ChemInform Abstract: Design and Synthesis of Tetrahydroisoquinoline Derivatives as Potential Multidrug Resistance Reversal Agents in Cancer.

ChemInform ◽  
2008 ◽  
Vol 39 (45) ◽  
Author(s):  
Yu Li ◽  
Hui-bin Zhang ◽  
Wen-long Huang ◽  
Yun-man Li
Keyword(s):  
Multidrug Resistance ◽  
Reversal Agents ◽  
Design And Synthesis ◽  
Resistance Reversal

Design and synthesis of an optimized positional scanning library of peptoids: identification of novel multidrug resistance reversal agents

2005 ◽  
Vol 13 (6) ◽  
pp. 1923-1929 ◽  
Author(s):  
Isabel Masip ◽  
Nuria Cortés ◽  
Maria-José Abad ◽  
Marisa Guardiola ◽  
Enrique Pérez-Payá ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Reversal Agents ◽  
Design And Synthesis ◽  
Positional Scanning ◽  
Resistance Reversal

Multidrug Resistance Reversal Agents

ChemInform ◽  
2004 ◽  
Vol 35 (6) ◽  
Author(s):  
Jacques Robert ◽  
Christian Jarry
Keyword(s):  
Multidrug Resistance ◽  
Reversal Agents ◽  
Resistance Reversal

Abstract 4063: Design and synthesis of indole derivatives as ABCG2 mediated resistance reversal agents

2017 ◽  
Author(s):  
Chao-Yun Cai ◽  
Hong Zhai ◽  
Zi-Ning Lei ◽  
Bao-Li Chen ◽  
Zhao-Yi Du ◽  
...  
Keyword(s):  
Indole Derivatives ◽  
Reversal Agents ◽  
Design And Synthesis ◽  
Resistance Reversal

Therapeutic Potential of Endophytic Compounds: A Special Reference to Drug Transporter Inhibitors

2019 ◽  
Vol 19 (10) ◽  
pp. 754-783 ◽  
Author(s):  
Khusbu Singh ◽  
Gaurav Raj Dwivedi ◽  
A. Swaroop Sanket ◽  
Sanghamitra Pati
Keyword(s):  
Drug Resistance ◽  
Multidrug Resistance ◽  
Therapeutic Potential ◽  
Drug Transporters ◽  
Chemotherapeutic Agents ◽  
Chemical Diversity ◽  
Drug Transporter ◽  
Reversal Agents ◽  
Resistance Reversal ◽  
Novel Drug

From the discovery to the golden age of antibiotics (miracle), millions of lives have been saved. The era of negligence towards chemotherapeutic agents gave birth to drug resistance. Among all the regulators of drug resistance, drug transporters are considered to be the key regulators for multidrug resistance. These transporters are prevalent from prokaryotes to eukaryotes. Endophytes are one of the unexplored wealths of nature. Endophytes are a model mutualistic partner of plants. They are the reservoir of novel therapeutics. The present review deals with endophytes as novel drug resistance reversal agents by inhibiting the drug transporters across the genera. This review also focuses on drug transporters, and mutualistic chemical diversity, exploring drug transporter modulating potential of endophytes.

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