Abstract 1743: Phase 1 clinical trial of the base-excision repair inhibitor Methoxyamine-HCl (TRC102; MX) in combination with Temozolomide (TMZ) in patients with solid tumors

2012 ◽  
Author(s):  
Panos S. Savvides ◽  
Yan Xu ◽  
Lili Liu ◽  
Lisa Rogers ◽  
Joseph Bokar ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Solid Tumors ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Phase 1 ◽  
Phase 1 Clinical Trial ◽  
Base Excision

scholarly journals A phase 1 study of TRC102, an inhibitor of base excision repair, and pemetrexed in patients with advanced solid tumors

2012 ◽  
Vol 31 (3) ◽  
pp. 714-723 ◽  
Author(s):  
Michael S. Gordon ◽  
Lee S. Rosen ◽  
David Mendelson ◽  
Ramesh K. Ramanathan ◽  
Jonathan Goldman ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Phase 1 ◽  
Advanced Solid Tumors ◽  
Phase 1 Study ◽  
Base Excision

scholarly journals Final Report on Phase 1 Clinical Trial of Oral Pparгagonist Efatutazone (CS-7017) in Japanese Patients with Metastatic Solid Tumors

2012 ◽  
Vol 23 ◽  
pp. xi110-xi111
Author(s):  
Y. Onozawa ◽  
H. Murakami ◽  
A. Ono ◽  
T. Tushima ◽  
T. Takahashi ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Solid Tumors ◽  
Phase 1 ◽  
Japanese Patients ◽  
Final Report ◽  
Phase 1 Clinical Trial

scholarly journals Phase I clinical trial of the base excision repair inhibitor methoxyamine in combination with fludarabine for patients with advanced hematologic malignancies

Oncotarget ◽  
2017 ◽  
Vol 8 (45) ◽  
pp. 79864-79875 ◽  
Author(s):  
Paolo F. Caimi ◽  
Brenda W. Cooper ◽  
Basem M. William ◽  
Afshin Dowlati ◽  
Paul M. Barr ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Phase I ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Hematologic Malignancies ◽  
Phase I Clinical Trial ◽  
Base Excision

scholarly journals A phase 1 clinical trial of sequential pralatrexate followed by a 48-hour infusion of 5-fluorouracil given every other week in adult patients with solid tumors

Cancer ◽  
2015 ◽  
Vol 121 (21) ◽  
pp. 3862-3868 ◽  
Author(s):  
Jean L. Grem ◽  
Mary E. Kos ◽  
Ruby E. Evande ◽  
Jane L. Meza ◽  
James K. Schwarz
Keyword(s):  
Clinical Trial ◽  
Solid Tumors ◽  
Phase 1 ◽  
Adult Patients ◽  
Phase 1 Clinical Trial

Modulation of Base Excision Repair Alters Cellular Sensitivity to UVA1 but not to UVB¶

2002 ◽  
Vol 75 (5) ◽  
pp. 507 ◽  
Author(s):  
Katherine J. Kim ◽  
Indraneel Chakrabarty ◽  
Guang-Zhi Li ◽  
Sabine Grösch ◽  
Bernd Kaina ◽  
...  
Keyword(s):  
Base Excision Repair ◽  
Excision Repair ◽  
Cellular Sensitivity ◽  
Base Excision

Defective Base Excision Repair Associated with NTHL1

2019 ◽  
Vol 68 ◽  
Author(s):  
Richarda de Voer ◽  
Paul W Doetsch ◽  
Roland Kuiper ◽  
Barbara Rivera
Keyword(s):  
Base Excision Repair ◽  
Excision Repair ◽  
Base Excision
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