Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia

Karen Sachs; Aaron L. Sarver; Klara E. Noble-Orcutt; Rebecca S. LaRue; Marie Lue Antony; Daniel Chang; Yoonkyu Lee; Connor M. Navis; Alexandria L. Hillesheim; Ian R. Nykaza; Ngoc A. Ha; Conner J. Hansen; Fatma K. Karadag; Rachel J. Bergerson; Michael R. Verneris; Matthew M. Meredith; Matthew L. Schomaker; Michael A. Linden; Chad L. Myers; David A. Largaespada; Zohar Sachs

doi:10.1158/0008-5472.can-18-2932

Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia

Cancer Research ◽

10.1158/0008-5472.can-18-2932 ◽

2019 ◽

Vol 80 (3) ◽

pp. 458-470 ◽

Cited By ~ 1

Author(s):

Karen Sachs ◽

Aaron L. Sarver ◽

Klara E. Noble-Orcutt ◽

Rebecca S. LaRue ◽

Marie Lue Antony ◽

...

Keyword(s):

Gene Expression ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Cell Compartment ◽

Leukemia Stem Cell ◽

Stem Cell Compartment ◽

Gene Expression Analyses ◽

Cell Gene Expression ◽

Cell Gene ◽

Acute Myeloid

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Leukemia stem cell gene expression signatures contribute to acute myeloid leukemia risk stratification

Haematologica ◽

10.3324/haematol.2019.241117 ◽

2020 ◽

Vol 105 (3) ◽

pp. 533-536

Author(s):

Katherine L. B. Knorr ◽

Aaron D. Goldberg

Keyword(s):

Gene Expression ◽

Acute Myeloid Leukemia ◽

Stem Cell ◽

Risk Stratification ◽

Myeloid Leukemia ◽

Leukemia Stem Cell ◽

Cell Gene Expression ◽

Cell Gene ◽

Stem Cell Gene ◽

Acute Myeloid

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Stratification of pediatric acute myeloid leukemia through cancer cell gene-expression profiling

Expert Review of Anticancer Therapy ◽

10.1586/era.11.8 ◽

2011 ◽

Vol 11 (3) ◽

pp. 355-357 ◽

Cited By ~ 1

Author(s):

Bjørn Tore Gjertsen

Keyword(s):

Gene Expression ◽

Acute Myeloid Leukemia ◽

Gene Expression Profiling ◽

Cancer Cell ◽

Expression Profiling ◽

Myeloid Leukemia ◽

Pediatric Acute Myeloid Leukemia ◽

Cell Gene Expression ◽

Cell Gene ◽

Acute Myeloid

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Identification and Characterization of Acute Myeloid Leukemia-Stem Cells by Single-Cell Gene-Expression Profile

Annals of Oncology ◽

10.1093/annonc/mds552 ◽

2012 ◽

Vol 23 ◽

pp. xi24

Author(s):

H. Tanaka ◽

H. Akimaru ◽

Y. Kanakura ◽

I. Matsumura

Keyword(s):

Gene Expression ◽

Stem Cells ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Stem Cells ◽

Cell Gene Expression ◽

Cell Gene ◽

Identification And Characterization ◽

Acute Myeloid

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Association of a Leukemic Stem Cell Gene Expression Signature With Clinical Outcomes in Acute Myeloid Leukemia

JAMA ◽

10.1001/jama.2010.1862 ◽

2010 ◽

Vol 304 (24) ◽

pp. 2706 ◽

Cited By ~ 219

Author(s):

Andrew J. Gentles

Keyword(s):

Gene Expression ◽

Acute Myeloid Leukemia ◽

Stem Cell ◽

Myeloid Leukemia ◽

Gene Expression Signature ◽

Leukemic Stem Cell ◽

Cell Gene Expression ◽

Cell Gene ◽

Stem Cell Gene ◽

Acute Myeloid

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Complexity of the human acute myeloid leukemia stem cell compartment: Implications for therapy

Biology of Blood and Marrow Transplantation ◽

10.1016/j.bbmt.2004.11.007 ◽

2005 ◽

Vol 11 (2) ◽

pp. 9-11 ◽

Cited By ~ 6

Author(s):

John E. Dick

Keyword(s):

Acute Myeloid Leukemia ◽

Stem Cell ◽

Myeloid Leukemia ◽

Cell Compartment ◽

Leukemia Stem Cell ◽

Stem Cell Compartment ◽

Human Acute Myeloid Leukemia ◽

Acute Myeloid

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Leukemic Stem Cell Gene Expression Signature and Clinical Outcomes in Acute Myeloid Leukemia—Reply

JAMA ◽

10.1001/jama.2011.300 ◽

2011 ◽

Vol 305 (11) ◽

pp. 1094

Author(s):

Andrew J. Gentles

Keyword(s):

Gene Expression ◽

Acute Myeloid Leukemia ◽

Stem Cell ◽

Myeloid Leukemia ◽

Gene Expression Signature ◽

Leukemic Stem Cell ◽

Cell Gene Expression ◽

Cell Gene ◽

Stem Cell Gene ◽

Acute Myeloid

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Altered Hematopoietic Cell Gene Expression Precedes Development of Therapy-Related Myelodysplasia/Acute Myeloid Leukemia and Identifies Patients at Risk

Cancer Cell ◽

10.1016/j.ccr.2011.09.011 ◽

2011 ◽

Vol 20 (5) ◽

pp. 591-605 ◽

Cited By ~ 61

Author(s):

Liang Li ◽

Min Li ◽

Canlan Sun ◽

Liton Francisco ◽

Sujata Chakraborty ◽

...

Keyword(s):

Gene Expression ◽

At Risk ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Hematopoietic Cell ◽

Patients At Risk ◽

Cell Gene Expression ◽

Cell Gene ◽

Acute Myeloid

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Leukemic Stem Cell Gene Expression Signature and Clinical Outcomes in Acute Myeloid Leukemia

JAMA ◽

10.1001/jama.2011.299 ◽

2011 ◽

Vol 305 (11) ◽

pp. 1094 ◽

Cited By ~ 2

Author(s):

Shigeo Masuda

Keyword(s):

Gene Expression ◽

Acute Myeloid Leukemia ◽

Stem Cell ◽

Myeloid Leukemia ◽

Gene Expression Signature ◽

Leukemic Stem Cell ◽

Cell Gene Expression ◽

Cell Gene ◽

Stem Cell Gene ◽

Acute Myeloid

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Clonal Chromosomal Abnormalities in the Stem Cell Compartment of a Patient with Acute Myeloid Leukemia in Hematological Complete Remission

Haematology and Blood Transfusion / Hämatologie und Bluttransfusion - Acute Leukemias VII ◽

10.1007/978-3-642-71960-8_140 ◽

1998 ◽

pp. 1007-1011

Author(s):

M. Feuring-Buske ◽

D. Haase ◽

D. Grove ◽

C. Buske ◽

W. Hiddemann ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Stem Cell ◽

Complete Remission ◽

Myeloid Leukemia ◽

Chromosomal Abnormalities ◽

Cell Compartment ◽

Stem Cell Compartment ◽

Acute Myeloid

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Clonal chromosomal abnormalities in the stem cell compartment of patients with acute myeloid leukemia in morphological complete remission

Leukemia ◽

10.1038/sj.leu.2401300 ◽

1999 ◽

Vol 13 (3) ◽

pp. 386-392 ◽

Cited By ~ 13

Author(s):

M Feuring-Buske ◽

D Haase ◽

C Buske ◽

W Hiddemann ◽

B Wörmann

Keyword(s):

Acute Myeloid Leukemia ◽

Stem Cell ◽

Complete Remission ◽

Myeloid Leukemia ◽

Chromosomal Abnormalities ◽

Cell Compartment ◽

Stem Cell Compartment ◽

Acute Myeloid

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