scholarly journals “Recurrent Papillary Necrosis and Nephrocalcinosis Induced by Nonsteroidal Anti-Inflammatory Drugs for Gouty Arthritis Associated with Congenital Chloride-Losing Diarrhea: A Major Risk for Kidney Loss”

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Kamel El-Reshaid ◽  
Shaikha Al-Bader ◽  
Hossameldin Sallam
Keyword(s):  
Renal Failure ◽  
Genetic Disorder ◽  
Gouty Arthritis ◽  
Watery Diarrhea ◽  
Recessive Mutation ◽  
Papillary Necrosis ◽  
Autosomal Recessive Mutation ◽  
Inflammatory Drugs ◽  
Long Term Prognosis

Congenital chloride-losing diarrhea (CCLD) is a rare genetic disorder due to autosomal recessive mutation in the SLC26A3 gene on chromosome 7. It is characterized with chronic watery diarrhea with high fecal chloride (Cl: >90 mmol/L), low potassium (K), and metabolic alkalosis with low urinary Cl and K. The overall long-term prognosis is favorable with optimal life-long salt and K supplementation. In this case report, we describe a man with progressive renal failure and small kidneys that showed nephrocalcinosis and papillary necrosis. His disease was diagnosed since birth and was confirmed by our tests. He was incompliant with therapy and had developed gout. The latter complication of his disease has led to excessive NSAID use over the past years. Reinstitution of diet, drug therapy, and allopurinol had stabilized his renal disease for 1 year of follow-up. In conclusion, excessive analgesic use is a risk factor for renal failure in CCLD.

The Long-Term Prognosis of AA and AL Renal Amyloidosis and the Pathogenesis of Chronic Renal Failure in Renal Amyloidosis*

1993 ◽  
Vol 189 (3) ◽  
pp. 316-331 ◽  
Author(s):  
A. Bohle ◽  
M. Wehrmann ◽  
R. Eissele ◽  
H.v. Gise ◽  
S. Mackensen-Haen ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Amyloidosis ◽  
Long Term Prognosis

Long-Term Prognosis of Acute Renal Failure in the Full-Term Neonate

1998 ◽  
Vol 37 (6) ◽  
pp. 381-385 ◽  
Author(s):  
Cesare Polito ◽  
Maria Rosaria Papale ◽  
Angela La Manna
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Full Term ◽  
Term Neonate ◽  
Long Term Prognosis

scholarly journals Postpartum atypical haemolytic uremic syndrome: a rare case report

2020 ◽  
Vol 9 (11) ◽  
pp. 4710
Author(s):  
Neha Khatod ◽  
Shubhra Mukharjee ◽  
Vijay Malviya
Keyword(s):  
Renal Failure ◽  
Rare Case ◽  
Blood Transfusions ◽  
Haemolytic Uremic Syndrome ◽  
Aggressive Management ◽  
Rare Case Report ◽  
Uremic Syndrome ◽  
Long Term Prognosis ◽  
In Pregnancy

Hemolytic uremic syndrome (HUS) is characterized by triad of microangiopathic hemolytic anaemia, Thrombocytopenia and Acute renal failure. Genetically predisposed women develop HUS and may be triggered by pregnancy. The diagnosis is challenging due to overlapping clinical features of other diseases in pregnancy. The long-term prognosis is guarded. We are presenting a case of a young primigravida who underwent emergency lower (uterine) segment caesarean section (LSCS). She developed progressive anaemia, thrombocytopenia and renal failure postoperatively. Aggressive management with plasmapheresis, blood transfusions and hemodialysis saved her life. She is currently in remission.

Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome – A Pictorial Review

2019 ◽  
Vol 1 ◽  
pp. 41-46
Author(s):  
Moomal Haris ◽  
Harun Gupta
Keyword(s):  
Inflammatory Process ◽  
Clinical Presentation ◽  
Symptom Control ◽  
Clinical Syndrome ◽  
First Line ◽  
Pictorial Review ◽  
Inflammatory Arthropathy ◽  
Inflammatory Drugs ◽  
Long Term Prognosis

Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) is an acronym which encompasses SAPHO. SAPHO is a distinct clinical syndrome which involves the musculoskeletal and dermatological systems. The clinical presentation can be variable, and therefore, patients may present to non-specialists who are not familiar with the disease. It is, therefore, important for the radiologist to be aware of the imaging manifestations of SAPHO; as often, it is them who are the first to propose the diagnosis. Imaging allows differentiation of SAPHO from other disease processes such as inflammatory arthropathy, infection, and malignancy which can share similar features and also to demonstrate potentially subclinical areas of disease involvement. Treatment is empirical and aimed at symptom control and modifying the inflammatory process. Nonsteroidal anti-inflammatory drugs are the first-line agents. The disease has a good long-term prognosis, despite the challenges in diagnosis and treatment.

scholarly journals MP215ACUTE RENAL FAILURE SECONDARY TO RENINE ANGIOTENSIN SYSTEM BLOKERS SHORT AND LONG TERM PROGNOSIS

2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii506-iii506
Author(s):  
Najla Dammak ◽  
Khawla Kammoun ◽  
Salma Toumi ◽  
Yosr Chaabouni ◽  
Mahmoud Kharrat ◽  
...  
Keyword(s):  
Renal Failure ◽  
Angiotensin System ◽  
Short And Long Term ◽  
Long Term Prognosis

scholarly journals ATYPICAL HEMOLYTIC-UREMIC SYNDROME DURING PREGNANCY. PRESENT AND LATEST RESULTS OF TREATMENT

2019 ◽  
Vol 6 (1) ◽  
pp. 47-50
Author(s):  
N. A Zharkin ◽  
M. E Statsenko ◽  
M. M Stazharova ◽  
Natalia A. Burova ◽  
S. A Prokhvatilov
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Hemolytic Uremic Syndrome ◽  
Clinical Case ◽  
Atypical Hemolytic Uremic Syndrome ◽  
Results Of Treatment ◽  
Pathogenetic Therapy ◽  
Uremic Syndrome ◽  
Long Term Prognosis

Atypical hemolytic-uremic syndrome being referred to autoimmune diseases appears to be one of the most severe forms of thrombosis and microangiopathy. Difficulties in diagnosis cause a delay in pathogenetic therapy, which causes a high maternal mortality rate. Pathogenetic therapy with eculizumab, suppressing the terminal activity of complement, may contribute to the recovery of blood coagulation properties, but the long-term prognosis for chronic renal failure remains unfavorable. The article deals with a clinical case confirming this conclusion.

Reversible Renal Failure Associated with Ibuprofen: Case Report and Review of the Literature

1984 ◽  
Vol 18 (1) ◽  
pp. 27-33 ◽  
Author(s):  
Therese I. Poirier
Keyword(s):  
Renal Failure ◽  
Prostaglandin Synthesis ◽  
Predisposing Factors ◽  
Analgesic Nephropathy ◽  
Probable Case ◽  
Renal Deterioration ◽  
Inhibit Prostaglandin Synthesis ◽  
Risk Patients ◽  
Inflammatory Drugs

A report of a probable case of acute, reversible renal failure and hyperkalemia, after an increase in dose of ibuprofen, is presented. Other cases of renal dysfunction associated with various nonsteroidal anti-inflammatory drugs (NSAIDs) are reviewed. The ability of NSAIDs to inhibit prostaglandin synthesis may explain the various renal consequences. Possible predisposing factors to renal deterioration include the amount of drug consumed, presence of compromised renal blood flow, underlying renal insufficiency, nephrotoxic drug combinations, and high urinary prostaglandin excretion. Generally, the renal failure with NSAIDs is acute and reversible, though analgesic nephropathy with papillary necrosis and chronic renal failure are reported. Electrolytes, blood urea nitrogen, and serum creatinine levels need to be monitored in high-risk patients with predisposing factors and for chronic, long-term use of drugs that inhibit prostaglandin synthesis.

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