laser in situ keratomileusis flap creation with femtosecond laser-assisted or mechanical microkeratome-assisted

2019 ◽  
Vol 40 (1) ◽  
pp. 213-225 ◽  
Author(s):  
Jihong Zhou ◽  
Wei Gu ◽  
Shaowei Li ◽  
Lijuan Wu ◽  
Yan Gao ◽  
...  
Keyword(s):  
Femtosecond Laser ◽  
Contact Lens ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Case Series ◽  
Older Age ◽  
Laser In Situ Keratomileusis ◽  
Corneal Curvature ◽  
Case Series Study

Abstract Purpose To investigate the predictive factors of postoperative myopic regression among subjects who have undergone laser-assisted subepithelial keratomileusis (LASEK), laser-assisted in situ keratomileusis (LASIK) flap created with a mechanical microkeratome (MM), and LASIK flap created with a femtosecond laser (FS). All recruited patients had a manifest spherical equivalence (SE) from − 6.0D to − 10.0D myopia. Methods This retrospective, observational case series study analyzed outcomes of refraction at 1 day, 1 week, and 1, 3, 6, and 12 months postoperatively. Predictors affecting myopic regression and other covariates were estimated with the Cox proportional hazards model for the three types of surgeries. Results The study enrolled 496 eyes in the LASEK group, 1054 eyes in the FS-LASIK group, and 910 eyes in the MM-LASIK group. At 12 months, from − 6.0D to − 10.0D myopia showed that the survival rates (no myopic regression) were 52.19%, 59.12%, and 58.79% in the MM-LASIK, FS-LASIK, and LASEK groups, respectively. Risk factors for myopic regression included thicker postoperative central corneal thickness (P ≦ 0.01), older age (P ≦ 0.01), aspherical ablation (P = 0.02), and larger transitional zone (TZ) (P = 0.03). Steeper corneal curvature (Kmax) (P = 0.01), thicker preoperative central corneal thickness (P < 0.01), smaller preoperative myopia (P < 0.01), longer duration of myopia (P = 0.02), with contact lens (P < 0.01), and larger optical zone (OZ) (P = 0.02) were protective factors. Among the three groups, the MM-LASIK had the highest risk of postoperative myopic regression (P < 0.01). Conclusions The MM-LASIK group experienced the highest myopic regression, followed by the FS-LASIK and LASEK groups. Older age, aspheric ablation used, thicker postoperative central corneal thickness, and enlarging TZ contribute to myopic regression; steeper preoperative corneal curvature (Kmax), longer duration of myopia, with contact lens, thicker preoperative central corneal thickness, lower manifest refraction SE, and enlarging OZ prevent postoperative myopic regression in myopia from − 6.0D to − 10.0D.

Changes in Central Corneal Thickness After Laser in situ Keratomileusis and Photorefractive Keratectomy

2003 ◽  
Vol 19 (2) ◽  
pp. 149-153
Author(s):  
Igor Kozak ◽  
Marek Hornak ◽  
Tomas Juhas ◽  
Arvind Shah ◽  
E Franklin Rawlings
Keyword(s):  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Laser In Situ Keratomileusis ◽  
Photorefractive Keratectomy

Comparison of laser in situ keratomileusis and photorefractive keratectomy results: Long-term follow-up

2008 ◽  
Vol 34 (9) ◽  
pp. 1527-1531 ◽  
Author(s):  
Takashi Miyai ◽  
Kazunori Miyata ◽  
Ryohei Nejima ◽  
Masato Honbo ◽  
Keiichiro Minami ◽  
...  
Keyword(s):  
Laser In Situ Keratomileusis ◽  
Photorefractive Keratectomy ◽  
Long Term Follow Up
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