Abstract CT058: Ripretinib (DCC-2618) pharmacokinetics (PK) in a Phase I study in patients with gastrointestinal stromal tumors (GIST) and other advanced malignancies: A retrospective evaluation of the PK effects of proton pump inhibitors (PPIs)

2019 ◽  
Author(s):  
Filip Janku ◽  
Michael Heinrich ◽  
Ping Chi ◽  
Albiruni Abdul Razak ◽  
Margaret von Mehren ◽  
...  
Keyword(s):  
Phase I ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Gastrointestinal Stromal Tumors ◽  
Phase I Study ◽  
Retrospective Evaluation ◽  
Stromal Tumors ◽  
Advanced Malignancies

scholarly journals A Phase I Study of Single-Agent Nilotinib or in Combination with Imatinib in Patients with Imatinib-Resistant Gastrointestinal Stromal Tumors

2009 ◽  
Vol 15 (18) ◽  
pp. 5910-5916 ◽  
Author(s):  
George D. Demetri ◽  
Paolo G. Casali ◽  
Jean-Yves Blay ◽  
Margaret von Mehren ◽  
Jeffrey A. Morgan ◽  
...  
Keyword(s):  
Phase I ◽  
Gastrointestinal Stromal Tumors ◽  
Phase I Study ◽  
Single Agent ◽  
Stromal Tumors ◽  
Imatinib Resistant

scholarly journals Phase I Study of Rapid Alternation of Sunitinib and Regorafenib for the Treatment of Tyrosine Kinase Inhibitor Refractory Gastrointestinal Stromal Tumors

2019 ◽  
Vol 25 (24) ◽  
pp. 7287-7293 ◽  
Author(s):  
César Serrano ◽  
Alessandro Leal ◽  
Yanan Kuang ◽  
Jeffrey A. Morgan ◽  
Constance M. Barysauskas ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Phase I ◽  
Tyrosine Kinase Inhibitor ◽  
Gastrointestinal Stromal Tumors ◽  
Phase I Study ◽  
Kinase Inhibitor ◽  
Stromal Tumors

scholarly journals A Phase I Study of the HSP90 Inhibitor Retaspimycin Hydrochloride (IPI-504) in Patients with Gastrointestinal Stromal Tumors or Soft-Tissue Sarcomas

2013 ◽  
Vol 19 (21) ◽  
pp. 6020-6029 ◽  
Author(s):  
Andrew J. Wagner ◽  
Rashmi Chugh ◽  
Lee S. Rosen ◽  
Jeffrey A. Morgan ◽  
Suzanne George ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Phase I ◽  
Gastrointestinal Stromal Tumors ◽  
Phase I Study ◽  
Soft Tissue Sarcomas ◽  
Hsp90 Inhibitor ◽  
Stromal Tumors

A phase I study of nilotinib alone and in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors (GIST): Study update

2008 ◽  
Vol 26 (15_suppl) ◽  
pp. 10553-10553 ◽  
Author(s):  
J. Y. Blay ◽  
P. G. Casali ◽  
P. Reichardt ◽  
M. von Mehren ◽  
M. Debiec-Rychter ◽  
...  
Keyword(s):  
Phase I ◽  
Gastrointestinal Stromal Tumors ◽  
Phase I Study ◽  
Stromal Tumors ◽  
Imatinib Resistant

scholarly journals Phase I study of panobinostat and imatinib in patients with treatment-refractory metastatic gastrointestinal stromal tumors

2014 ◽  
Vol 110 (5) ◽  
pp. 1155-1162 ◽  
Author(s):  
S Bauer ◽  
R A Hilger ◽  
T Mühlenberg ◽  
F Grabellus ◽  
J Nagarajah ◽  
...  
Keyword(s):  
Phase I ◽  
Gastrointestinal Stromal Tumors ◽  
Phase I Study ◽  
Stromal Tumors ◽  
Treatment Refractory

Phase I study of liposome-encapsulated c-raf antisense oligodeoxyribonucleotide infusion in combination with radiation therapy in patients with advanced malignancies.

2006 ◽  
Vol 12 (4) ◽  
pp. 1251-1259 ◽  
Author(s):  
Anatoly Dritschilo ◽  
Chao H Huang ◽  
Charles M Rudin ◽  
John Marshall ◽  
Brian Collins ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Phase I ◽  
Phase I Study ◽  
Advanced Malignancies

Phase I study of cisdiamminedichloroplatinum in combination with azidothymidine in the treatment of patients with advanced malignancies

2003 ◽  
Vol 51 (6) ◽  
pp. 459-464 ◽  
Author(s):  
Robert J. Morgan ◽  
Edward M. Newman ◽  
Lawrence Sowers ◽  
Kevin Scanlon ◽  
Jonathan Harrison ◽  
...  
Keyword(s):  
Phase I ◽  
Phase I Study ◽  
Advanced Malignancies
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