Abstract 4063: Design and synthesis of indole derivatives as ABCG2 mediated resistance reversal agents

2017 ◽  
Author(s):  
Chao-Yun Cai ◽  
Hong Zhai ◽  
Zi-Ning Lei ◽  
Bao-Li Chen ◽  
Zhao-Yi Du ◽  
...  
Keyword(s):  
Indole Derivatives ◽  
Reversal Agents ◽  
Design And Synthesis ◽  
Resistance Reversal

Design and synthesis of an optimized positional scanning library of peptoids: identification of novel multidrug resistance reversal agents

2005 ◽  
Vol 13 (6) ◽  
pp. 1923-1929 ◽  
Author(s):  
Isabel Masip ◽  
Nuria Cortés ◽  
Maria-José Abad ◽  
Marisa Guardiola ◽  
Enrique Pérez-Payá ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Reversal Agents ◽  
Design And Synthesis ◽  
Positional Scanning ◽  
Resistance Reversal

Synthesis and Biological Evaluation of C-Aromataxane Derivatives as P-Glycoprotein-Mediated Multi Drug Resistance Reversal Agents

Heterocycles ◽  
2015 ◽  
Vol 90 (1) ◽  
pp. 482
Author(s):  
Takayuki Doi ◽  
Naoko Yamaguchi ◽  
Kosuke Ohsawa ◽  
Kazuoki Nakai ◽  
Masahito Yoshida ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Biological Evaluation ◽  
Multi Drug Resistance ◽  
Reversal Agents ◽  
P Glycoprotein ◽  
Resistance Reversal ◽  
Synthesis And Biological Evaluation

Multidrug Resistance Reversal Agents

ChemInform ◽  
2004 ◽  
Vol 35 (6) ◽  
Author(s):  
Jacques Robert ◽  
Christian Jarry
Keyword(s):  
Multidrug Resistance ◽  
Reversal Agents ◽  
Resistance Reversal

scholarly journals Dihydroethanoanthracene Derivatives as In Vitro Malarial Chloroquine Resistance Reversal Agents

2004 ◽  
Vol 48 (7) ◽  
pp. 2753-2756 ◽  
Author(s):  
Julie Millet ◽  
Marylin Torrentino-Madamet ◽  
Sandrine Alibert ◽  
Christophe Rogier ◽  
Christiane Santelli-Rouvier ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Chloroquine Resistance ◽  
Reversal Agents ◽  
Resistance Reversal

ABSTRACT The ability of four 9,10-dihydroethanoanthracene derivatives (BG920, BG932, BG958, and BG996), as well as verapamil and promethazine, to reverse chloroquine resistance was assessed against 24 chloroquine-resistant and 10 chloroquine-susceptible strains of Plasmodium falciparum from different countries. The 9,10-dihydroethanoanthracene derivatives clearly increase chloroquine susceptibility only in chloroquine-resistant isolates.

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