scholarly journals Generalized SEIR Epidemic Model for COVID-19 in a Multipatch Environment

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Lan Meng ◽  
Wei Zhu
Keyword(s):  
Dynamic Behavior ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Migration Rate ◽  
Reproduction Number ◽  
Actual Data ◽  
Population Migration ◽  
Disease Free ◽  
The Basic Reproduction Number

In this paper, an n -patch SEIR epidemic model for the coronavirus disease 2019 (COVID-19) is presented. It is shown that there is unique disease-free equilibrium for this model. Then, the dynamic behavior is studied by the basic reproduction number. The transmission of COVID-19 is fitted based on actual data. The influence of quarantined rate and population migration rate on the spread of COVID-19 is also discussed by simulation.

scholarly journals Analysis of COVID-19 based on SEIR epidemic models in a multi-patch environment

2021 ◽  
Author(s):  
Lan Meng ◽  
Wei Zhu
Keyword(s):  
Numerical Simulations ◽  
Dynamic Behavior ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Migration Rate ◽  
Reproduction Number ◽  
Population Migration ◽  
Theoretical Results ◽  
Disease Free ◽  
The Basic Reproduction Number

Abstract In this paper, an n-patch SEIR epidemic model for the coronavirus disease 2019 (COVID-19) is presented. It is shown that there is unique disease-free equilibrium for this model. Then, the dynamic behavior is studied by the basic reproduction number. Some numerical simulations with three patches are given to validate the effectiveness of the theoretical results. The influence of quarantined rate and population migration rate on the basic reproduction number is also discussed by simulation.

scholarly journals On an SEIR Epidemic Model with Vaccination of Newborns and Periodic Impulsive Vaccination with Eventual On-Line Adapted Vaccination Strategies to the Varying Levels of the Susceptible Subpopulation

2020 ◽  
Vol 10 (22) ◽  
pp. 8296 ◽  
Author(s):  
Malen Etxeberria-Etxaniz ◽  
Santiago Alonso-Quesada ◽  
Manuel De la Sen
Keyword(s):  
Equilibrium Point ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Disease Transmission ◽  
Reproduction Number ◽  
Equilibrium Points ◽  
Endemic Equilibrium ◽  
Impulsive Vaccination ◽  
Disease Free ◽  
The Basic Reproduction Number

This paper investigates a susceptible-exposed-infectious-recovered (SEIR) epidemic model with demography under two vaccination effort strategies. Firstly, the model is investigated under vaccination of newborns, which is fact in a direct action on the recruitment level of the model. Secondly, it is investigated under a periodic impulsive vaccination on the susceptible in the sense that the vaccination impulses are concentrated in practice in very short time intervals around a set of impulsive time instants subject to constant inter-vaccination periods. Both strategies can be adapted, if desired, to the time-varying levels of susceptible in the sense that the control efforts be increased as those susceptible levels increase. The model is discussed in terms of suitable properties like the positivity of the solutions, the existence and allocation of equilibrium points, and stability concerns related to the values of the basic reproduction number. It is proven that the basic reproduction number lies below unity, so that the disease-free equilibrium point is asymptotically stable for larger values of the disease transmission rates under vaccination controls compared to the case of absence of vaccination. It is also proven that the endemic equilibrium point is not reachable if the disease-free one is stable and that the disease-free equilibrium point is unstable if the reproduction number exceeds unity while the endemic equilibrium point is stable. Several numerical results are investigated for both vaccination rules with the option of adapting through ime the corresponding efforts to the levels of susceptibility. Such simulation examples are performed under parameterizations related to the current SARS-COVID 19 pandemic.

scholarly journals Global Dynamics of an SIQR Model with Vaccination and Elimination Hybrid Strategies

Mathematics ◽  
2018 ◽  
Vol 6 (12) ◽  
pp. 328 ◽  
Author(s):  
Yanli Ma ◽  
Jia-Bao Liu ◽  
Haixia Li
Keyword(s):  
Lyapunov Function ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Endemic Equilibrium ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Disease Free ◽  
The Basic Reproduction Number

In this paper, an SIQR (Susceptible, Infected, Quarantined, Recovered) epidemic model with vaccination, elimination, and quarantine hybrid strategies is proposed, and the dynamics of this model are analyzed by both theoretical and numerical means. Firstly, the basic reproduction number R 0 , which determines whether the disease is extinct or not, is derived. Secondly, by LaSalles invariance principle, it is proved that the disease-free equilibrium is globally asymptotically stable when R 0 < 1 , and the disease dies out. By Routh-Hurwitz criterion theory, we also prove that the disease-free equilibrium is unstable and the unique endemic equilibrium is locally asymptotically stable when R 0 > 1 . Thirdly, by constructing a suitable Lyapunov function, we obtain that the unique endemic equilibrium is globally asymptotically stable and the disease persists at this endemic equilibrium if it initially exists when R 0 > 1 . Finally, some numerical simulations are presented to illustrate the analysis results.

THRESHOLD DYNAMICS IN A PERIODIC SVEIR EPIDEMIC MODEL

2011 ◽  
Vol 04 (04) ◽  
pp. 493-509 ◽  
Author(s):  
JINLIANG WANG ◽  
SHENGQIANG LIU ◽  
YASUHIRO TAKEUCHI
Keyword(s):  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Dynamical Behavior ◽  
Threshold Dynamics ◽  
Globally Asymptotically Stable ◽  
Infectious Risk ◽  
Persistence Theory ◽  
Disease Free ◽  
The Basic Reproduction Number

In this paper, we investigate the dynamical behavior of a class of periodic SVEIR epidemic model. Since the nonautonomous phenomenon often occurs as cyclic pattern, our model is then a periodic time-dependent system. It follows from persistence theory that the basic reproduction number is the threshold parameter above which the disease is uniformly persistent and below which disease-free periodic solution is globally asymptotically stable. The threshold dynamics extends the classic results for the corresponding autonomous model. Furthermore, we show that eradication policy on the basis of the basic reproduction number of the autonomous system may overestimate the infectious risk when the disease follows periodic behavior. The according simulation results are also given.

Global stability and vaccination of an SEIVR epidemic model with saturated incidence rate

2016 ◽  
Vol 09 (05) ◽  
pp. 1650068 ◽  
Author(s):  
Muhammad Altaf Khan ◽  
Yasir Khan ◽  
Sehra Khan ◽  
Saeed Islam
Keyword(s):  
Global Stability ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Endemic Equilibrium ◽  
Asymptotically Stable ◽  
Saturated Incidence Rate ◽  
Saturated Incidence ◽  
Disease Free ◽  
The Basic Reproduction Number

This study considers SEIVR epidemic model with generalized nonlinear saturated incidence rate in the host population horizontally to estimate local and global equilibriums. By using the Routh–Hurwitz criteria, it is shown that if the basic reproduction number [Formula: see text], the disease-free equilibrium is locally asymptotically stable. When the basic reproduction number exceeds the unity, then the endemic equilibrium exists and is stable locally asymptotically. The system is globally asymptotically stable about the disease-free equilibrium if [Formula: see text]. The geometric approach is used to present the global stability of the endemic equilibrium. For [Formula: see text], the endemic equilibrium is stable globally asymptotically. Finally, the numerical results are presented to justify the mathematical results.

scholarly journals Kestabilan Model Epidemi Seir dengan Matriks Hurwitz

2016 ◽  
Vol 11 (2) ◽  
pp. 74
Author(s):  
Roni Tri Putra ◽  
Sukatik - ◽  
Sri Nita
Keyword(s):  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Local Stability ◽  
Reproduction Number ◽  
Equilibrium Points ◽  
Asymptotically Stable ◽  
Stability Of Equilibrium ◽  
Disease Free ◽  
The Basic Reproduction Number

In this paper, it will be studied local stability of equilibrium points of  a SEIR epidemic model with infectious force in latent, infected and immune period. From the model it will be found investigated the existence and its stability of points its equilibrium by Hurwitz matrices. The local stability of equilibrium points is depending on the value of the basic reproduction number  If   the disease free equilibrium is local asymptotically stable.

scholarly journals Analisis dinamik model SVEIR pada penyebaran penyakit campak

2020 ◽  
Vol 1 (2) ◽  
pp. 57-64
Author(s):  
Sitty Oriza Sativa Putri Ahaya ◽  
Emli Rahmi ◽  
Nurwan Nurwan
Keyword(s):  
Equilibrium Point ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Total Population ◽  
Reproduction Number ◽  
Equilibrium Points ◽  
Transmission Model ◽  
Asymptotically Stable ◽  
Disease Free ◽  
The Basic Reproduction Number

In this article, we analyze the dynamics of measles transmission model with vaccination via an SVEIR epidemic model. The total population is divided into five compartments, namely the Susceptible, Vaccinated, Exposed, Infected, and Recovered populations. Firstly, we determine the equilibrium points and their local asymptotically stability properties presented by the basic reproduction number R0. It is found that the disease free equilibrium point is locally asymptotically stable if satisfies R01 and the endemic equilibrium point is locally asymptotically stable when R01. We also show the existence of forward bifurcation driven by some parameters that influence the basic reproduction number R0 i.e., the infection rate α or proportion of vaccinated individuals θ. Lastly, some numerical simulations are performed to support our analytical results.

scholarly journals Partial Differential Equations of an Epidemic Model with Spatial Diffusion

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
El Mehdi Lotfi ◽  
Mehdi Maziane ◽  
Khalid Hattaf ◽  
Noura Yousfi
Keyword(s):  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Reaction Diffusion ◽  
Endemic Equilibrium ◽  
Asymptotically Stable ◽  
Sir Epidemic Model ◽  
Globally Asymptotically Stable ◽  
Disease Free ◽  
The Basic Reproduction Number

The aim of this paper is to study the dynamics of a reaction-diffusion SIR epidemic model with specific nonlinear incidence rate. The global existence, positivity, and boundedness of solutions for a reaction-diffusion system with homogeneous Neumann boundary conditions are proved. The local stability of the disease-free equilibrium and endemic equilibrium is obtained via characteristic equations. By means of Lyapunov functional, the global stability of both equilibria is investigated. More precisely, our results show that the disease-free equilibrium is globally asymptotically stable if the basic reproduction number is less than or equal to unity, which leads to the eradication of disease from population. When the basic reproduction number is greater than unity, then disease-free equilibrium becomes unstable and the endemic equilibrium is globally asymptotically stable; in this case the disease persists in the population. Numerical simulations are presented to illustrate our theoretical results.

scholarly journals Global Stability of an Epidemic Model with Incomplete Treatment and Vaccination

2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
Hai-Feng Huo ◽  
Li-Xiang Feng
Keyword(s):  
Global Stability ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Incomplete Treatment ◽  
Disease Free ◽  
The Basic Reproduction Number

An epidemic model with incomplete treatment and vaccination for the newborns and susceptibles is constructed. We establish that the global dynamics are completely determined by the basic reproduction numberR0. IfR0≤1, then the disease-free equilibrium is globally asymptotically stable. IfR0>1, the endemic equilibrium is globally asymptotically stable. Some numerical simulations are also given to explain our conclusions.

Analysis of a delayed epidemic model with non-monotonic incidence rate and vertical transmission

2014 ◽  
Vol 07 (04) ◽  
pp. 1450041
Author(s):  
Jinhu Xu ◽  
Wenxiong Xu ◽  
Yicang Zhou
Keyword(s):  
Vertical Transmission ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Sufficient Conditions ◽  
Endemic Equilibrium ◽  
Globally Asymptotically Stable ◽  
Comparison Arguments ◽  
Disease Free ◽  
The Basic Reproduction Number

A delayed SEIR epidemic model with vertical transmission and non-monotonic incidence is formulated. The equilibria and the threshold of the model have been determined on the bases of the basic reproduction number. The local stability of disease-free equilibrium and endemic equilibrium is established by analyzing the corresponding characteristic equations. By comparison arguments, it is proved that, if R0 < 1, the disease-free equilibrium is globally asymptotically stable. Whereas, the disease-free equilibrium is unstable if R0 > 1. Moreover, we show that the disease is permanent if the basic reproduction number is greater than one. Furthermore, the sufficient conditions are obtained for the global asymptotic stability of the endemic equilibrium when R0 > 1.

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