Abstract 344: SJP1604, a novel targeted therapeutic agent for AML (acute myeloid leukemia) including standard therapy-resistant AML

2019 ◽  
Author(s):  
Jihyun Um ◽  
Dohyeong Lee ◽  
Jisun Oh ◽  
Yongbin Park ◽  
Sung Hwan Moon ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Standard Therapy ◽  
Myeloid Leukemia ◽  
Therapeutic Agent ◽  
Acute Myeloid ◽  
Targeted Therapeutic

Cardiovascular effects of the addition of nilotinib to standard therapy for acute myeloid leukemia

2017 ◽  
Vol 59 (1) ◽  
pp. 229-232
Author(s):  
Carolyn M. Larsen ◽  
Hector R. Villarraga ◽  
Kebede H. Begna ◽  
Mark R. Litzow ◽  
Aref Al-Kali ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Standard Therapy ◽  
Myeloid Leukemia ◽  
Cardiovascular Effects ◽  
Acute Myeloid

New Trends in the Standard of Care for Initial Therapy of Acute Myeloid Leukemia

Hematology ◽  
2010 ◽  
Vol 2010 (1) ◽  
pp. 56-61 ◽  
Author(s):  
Hugo F. Fernandez
Keyword(s):  
Acute Myeloid Leukemia ◽  
Standard Therapy ◽  
Myeloid Leukemia ◽  
Good Control ◽  
Leukemic Cell ◽  
Initial Therapy ◽  
Gemtuzumab Ozogamicin ◽  
Current Standard ◽  
Molecular Abnormalities ◽  
Acute Myeloid

AbstractIn younger patients with acute myeloid leukemia (AML), initial treatment has provided very good control of the disease. Induction therapy has used combination chemotherapy, with anthracycline and cytarabine as the foundation. Recent trials support dose intensification of anthracycline in induction. Intensive postremission therapy further contributes to improving survival. The addition of targeted therapy with gemtuzumab ozogamicin to standard therapy has not improved on these outcomes. Newer agents targeted to specific molecular abnormalities or survival mechanisms in the leukemic cell are being studied as future additions to the current standard therapy.

Cardiovascular effects of the addition of nilotinib to standard therapy for acute myeloid leukemia.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e18505-e18505
Author(s):  
Carolyn Marie Larsen ◽  
Hector R. Villarraga ◽  
Kebede Begna ◽  
Mark Robert Litzow ◽  
Aref Al-Kali ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Standard Therapy ◽  
Myeloid Leukemia ◽  
Cardiovascular Effects ◽  
Acute Myeloid
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