scholarly journals Finite-Time Robust Stability of Uncertain Genetic Regulatory Networks with Time-Varying Delays and Reaction-Diffusion Terms

Complexity ◽  
2019 ◽  
Vol 2019 ◽  
pp. 1-18 ◽  
Author(s):  
Wenqin Wang ◽  
Yali Dong ◽  
Shouming Zhong ◽  
Feng Liu

This study seeks to address the finite-time robust stability of delayed genetic regulatory networks (GRNs) with uncertain parameters and reaction-diffusion terms. We employ an appropriate Lyapunov-Krasovskii functional to derive some less conservative stability criteria for GRNs under Dirichlet boundary conditions, which are delay-dependent, delay-derivative-dependent, and reaction-diffusion-dependent. The time-varying delays and their derivatives are both bounded with lower and upper bounds, where the lower bound of them can be zero or non-zero. In addition, we define some new variables to deal with uncertain parameters. Moreover, Jensen’s integral inequality, Wirtinger-type integral inequality, reciprocally convex combination inequality, Gronwall inequality, and Green formula are employed to handle integral terms. Finally, a numerical example is presented to illustrate the feasibility and effectiveness of the obtained stability criteria.

Complexity ◽  
2018 ◽  
Vol 2018 ◽  
pp. 1-15 ◽  
Author(s):  
Xiaofei Fan ◽  
Yantao Wang ◽  
Ligang Wu ◽  
Xian Zhang

It will be settled out for the open problem of designing an r-order finite-time (F-T) state observer for reaction-diffusion genetic regulatory networks (RDGRNs) with time-varying delays. By assuming the Dirichlet boundary conditions, aiming to estimate the mRNA and protein concentrations via available network measurements. Firstly, sufficient F-T stability conditions for the filtering error system have been investigated via constructing an appropriate Lyapunov–Krasovskii functional (LKF) and using several integral inequalities and (reciprocally) convex technique simultaneously. These conditions are delay-dependent and reaction-diffusion-dependent and can be checked by MATLAB toolbox. Furthermore, a method is proposed to design an r-order F-T state observer, and the explicit expressions of observer gains are given. Finally, a numerical example is presented to illustrate the effectiveness of the proposed method.


Author(s):  
Xiongbo Wan ◽  
◽  
Chuanyu Ren ◽  
Jianqi An

This study investigates stability problems related to discrete-time randomly switched genetic regulatory networks (GRNs) with time-varying delays. A new discrete-time randomly switched GRN model with known sojourn probabilities is proposed. By utilizing the discrete Wirtinger-based inequality and a newly proposed constraint condition on the feedback regulatory function, which have not been fully used in stability analysis of discrete-time GRNs, we establish delay-dependent stability and robust stability criteria. These criteria possess the sojourn probabilities of randomly switched GRNs. Two numerical examples are provided to demonstrate the effectiveness of the established results.


Complexity ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-21
Author(s):  
Shanmugam Saravanan ◽  
M. Syed Ali ◽  
Grienggrai Rajchakit ◽  
Bussakorn Hammachukiattikul ◽  
Bandana Priya ◽  
...  

The problem of finite-time stability of switched genetic regulatory networks (GRNs) with time-varying delays via Wirtinger’s integral inequality is addressed in this study. A novel Lyapunov–Krasovskii functional is proposed to capture the dynamical characteristic of GRNs. Using Wirtinger’s integral inequality, reciprocally convex combination technique and the average dwell time method conditions in the form of linear matrix inequalities (LMIs) are established for finite-time stability of switched GRNs. The applicability of the developed finite-time stability conditions is validated by numerical results.


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