Abstract C198: CX‐4945, a novel small molecule inhibitor of CK2 protein kinase, reduces hyperactivated Akt signaling and synergizes with Akt inhibitors in breast cancer cells

2009 ◽  
Author(s):  
Denis Drygin ◽  
Josh Bliesath ◽  
Caroline Ho ◽  
Adam Siddiqui‐Jain ◽  
Sean O'Brien ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Protein Kinase ◽  
Cancer Cells ◽  
Small Molecule ◽  
Breast Cancer Cells ◽  
Small Molecule Inhibitor ◽  
Akt Signaling ◽  
Molecule Inhibitor

PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells

2017 ◽  
Vol 77 (22) ◽  
pp. 6253-6266 ◽  
Author(s):  
Jiangmei Li ◽  
Zhen Gao ◽  
Dan Zhao ◽  
Lunfeng Zhang ◽  
Xinhua Qiao ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Small Molecule ◽  
Breast Cancer Cells ◽  
Small Molecule Inhibitor ◽  
Molecule Inhibitor

Abstract 1634: A novel small molecule inhibitor of IRE1alpha reverses endocrine resistance in breast cancer cells

2014 ◽  
Author(s):  
Ayesha N. Shajahan-Haq ◽  
Jacqueline Smith ◽  
Siva Dakshanamurthy ◽  
Difei Wang ◽  
Ahreej E. Eltayeb ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Small Molecule ◽  
Breast Cancer Cells ◽  
Endocrine Resistance ◽  
Small Molecule Inhibitor ◽  
Molecule Inhibitor

Breast Cancer Cells Can Evade Apoptosis-Mediated Selective Killing by a Novel Small Molecule Inhibitor of Bcl-2

2004 ◽  
Vol 64 (21) ◽  
pp. 7947-7953 ◽  
Author(s):  
Pedro Jose Real ◽  
Yeyu Cao ◽  
Renxiao Wang ◽  
Zaneta Nikolovska-Coleska ◽  
Jaime Sanz-Ortiz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Small Molecule ◽  
Breast Cancer Cells ◽  
Small Molecule Inhibitor ◽  
Molecule Inhibitor
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