scholarly journals SKLB-23bb, A HDAC6-Selective Inhibitor, Exhibits Superior and Broad-Spectrum Antitumor Activity via Additionally Targeting Microtubules

2018 ◽  
Vol 17 (4) ◽  
pp. 763-775 ◽  
Author(s):  
Fang Wang ◽  
Li Zheng ◽  
Yuyao Yi ◽  
Zhuang Yang ◽  
Qiang Qiu ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Broad Spectrum ◽  
Selective Inhibitor

scholarly journals TAK-960, a Novel, Orally Available, Selective Inhibitor of Polo-Like Kinase 1, Shows Broad-spectrum Preclinical Antitumor Activity in Multiple Dosing Regimens

2011 ◽  
Vol 11 (3) ◽  
pp. 700-709 ◽  
Author(s):  
Yuichi Hikichi ◽  
Kohei Honda ◽  
Kouki Hikami ◽  
Hitoshi Miyashita ◽  
Isao Kaieda ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Broad Spectrum ◽  
Selective Inhibitor ◽  
Multiple Dosing ◽  
Dosing Regimens

scholarly journals Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2

2010 ◽  
Vol 333 (1) ◽  
pp. 129-139 ◽  
Author(s):  
Kevin J. French ◽  
Yan Zhuang ◽  
Lynn W. Maines ◽  
Peng Gao ◽  
Wenxue Wang ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Sphingosine Kinase ◽  
Selective Inhibitor ◽  
Sphingosine Kinase 2

Abstract B235: Characterization of LY2228820 dimesylate, a potent and selective inhibitor of p38 MAPK with antitumor activity.

2011 ◽  
Author(s):  
Robert M. Campbell ◽  
Bryan D. Anderson ◽  
Edward M. Chan ◽  
Alfonso De Dios ◽  
Raymond Gilmour ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
P38 Mapk ◽  
Selective Inhibitor

Abstract LB-159: A novel, potent and selective inhibitor of Wee1 with robust antitumor activity in various cancer xenograph models

2016 ◽  
Author(s):  
Gerald Gavory ◽  
Colin O’Dowd ◽  
Frank Burkamp ◽  
Shane Rountree ◽  
Ewelina Rozycka ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Selective Inhibitor

Characterization of a selective inhibitor for matrix metalloproteinase-8 (MMP-8)

MedChemComm ◽  
2014 ◽  
Vol 5 (9) ◽  
pp. 1381-1383 ◽  
Author(s):  
Derong Ding ◽  
Katerina Lichtenwalter ◽  
Hualiang Pi ◽  
Shahriar Mobashery ◽  
Mayland Chang
Keyword(s):  
Matrix Metalloproteinase ◽  
Broad Spectrum ◽  
Selective Inhibitor ◽  
Mmp Inhibitor

MMP-8 has been implicated in various diseases using a reported selective MMP-8 inhibitor that is actually a broad-spectrum MMP inhibitor.

A novel CDC7-selective inhibitor TAK-931 with potent antitumor activity

2016 ◽  
Vol 69 ◽  
pp. S34 ◽  
Author(s):  
K. Iwai ◽  
N. Tadahiro ◽  
O. Kurasawa ◽  
N. Uchiyama ◽  
A. Ohashi
Keyword(s):  
Antitumor Activity ◽  
Selective Inhibitor

Fluorocyclopentenyl-cytosine with Broad Spectrum and Potent Antitumor Activity

2012 ◽  
Vol 55 (9) ◽  
pp. 4521-4525 ◽  
Author(s):  
Won Jun Choi ◽  
Hwa-Jin Chung ◽  
Girish Chandra ◽  
Varughese Alexander ◽  
Long Xuan Zhao ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Broad Spectrum
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