Biochemical Studies of Bone from Diabetic Rats and Rats Bearing Transplanted Pancreatic Islets

Pathobiology ◽  
1981 ◽  
Vol 49 (2) ◽  
pp. 61-67 ◽  
Author(s):  
Ruth Silberberg ◽  
David W. Scharp ◽  
Peggy A. Lesker
Diabetes ◽  
1994 ◽  
Vol 43 (11) ◽  
pp. 1345-1352 ◽  
Author(s):  
A. Gardemann ◽  
K. Jungermann ◽  
V. Grosse ◽  
L. Cossel ◽  
F. Wohlrab ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Samira Missaoui ◽  
Khémais Ben Rhouma ◽  
Mohamed-Tahar Yacoubi ◽  
Mohsen Sakly ◽  
Olfa Tebourbi

We examined the effects of vanadium sulfate (VOSO4) treatment at 5 and 10 mg/kg for 30 days on endocrine pancreas activity and histology in nondiabetic and STZ-induced diabetic rats. In diabetic group, blood glucose levels significantly increased while insulinemia level markedly decreased. At the end of treatment, VOSO4at a dose of 10 mg/Kg normalized blood glucose level in diabetic group, restored insulinemia, and significantly improved insulin sensitivity. VOSO4also increased in a dose-dependent manner the number of insulin immunopositive beta cells in pancreatic islets of nondiabetic rats. Furthermore, in the STZ-diabetic group, the decrease in the number of insulin immunopositive beta cells was corrected to reach the control level mainly with the higher dose of vanadium. Therefore, VOSO4treatment normalized plasma glucose and insulin levels and improved insulin sensitivity in STZ-experimental diabetes and induced beta cells proliferation and/or regeneration in normal or diabetic rats.


Pancreas ◽  
1990 ◽  
Vol 5 (5) ◽  
pp. 533-539 ◽  
Author(s):  
César L. A. Gómez Dumm ◽  
Maria C. Semino ◽  
Juan Jose Gagliardino

2007 ◽  
Vol 111 (3) ◽  
pp. 547-552 ◽  
Author(s):  
A.C.R. Leite ◽  
T.G. Araújo ◽  
B.M. Carvalho ◽  
N.H. Silva ◽  
V.L.M. Lima ◽  
...  

2013 ◽  
Vol 430 (2) ◽  
pp. 676-682 ◽  
Author(s):  
Miho Tsuchiya ◽  
Yasuko Manabe ◽  
Kenichiro Yamada ◽  
Yasuro Furuichi ◽  
Masahiro Hosaka ◽  
...  

2003 ◽  
Vol 27 (11) ◽  
pp. 1053-1056 ◽  
Author(s):  
Stephan Schneider ◽  
Marc-Alexander von Mach ◽  
Oliver Kraus ◽  
Peter Kann ◽  
Peter Johannes Feilen;

2009 ◽  
Vol 111 (2) ◽  
pp. 138-144 ◽  
Author(s):  
Yong Pyong Ku ◽  
Ming Jin ◽  
Kyung Hee Kim ◽  
Young Jun Ahn ◽  
Sang Pil Yoon ◽  
...  

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