scholarly journals Cheilitis Glandularis of Both Lips: Successful Treatment with a Combination of an Intralesional Steroid Injection and Tacrolimus Ointment

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Norberto Sugaya ◽  
Dante Migliari
Keyword(s):  
Salivary Glands ◽  
Successful Treatment ◽  
Clinical Presentation ◽  
Steroid Injection ◽  
Inflammatory Condition ◽  
Minor Salivary Glands ◽  
Successful Management ◽  
Tacrolimus Ointment ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection

Cheilitis glandularis (CG) is an inflammatory condition of unknown cause that predominantly affects the minor salivary glands of the lips. Although a diagnosis of CG is not difficult, its treatment is a challenge. This article highlights the clinical presentation of the disease together with a case of successful management of this disease using a combination of a steroid injection followed by a topical immunosuppressor.

The Efficacy of Skin Cooling for Pain Relief during Intralesional Steroid Injection for Keloid Treatment: A Randomized Cross-Over Study

2021 ◽  
Vol 104 (11) ◽  
pp. 1752-1757
Keyword(s):  
Treatment Group ◽  
Rating Scale ◽  
Steroid Injection ◽  
Pairwise Comparison ◽  
Random Order ◽  
Repeated Measure ◽  
Skin Cooling ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection ◽  
Pre Treatment

Objective: To evaluate if pre-treatment skin cooling can reduce the pain during steroid injection. Materials and Methods: A randomized cross-over study was conducted between September 2015 and October 2016. This study received ethical approval ID035904 No. MURA2016/152. Forty-four subjects with keloid that needed intralesional steroid injection were divided into three pretreatment groups, no treatment, skin cooling with ice pack, and skin applying with a mixture of lidocaine 2.5% and prilocaine 2.5% (EMLA®), in random order. Pain intensity was measured by using 100-mm visual analogue scale (VAS). The satisfaction levels were assessed with orderly interval rating scale from 1 to 5. Repeated-measure analysis of variance (ANOVA) and Bonferroni pairwise comparison were used for data analyses. Results: The mean VAS score at the time of needle puncturing into the skin and during steroid infiltration was statistically significant lower in skin cooling compared to no treatment group (p<0.001) and EMLA group (p<0.05). The satisfaction level was also statistically significant higher in skin cooling compared to no treatment group (p<0.001) and EMLA group (p<0.001). Thirty-seven patients (84%) selected skin cooling method as the most favorable pre-anesthetic method for intralesional steroid injection. Conclusion: Skin cooling with ice before intralesional steroid injection of keloid effectively reduces pain and patients are also satisfied. Keyword: Keloid, Corticosteroid, Pre-treatment, pain, skin cooling

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