Targeting Estrogen Receptor Sites in Human Breast Cancer Cell Line T47D With Copper Conjugates of Nonsteriodal Anti-inflammatory Drug Derivatives: Antiproliferative Activity
of Ketoprofen Derivative and its Copper Complex
Keyword(s):
A square planar copper complex of derivatized NSAID drug (Ketoprofen thiosemicarbazone [3-benzoyl-α -methyl benzene acetic acid thiosemicarbazone]), is characterized by elemental analysis, spectroscopy, electrochemistry and magnetic susceptibility studies which exhibits dose-dependent and enhanced antiproliferative effects on human breast cancer cell line T47D rich in progesterone receptors.
2003 ◽
Vol 278
(44)
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pp. 43363-43372
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2014 ◽
Vol 30
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pp. 140-149
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1992 ◽
Vol 292
(1)
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pp. 136-140
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2003 ◽
Vol 32
(8)
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pp. 1595-1603
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