Abstract 2498: BNC105 is a tubulin polymerization inhibitor that exhibits vascular disruptive activity in renal cancer and causes upregulation in HIF1alpha, HIF2alpha and mTOR

2010 ◽  
Author(s):  
Annabell F. Leske ◽  
Donna M. Beaumont ◽  
Tina C. Lavranos ◽  
Jelena Gasic ◽  
Carolyn J. Coles ◽  
...  
Keyword(s):  
Renal Cancer ◽  
Tubulin Polymerization ◽  
Polymerization Inhibitor ◽  
Tubulin Polymerization Inhibitor

Pharmacokinetics of synthadotin (ILX651), a novel tubulin polymerization inhibitor, in patients with solid tumors

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 2082-2082
Author(s):  
P. Bonate ◽  
S. Ebbinghaus ◽  
J. P. Eder ◽  
A. Mita ◽  
E. Rubin ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Tubulin Polymerization ◽  
Polymerization Inhibitor ◽  
Tubulin Polymerization Inhibitor

Pharmacokinetics of synthadotin (ILX651), a novel tubulin polymerization inhibitor, in patients with solid tumors

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 2082-2082
Author(s):  
P. Bonate ◽  
S. Ebbinghaus ◽  
J. P. Eder ◽  
A. Mita ◽  
E. Rubin ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Tubulin Polymerization ◽  
Polymerization Inhibitor ◽  
Tubulin Polymerization Inhibitor

Abstract 2794: Cytotoxic and vascular disrupting activity of EHT 6706, a novel tubulin polymerization inhibitor

2012 ◽  
Author(s):  
Anne-Sophie Casagrande ◽  
Florence Bachelot ◽  
Catherine De Oliveira ◽  
Séverine Coutadeur ◽  
Rachel Carton ◽  
...  
Keyword(s):  
Tubulin Polymerization ◽  
Polymerization Inhibitor ◽  
Tubulin Polymerization Inhibitor ◽  
Vascular Disrupting
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