Abstract
Background
This study aims to identify risk factors associated with in-hospital and 30-days mortality in patients with acute limb ischemia (ALI).
Methods
This study was a single-centered cohort enrolling a total of 160 consecutive patients with a diagnosis of ALI. The ALI diagnosis was based on clinical history, physical examination, and Doppler studies of the extremities. The main outcome of this study is in-hospital and 30-days mortality.
Results
There were a total of 170 patients involving 192 limbs with the diagnosis of ALI. Intra-aortic balloon pump (IABP) insertion (HR 3.4; 95% CI 1.0-11.3, p = 0.042), no vitamin E treatment (HR 5.6; CI 1.7–18.3, 0.004), arrhythmia (HR 12.00; CI 3.8–37.7, p < 0.001), and acute renal failure (HR 6.70; CI 1.88–24.3, p = 0.003) were an independent predictor of intra-hospital mortality. For 30-days mortality, the independent predictors were menopause (HR 3.2; CI 1.16–8.85, p = 0.02); IABP insertion (HR 4.51; CI 1.14–17.92, p = 0.03); arrhythmia (HR 0.11; CI 0.04–0.32, p < 0.001); bleeding requiring transfusion (HR 3.77; CI 0.10-14.28, p = 0.05); and acute renal failure (HR 5.5; CI 1.79–16.95, p = 0.003).
Conclusion
In-hospital mortality in patients with ALI remains high in our center. Several factors contributing to mortality were arrhythmia, renal failure, no vitamin E supplementation, and a history of recent cardiac operation.
Predictors of In-hospital Mortality in Patients with Acute Limb Ischemia – Lesson Learnt from A Tertiary Hospital in Jakarta